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Long-Term Vancomycin May Help Prevent Recurrent C. Diff Infections
(MedPage Today) -- WASHINGTON--Long-term vancomycin suppression appeared to help prevent recurrences of Clostridioides difficile infections (CDI) and did not lead to a substantial increase in vancomycin-resistant Enterococcus (VRE), according... -
Tovecimig-Based Doublet Boosts Response and PFS in Advanced Biliary Tract Cancer
(MedPage Today) -- Investigational tovecimig combined with paclitaxel significantly improved the response rate and progression-free survival (PFS) in patients with previously treated advanced or metastatic biliary tract cancer, according to the... -
Novel ADC Achieves Impressive PFS Advantage in HER2-Low Metastatic Breast Cancer
(MedPage Today) -- Patients with recurrent or metastatic HER2-low breast cancer had dramatic improvement in progression-free survival (PFS) when treated with a novel antibody-drug conjugate (ADC) targeting HER2, a large randomized trial showed... -
Patient Death Reported in Multiple Sclerosis CAR-T Study
(MedPage Today) -- The investigational CD19-directed chimeric antigen receptor (CAR) T-cell therapy zolacabtagene autoleucel (zola-cel) showed the potential to treat people with highly active relapsing multiple sclerosis (MS) and progressive MS... -
Atacicpet, Sibeprenlimab Halt Decline in Kidney Function in IgA Nephropathy
(MedPage Today) -- DENVER--Two IgA nephropathy drugs--atacicept (Trutakna) and sibeprenlimab injection (Voyxact)--showed they were able to slow kidney function decline in final phase III trial efficacy analyses.
Atacicept and sibeprenlimab... -
RSV Hospitalization May Be Taking a Surprising Mortality Toll, CDC Finds
(MedPage Today) -- WASHINGTON--Nearly one in 10 adults hospitalized with respiratory syncytial virus (RSV) infection died in the hospital or within 30 days of discharge, according to a CDC analysis of eight RSV seasons.
Among 18,301 adults... -
Clinician AI Use; Predicting Bad Infant Outcomes in Labor; Donor Heart Distribution
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of Texas Tech Health El Paso, look at the top medical... -
An Accurate Census Protects Our Health
(MedPage Today) -- As a physician, I take care of the individual patient in front of me. As a public health leader, communities are my patients. I ask: Who needs care but is not getting it? Where should we focus resources to prevent vaccine-preventable... -
Health Insurance Costs Keep Climbing for American Workers, New Survey Finds
(MedPage Today) -- People who rely on employer-sponsored health insurance paid more for their coverage this year, with employees at small businesses and their employers especially squeezed by the surging costs, according to a new survey by healthcare... -
Endovascular Therapy Eyed for Milder Strokes, Later Time Window
(MedPage Today) -- Endovascular therapy (EVT) made promising forays into milder and later-presenting large vessel occlusion (LVO) strokes in a pair of multicenter, open-label trials from China.
In the MILD-MT trial of people with mild acute ischemic... -
Chinese Drug Shows Benefit in HER2-Low Breast Cancer
(MedPage Today) -- An investigational antibody-drug conjugate (ADC) significantly reduced the risk of disease progression or death in patients with HER2-low metastatic breast cancer, a Chinese phase III trial showed.
The drug, trastuzumab rezetecan... -
Type of Menopause Hormone Therapy Tied to Small Autoimmune Disease Risk
(MedPage Today) -- Estrogen-only menopausal hormone therapy was associated with a slightly higher incidence of autoimmune disease compared with estrogen-progestogen therapy, a retrospective cohort study suggested.
Among over 100,000 women taking... -
Supplement Shows Promise for Improving Cancer-Related Cognitive Impairment
(MedPage Today) -- Cancer-related cognitive impairment (CRCI) in breast cancer survivors improved significantly after treatment with the glutamate regulator oxaloacetate, a preliminary single-arm clinical study showed.
All 16 evaluable patients... -
Infants' Maternal Measles Protection May Not Last Until First MMR Dose
(MedPage Today) -- WASHINGTON--At 6 months of age, most U.S. infants no longer had detectable levels of maternal neutralizing antibodies for measles, potentially leaving them at risk of an infection months before their first dose of the measles... -
What Did Leaked Data on an mRNA Vaccine Show?
(MedPage Today) -- You passed medical training, now see if you can pass our weekly quiz -
No Daytime Grogginess Observed With Menopause Hot Flash Drug
(MedPage Today) -- Taking the nonhormonal dual neurokinin (NK) receptor antagonist elinzanetant (Lynkuet) at bedtime did not result in residual daytime sleepiness and actually improved sleepiness scores in postmenopausal women, according to a pooled... -
Blood Cancer Drug Denials; Body Fat and Pancreas Cancer; Studies With Fake Citations
(MedPage Today) -- Up to 84% of prescriptions for specialty oral cancer drugs for blood cancers were initially denied, according to a nationwide study of claims submitted to Medicare and private insurance companies. (Journal of Clinical Oncology... -
I'm a Forensic Psychiatrist. Here's My Take on the Elizabeth Holmes Documentary.
(MedPage Today) -- Nathan Fielder and Lance Oppenheim's new documentary, "You Can See Everything," tells a story of Elizabeth--now Liz--Holmes in the month leading up to her incarceration at a federal prison camp. Holmes, the disgraced... -
mRNA Melanoma Vaccine Cuts Risk of Recurrence or Death, Leaked Trial Data Show
(MedPage Today) -- Adjuvant treatment with the mRNA-based cancer vaccine intismeran autogene plus pembrolizumab (Keytruda) significantly improved recurrence-free survival (RFS) in patients with resected stage IIB-IV melanoma, the phase III INTerpath... -
Multiple Sclerosis Anti-CD20 Drug Linked to Bowel Disease Risk
(MedPage Today) -- The anti-CD20 agent rituximab was associated with a higher risk of inflammatory bowel disease (IBD) in people with relapsing-remitting multiple sclerosis (MS) compared with other disease-modifying treatments (DMTs), a population... -
Calley Means Resigns as Top RFK Jr. Advisor
(MedPage Today) -- Calley Means, a top advisor to Health Secretary Robert F. Kennedy Jr. and a chief advocate for the Make America Healthy Again (MAHA) movement, resigned from his position with the Trump administration Thursday.
In a statement... -
Quest Diagnostics Reports Cyber Breach Affecting Patient Records
(MedPage Today) -- Medical laboratory operator Quest Diagnostics said it learned of a cyber breach of one of its systems this week, likely compromising some records for patients.
In a Thursday regulatory filing, Quest Diagnostics reported "unauthorized... -
4,687 Dead in Outbreak; Marshall Faulk Has Parkinson's; $2 Billion Healthcare Scheme
(MedPage Today) -- Note that some links may require registration or subscription.
The Congo's fast-spreading Ebola outbreak has amassed 9,704 confirmed cases and 4,687 deaths, according to the CDC.
Meanwhile, the agency will now require all foreign... -
How a transatlantic mega-merger fell apart over a leadership tug of war
via HealthcareSmith & Nephew was in talks to combine with J&J’s orthopaedics unit but refused to agree to former CEO leading combined business -
China’s rapid human trials draw western drugmakers — and safety concerns
via HealthcarePharma groups including AstraZeneca are using a fast-track clinical testing route for cutting-edge medicines -
Donating a Kidney Could Lead to Later Pregnancy Complications
(MedPage Today) -- DENVER--Donating a kidney was associated with a higher risk of gestational hypertensive disorders during subsequent pregnancy, though complications were rare overall, according to a Canadian matched cohort study.
Among women... -
ADHD Drugs May Alleviate Menopausal Brain Fog
(MedPage Today) -- Attention deficit-hyperactivity disorder (ADHD) medications may improve subjective experiences with menopausal brain fog, but more research is needed, a scoping review suggested.
Data from three crossover, randomized controlled... -
Multiple Sclerosis Diagnostic Delays Linked to Specialist, MRI Access
(MedPage Today) -- Disparities in geographic access to neurologists, specialists, and MRI facilities contributed significantly to diagnostic delays in multiple sclerosis (MS), a retrospective study showed.
In a sample of nearly 8,300 patients... -
Fight Continues Against Trump Administration Changes to 340B Drug Discount Program
(MedPage Today) -- The federal government's 340B program, which provides deeply discounted drugs to hospitals that serve low-income patients, continues to be a source of controversy for hospitals and drug companies.
Earlier this month, the American... -
Second-Season RSV Immunization Worked for Eligible Children
(MedPage Today) -- WASHINGTON--Real-world data backed the effectiveness of second-season nirsevimab (Beyfortus) immunizations against hospitalizations for children at high risk for severe respiratory syncytial virus (RSV) illness.
In the case...
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