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U.S. Candidate Risk Score Prioritizes Sicker Heart Transplant Candidates
FRIDAY, Oct. 23, 2026-- A U.S.-Candidate Risk Score (US-CRS) prioritizes sicker heart transplant candidates with higher mortality without transplant compared with the current medical urgency status, according to a study published online Oct. 12 in... -
Patient-Reported Outcomes Worse for Patients With RA Discontinuing TNF Inhibitor
FRIDAY, Oct. 23, 2026-- For patients with rheumatoid arthritis (RA), patient-reported outcomes (PROs) generally worsen shortly after tumor necrosis factor inhibitor (TNFi) discontinuation, according to a study published in the September issue of... -
Treating Depression in Pregnancy Influences Infant Brain Development
FRIDAY, Oct. 23, 2026 -- Treating depression with interpersonal psychotherapy during pregnancy influences infant brain development and early emotional function, according to a study published online Oct. 16 in Nature Medicine.
Catherine H. Demers... -
Remission Achievable With Usual Care for Axial Spondyloarthritis
FRIDAY, Oct. 23, 2026 -- For patients with axial spondyloarthritis (axSpA), remission is attainable with usual care, according to a study published in the September issue of the Journal of Rheumatology.
Franziska Kluempers, M.D., from... -
Outcomes Similar for Drug-Coated Balloon, Drug-Eluting Stent in PCI for De Novo Coronary Disease
FRIDAY, Oct. 23, 2026 -- For patients with de novo coronary artery disease undergoing percutaneous coronary intervention (PCI), drug-coated balloon (DCB) and drug-eluting stent (DES) strategies are comparable in terms of cardiovascular death and... -
Once-Daily Oral Icotronkinra Outperforms Placebo in Ulcerative Colitis
FRIDAY, Oct. 23, 2026 -- For patients with moderately to severely active ulcerative colitis, oral icotrokinra, a peptide that blocks the interleukin-23 receptor, yields a clinical response at week 12 significantly more often than placebo, according... -
DOACs Beneficial for Patients With A-Fib and Prior Intracranial Bleeding
FRIDAY, Oct. 23, 2026 -- For patients with atrial fibrillation (AF) and prior intracranial bleeding, direct oral anticoagulants (DOACs) are associated with a reduced risk for ischemic stroke (IS) and death, without an increased risk for intracranial... -
UEG: Disability Burden for Alcohol-Related Cirrhosis, Heart Failure Identified
THURSDAY, Oct. 22, 2026-- Western Europe has the highest disability burden associated with alcohol-related cirrhosis complicated by heart failure, according to a study presented at UEG Week, the annual meeting of United European Gastroenterology... -
Prevalence of Binge Eating 40.5 Percent in U.S. High School Students
THURSDAY, Oct. 22, 2026-- The prevalence of binge eating at least one day in the past 30 days is 40.5 percent in U.S. high school students, according to a study published online Oct. 15 in Morbidity and Mortality Weekly Report.Ryan Saelee, Ph.D... -
Early Uptake Was Rapid for Oral Semaglutide Relative to Injectables
THURSDAY, Oct. 22, 2026-- Early uptake was rapid for oral semaglutide (Wegovy pill) relative to injectable incretin-based weight management therapies, according to a study published online Oct. 13 in Annals of Internal Medicine.Yara Jelwan, M.D... -
Initiating Vasopressin at Lower Threshold Does Not Reduce Septic Shock Mortality
THURSDAY, Oct. 22, 2026-- A strategy recommending initiation of vasopressin at a lower dose of other vasopressors does not reduce 28-day mortality for patients in septic shock, according to a study published online Oct. 14 in the Journal of the... -
Cardiovascular Consequences of Continued Anabolic-Androgenic Steroid Use Identified
THURSDAY, Oct. 22 2026-- Continued anabolic-androgenic steroid (AAS) use is associated with sustained left ventricular (LV) hypertrophy, LV systolic dysfunction, and worsening diastolic function, which is reversible after discontinuation of AAS... -
Medical Device Adverse Event Reports Often Incomplete, Inaccurate
THURSDAY, Oct. 22, 2026-- Medical device adverse event reports are frequently incomplete, inaccurate, and delayed, according to a study published online Oct. 14 in The BMJ.Alyssa Zhou, from the University of California, San Francisco, and... -
Early Rhythm Control Beneficial for Patients With A-Fib, Stroke
THURSDAY, Oct. 22, 2026 -- For patients with atrial fibrillation (AF) and acute ischemic stroke, early initiation of rhythm control is associated with a lower risk for recurrent stroke or systemic embolism (SE), according to a study published online... -
AHA: Risk for Falls Elevated in Older Adults With Masked Hypertension
THURSDAY, Oct. 22, 2026 -- Masked hypertension (higher home than office blood pressure [BP]) is associated with a higher risk for falls in older adults, according to a study presented at the American Heart Association Hypertension Scientific... -
Adults With Type 1 Diabetes More Likely to Have Depressive, Anxiety Symptoms
THURSDAY, Oct. 22, 2026 -- Adults with type 1 diabetes have a higher prevalence of depressive and generalized anxiety disorder (GAD) symptoms than those with type 2 diabetes or without diabetes, according to a research letter published online Oct... -
AACR: Rural Populations Have Higher Breast Cancer Mortality
THURSDAY, Oct. 22, 2026 -- Rural populations experience higher breast cancer mortality, and the rural-urban gap is expected to widen by 2035, according to a study presented at the American Association for Cancer Research Conference on The Science of... -
HbA1c, Weight Increases Seen After Antipsychotic Initiation
WEDNESDAY, Oct. 21, 2026-- Antipsychotic treatment initiation is associated with rapid increases in hemoglobin A1c (HbA1c) and weight, according to a study published in the November issue of The Lancet Psychiatry.Juan Carlos Bazo-Alvarez, Ph.D... -
Some Benefits Found for GLP-1 Receptor Agonists in Older Adults With MASLD
WEDNESDAY, Oct. 21, 2026-- For older adults with metabolic dysfunction-associated steatotic liver disease (MASLD), glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatment is associated with lower risks for hepatic decompensation... -
Recommendations Updated for Management of Tinnitus
WEDNESDAY, Oct. 21, 2026 -- Updated recommendations are presented for the management of tinnitus in a clinical practice guideline issued by the American Academy of Otolaryngology-Head and Neck Surgery Foundation and published online Oct. 12 in... -
CGM Beneficial for Adults With Type 2 Diabetes Not on Insulin
WEDNESDAY, Oct. 21, 2026 -- Continuous glucose monitoring (CGM) leads to a greater reduction in glycated hemoglobin (HbA1c) levels than routine care for adults with type 2 diabetes not treated with insulin, according to a study published online Oct... -
AAO: Sequential NAION Occurs Earlier With GLP-1 Receptor Agonist Exposure
WEDNESDAY, Oct. 21, 2026 -- For patients with non-arteritic anterior ischemic optic neuropathy (NAION), glucagon-like peptide-1 (GLP-1) receptor agonist exposure is associated with earlier sequential NAION, according to a study presented at the... -
AAO: Association Between GLP-1 Receptor Agonists and AMD Explored
WEDNESDAY, Oct. 21, 2026 -- Crude odds ratios suggest an increased risk for age-related macular degeneration (AMD) in association with glucagon-like peptide-1 receptor agonist (GLP-1 RA) use, but this finding is reversed after adjustment for... -
AACR: Younger Adults Less Likely to Have Discussed CRC Screening With Clinician
WEDNESDAY, Oct. 21, 2026 -- Newly eligible younger adults are less likely to have discussed colorectal cancer (CRC) screening with their clinician compared with their older counterparts, according to a study published online Oct. 18 in the Journal... -
AAO: Deep Learning Using Fundus Photograph Predicts Myopia Progression
TUESDAY, Oct. 20, 2026-- A deep learning algorithm analyzing one fundus photograph can predict progression to moderate or high myopia, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held Oct. 9 to 12... -
Patient, Nurse Outcomes Worse With For-Profit Hospital Status
TUESDAY, Oct. 20, 2026-- For-profit hospital status is associated with worse patient and nurse outcomes, which is partially accounted for by differences in nurse staffing, according to a study published online Sept. 3 in Medical Care.Matthew D... -
ANA: Low Vitamin D Use in Patients on Enzyme-Inducing Antiseizure Drugs Raises Concerns
TUESDAY, Oct. 20, 2026-- Enzyme-inducing antiseizure drugs (ASDs) are associated with increased odds of incident osteoporosis or osteopenia, but vitamin D supplementation is underutilized, according to a study presented at the annual meeting of... -
ASCO: Breast Cancer Survival Inferior in Small Metropolitan, Nonmetropolitan Areas
TUESDAY, Oct. 20, 2026-- For women with breast cancer, survival is inferior in rural areas, and decreases in mortality rates are slower in rural areas for cancers amenable to early detection, according to two studies presented at the annual... -
Odds of Wolff-Parkinson-White Syndrome Increased With High Lithium Exposure
TUESDAY, Oct. 20, 2026-- Children living in areas with higher levels of lithium in drinking water are more likely to be diagnosed with Wolff-Parkinson-White (WPW) syndrome, according to a study published online Oct. 13 in the Journal of Clinical... -
UEG: Antibiotic Use From Preadolescence Linked to IBS Risk at Age 24 Years
TUESDAY, Oct. 20, 2026-- Antibiotic use from preadolescence through early adulthood is associated with an increased risk for irritable bowel syndrome (IBS), according to a study presented at UEG Week, the annual meeting of United European... -
Spatial Frequency Domain Imaging Offers Noninvasive Measure in Systemic Sclerosis
TUESDAY, Oct. 20, 2026-- For patients with systemic sclerosis, spatial frequency domain imaging (SFDI) provides a noninvasive measure of skin involvement that aligns with established assessments, according to a study published online Oct. 14 in... -
Favorable Long-Term Outcomes Seen With Treat-to-Target Strategy in Early RA
TUESDAY, Oct. 20, 2026-- For patients with early rheumatoid arthritis (RA) managed with a treat-to-target strategy, achievement of sustained remission at two years is associated with higher remission rates and better physical function at 10 years... -
Risk for Long COVID Increased With Autoimmune Rheumatic Diseases
TUESDAY, Oct. 20, 2026-- Patients with autoimmune rheumatic diseases (AIRD) have an increased risk for long COVID, according to a study published online Oct. 14 in Arthritis & Rheumatology.Namrata Singh, M.D., from the University of Washington... -
Cigarette Smoking in Living Kidney Donors Linked to Graft Loss
TUESDAY, Oct. 20, 2026-- For living kidney donors, cigarette smoking is associated with an increased risk for all-cause graft loss, according to a study published online Oct. 1 in Kidney360.Machi Kaneko McBee, M.D., from the University of... -
Benzodiazepine Use in Pregnancy Not Tied to Congenital Malformations
MONDAY, Oct. 19, 2026-- Benzodiazepine use in pregnancy is not associated with an increased risk for major congenital malformations, according to a study published online Oct. 13 in the Annals of Internal Medicine.Kelly Fung, from Brigham and... -
Evidence Shows Medical Cannabis Has Little Impact on Insomnia
MONDAY, Oct. 19, 2026-- For adults with insomnia, medical cannabis seems to have little to no clinically meaningful effect on quality of sleep, total sleep time, or daytime functioning, according to a study published online Oct. 13 in the Cochrane... -
Ultraprocessed Food Intake Linked to Adiposity, Vascular Brain Injury
MONDAY, Oct. 19, 2026 -- For middle-aged adults, higher ultraprocessed food (UPF) intake is associated with greater adiposity and greater odds of vascular brain injury (VBI), but not cognitive performance, according to a study published online Oct... -
Epilepsy Strongly Linked to Young-Onset Dementia
MONDAY, Oct. 19, 2026 -- Epilepsy is strongly associated with young-onset dementia (YOD; age younger than 65 years), according to a study published online Oct. 14 in Neurology.
Quentin Calonge, M.D., from Sorbonne Université in France, and... -
Automated Versus Handheld Ultrasound for Dense Breasts Yields Fewer Abnormal Interpretations
MONDAY, Oct. 19, 2026 -- For women with dense breasts, automated breast ultrasound (ABUS) is associated with fewer abnormal interpretations and fewer short-interval follow-up recommendations than handheld ultrasound (HHUS), with a similar cancer... -
No Association Found for Total Ultraprocessed Food Intake and Incident CRC
MONDAY, Oct. 19, 2026 -- For older U.S. adults, total ultraprocessed food (UPF) intake appears to not be associated with incident colorectal cancer (CRC), according to a study published online Oct. 15 in PLOS Medicine.
Leila Abar, Ph.D., from the... -
Global Incidence of Dementia Projected to Reach 24.7 Million by 2050
MONDAY, Oct. 19, 2026 -- The age- and sex-standardized dementia incidence is 9.7 per 1,000 person-years at risk, with higher incidence in women than men, according to a study published online Oct. 12 in JAMA Neurology.
Ashleigh S. Vella, Ph.D... -
Poorer Maternal Diet Quality Linked to Infantile Colic, Eczema
FRIDAY, Oct. 16, 2026-- Poorer maternal dietary quality is associated with infantile colic and eczema, according to a study published online Oct. 12 in JAMA Network Open.Emily Oken, M.D., M.P.H., from Harvard Medical School and Harvard Pilgrim... -
Adverse Family Outcomes Reported for Children With B-Cell ALL
FRIDAY, Oct. 16, 2026 -- Adverse family outcomes are reported in children with B-cell acute lymphoblastic leukemia (B-ALL), according to a study published online Oct. 13 in the Journal of the National Comprehensive Cancer Network.
Rozalyn L... -
Intermittent Hemodialysis Not Noninferior to Continuous Renal-Replacement Therapy
FRIDAY, Oct. 16, 2026-- Intermittent hemodialysis as an initial treatment approach is not noninferior to continuous renal-replacement therapy (CRRT) among critically ill patients with acute kidney injury (AKI) with indications for renal... -
Occupational Standing, Walking, Bending Linked to Risk for Miscarriage
FRIDAY, Oct. 16, 2026-- The risk for miscarriage is increased in association with occupational standing, walking, and forward bending, according to a study published online Oct. 6 in Occupational and Environmental Medicine.Hannah Nørtoft Frankel... -
Demographic, Tumor Factors Linked to Delays in Breast Cancer Care in Young Women
FRIDAY, Oct. 16, 2026-- Demographic and tumor factors are associated with delays in care for young women with breast cancer, but these delays do not influence outcomes, according to a study published online Oct. 12 in Cancer.Bessie X. Zhang, M.D... -
High Viral Suppression Found for Patients With HIV Receiving Long-Acting LEN/CAB
FRIDAY, Oct. 16, 2026-- Among patients with HIV who received long-acting lenacapavir (LEN)/cabotegravir (CAB), those with baseline viral suppression (VS) maintained VS and those without achieved VS by 13 weeks, according to a research letter... -
Imaging-Based Modalities Compared for Identifying At-Risk MASH
FRIDAY, Oct. 16, 2026-- FibroScan-aspartate aminotransferase (FAST) demonstrated the highest sensitivity for ruling out at-risk metabolic dysfunction-associated steatohepatitis (MASH), according to a study published in the October issue of the... -
1990 to 2023 Saw Increase in Global Burden of Acne
THURSDAY, Oct. 15, 2026-- The global burden of acne increased from 1990 to 2023 and is set to continue increasing through 2050, according to a study published online Oct. 14 in JAMA Dermatology.Pierina Parraga, from Brigham and Women's Hospital in... -
Structured Support May Attenuate Weight Gain After GLP-1 RA Cessation
THURSDAY, Oct. 15, 2026-- Structured support may attenuate weight gain after cessation of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), according to a study published online Oct. 7 in Obesity Science and Practice.Kelseanna Hollis‐Hansen...
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