(MedPage Today) -- Although most observers agree that the No Surprises Act did fix one problem--nixing unexpected bills for out-of-network care--lawmakers are still trying to fix other problems caused by the law.
The act, passed at the...
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-
Congress Mulls Ways to Fix the Surprise Billing Law
-
Fenebrutinib May Curb Chronic Active Lesions in Multiple Sclerosis
(MedPage Today) -- The investigational Bruton's tyrosine kinase (BTK) inhibitor fenebrutinib may curb chronic active lesions in multiple sclerosis (MS), data from phase III trials suggested.
Two MRI biomarkers in MS are slowly expanding lesions... -
Lyme Disease Vaccine Candidate Just Misses Its Mark in Late-Stage Trial
(MedPage Today) -- WASHINGTON--An investigational Lyme disease vaccine covering six serotypes across four Borrelia species had a vaccine efficacy (VE) rate of over 70%, but it just missed a preset noninferiority threshold, a placebo-controlled... -
AI May Help Detect Rare Sperm in Men With Azoospermia
(MedPage Today) -- BALTIMORE--An artificial intelligence (AI)-powered tool could be a last resort for couples wanting to conceive a biological child who had been told they have no sperm, researchers said.
The Sperm Tracking and Recovery (STAR... -
RFK Jr.'s Claim That Arabs 'Don't Produce Science' Meets a Nobel Prize Reality Check
(MedPage Today) -- Health and Human Services (HHS) Secretary Robert F. Kennedy Jr.'s broad assertions about Arab contributions to humanity's scientific and literary discoveries at a Republican campaign event in Grand Rapids, Michigan, have drawn... -
Novel HDAC Inhibitor Hits Main Goal in Unresectable Melanoma Trial
(MedPage Today) -- Progression-free survival (PFS) in unresectable melanoma improved significantly with the addition of an investigational histone deacetylase (HDAC) inhibitor to immunotherapy, a randomized trial showed.
Median PFS increased from... -
Certain Myasthenia Gravis Patients May Need More Time to Respond to Efgartigimod
(MedPage Today) -- Intravenous efgartigimod (Vyvgart) continued to show efficacy and safety in patients with generalized myasthenia gravis who did not have detectable anti-acetylcholine receptor (AChR) antibodies, according to open-label data from... -
Bid to Block GLP-1 Ads Denied; First Weekly Insulin for T2D in Kids; Fertility Fell
(MedPage Today) -- A U.S. judge rejected Novo Nordisk's request to temporarily block Eli Lilly from running advertisements claiming its weight-loss and diabetes drugs are more powerful. (Reuters via AOL)
The FDA expanded the approval for insulin... -
Head Shape and Alzheimer's; Prenatal Choline and Kids' IQ; Aspirin and Dementia
(MedPage Today) -- Can head shape influence Alzheimer's disease pathology? (Alzheimer's & Dementia)
The newly launched AD-Smart Alzheimer's disease platform trial will test repurposed drugs in the U.K., starting with the diabetes drug metformin... -
Live Webinar October 29: Should We Let Robots Be Doctors?
(MedPage Today) -- While some major medical organizations like the American Medical Association (AMA) have adopted policies relegating artificial intelligence (AI) to an assistive rather than autonomous role in healthcare, bioethicist and oncologist... -
Cardiologist-Prime Minister? LDL Pill Eyed for Diabetes; Second Tricuspid TEER OK'd
(MedPage Today) -- Cardiologist Ilija Srdanović, MD, PhD, is among the student-backed leaders in Serbia that won the country's snap parliamentary election. Some expect him to be the new prime minister. (Nacionale)
The CETP inhibitor obicetrapib... -
Trial Results Show 'Something We Have Not Seen for Years' in Osteosarcoma
(MedPage Today) -- The investigational antibody-drug conjugate (ADC) risvutatug rezetecan (Ris-Rez) significantly improved progression-free survival (PFS) in patients with relapsed or refractory osteosarcoma, the phase III ARTEMIS-011 trial from... -
ADA Says Protest 'Threat' Heightened Security Concerns at Meeting
(MedPage Today) -- In a reversal of its original findings, the American Diabetes Association (ADA) said members who were kicked out of its annual meeting in June did not violate its code of conduct.
Instead, the final report of its governance... -
Elizabeth Holmes: Master of Deception or Victim of Coercion?
(MedPage Today) -- I wasn't planning to see Nathan Fielder and Lance Oppenheim's movie about Elizabeth Holmes, "You Can See Everything." What truth would I learn? Holmes has every reason to try to rehabilitate her image, and I'm used to working... -
Pneumococcal Vaccine Candidate Targeting 25 Serotypes Advances
(MedPage Today) -- WASHINGTON--A pneumococcal conjugate vaccine (PCV) covering 25 serotypes was safe and generated immune responses among infants that were comparable to the current 20-valent vaccine (Prevnar 20), a phase II trial showed.... -
Congo's Ebola Outbreak Tops 10,000 Cases as Authorities Race to Slow the Spread
(MedPage Today) -- The fast-moving Ebola outbreak in Congo has reached 10,000 confirmed cases, government data showed Tuesday, as health authorities race to slow the spread of the disease in multiple African countries.
It is the fastest-growing... -
Targeted Doublet Improves Survival in MET-Positive Progressive Lung Cancer
(MedPage Today) -- Patients with MET-altered advanced non-small cell lung cancer (NSCLC) lived significantly longer with a targeted combination after progression on standard-of-care osimertinib (Tagrisso), a large randomized trial showed.
Median... -
'The Pitt' Actor Named Sexiest Man; CDC Deputy Director Exits; Vaccine Limbo
(MedPage Today) -- Note that some links may require registration or subscription.
Actor Noah Wyle, who played an emergency department physician in "The Pitt" and "ER," was named People's Sexiest Man Alive.
Jennifer Shuford, MD, MPH, the CDC's... -
Menopausal Hormone Therapy May Boost GLP-1 Weight Loss
(MedPage Today) -- Menopausal women taking hormone therapy in addition to a GLP-1 medication may see greater and sustained weight loss, a retrospective cohort study suggested.
Women taking semaglutide (Wegovy) and menopausal hormone therapy had... -
Obesity in Young Adults Linked to Multiple Early Cancers
(MedPage Today) -- Obesity in young adulthood was associated with significantly increased likelihood of early-onset cancers, with the risk persisting into middle age, a large population-based study from South Korea showed.
The 10-year cumulative... -
AI Scribes Improved Note-Taking Time but Not Productivity, Study Finds
(MedPage Today) -- The use of an artificial intelligence (AI)-driven ambient scribe in outpatient practice was associated with reductions in time spent taking notes and increased note length, but other productivity measures were largely unchanged... -
GLP-1s Tied to Lower Rates of MS Relapse Activity, Real-World Study Shows
(MedPage Today) -- Multiple sclerosis (MS) patients exposed to a GLP-1 receptor agonist had lower rates of relapse activity and steroid use, reduced incidence of optic neuritis, and fewer demyelinating events compared with those who didn't use... -
She Voted for Trump Every Time. Then Came Cancer and the Bills.
(MedPage Today) -- The Ford Expedition rumbled to a stop and Cindy Banda's bedazzled flip-flops landed on the asphalt of the Houston cancer center's vast parking lot. She threaded through the rows of cars, a tally of patients who gather here to... -
Study Questions Safety of Strict Protein Restriction in Chronic Kidney Disease
(MedPage Today) -- DENVER--Strict dietary protein restriction was associated with worse clinical outcomes in patients with chronic kidney disease (CKD) who were not dependent on dialysis, a South Korean prospective cohort study suggested.... -
High-Dose Vitamin D Fails to Improve Survival in Dialysis Patients
(MedPage Today) -- DENVER--Supplementation with high-dose cholecalciferol (vitamin D3) did not improve overall survival in patients receiving dialysis for end-stage kidney disease, according to findings from the SIMPLIFIED trial.
Overall survival... -
'Magic Drug' Reduces Risk of Death by 44% in Lung Cancer Trial
(MedPage Today) -- A next-generation KRAS G12C inhibitor significantly improved survival outcomes versus first-generation drugs for previously treated advanced or metastatic non-small cell lung cancer, a phase III trial showed.
Median progression... -
Low-Dose Naltrexone Linked to Some Long COVID Improvements
(MedPage Today) -- WASHINGTON--People with long COVID reported significantly better functioning and symptom improvements after taking low-dose naltrexone, according to a small retrospective cohort study.
Symptom burdens declined among 230... -
Baby Aspirin Misses Mark for Primary Cardiovascular Prevention in CKD
(MedPage Today) -- DENVER--Daily low-dose aspirin did not significantly reduce major vascular events in adults with chronic kidney disease (CKD), the randomized ATTACK trial showed.
Over a mean follow-up of 3.1 years, 2.4% of adults with CKD... -
Lower Metastasis Risk in Very High-Risk Prostate Cancer With Intensified Treatment
(MedPage Today) -- Men with very high-risk prostate cancer had a significantly lower risk of metastasis when they received darolutamide (Nubeqa) in addition to androgen deprivation therapy (ADT) and radiation therapy (RT), a randomized trial showed... -
GLP-1s May Interact With Psychiatry Medication, Case Report Suggests
(MedPage Today) -- During an appointment with her psychiatrist, a 50-year-old woman with bipolar disorder reported new symptoms of tremor in both hands, slurred speech, and blurred vision.
She was taking lithium, but 3 weeks prior, she had also... -
GLP-1s May Interact With Psychiatry Medication
(MedPage Today) -- During an appointment with her psychiatrist, a 50-year-old woman with bipolar disorder reported new symptoms of tremor in both hands, slurred speech, and blurred vision.
She was taking lithium, but 3 weeks prior, she had also... -
Prior Authorization Denied
(MedPage Today) -- Is it just me or has the process of getting prior authorization for our patients' prescriptions and procedures gotten more onerous?
Over the past few years, our practice has developed amazing systems to help smooth the road... -
How Daylight Saving Time Changes Affect You and What You Can Do About It
(MedPage Today) -- An extra hour of sleep is on the way for most Americans, though the "fall back" to standard time will bring darker afternoons, too.
One tip: Try to get outside for some morning sun--it'll help your body clock reset faster... -
Bon Secours agrees $5.7bn takeover of Bain-backed Surgery Partners
via HealthcareUS hospital chain is the latest not-for-profit healthcare provider to strike a large deal -
Novel Drug Doubles PFS in Heavily Pretreated, HR-Positive Breast Cancer
(MedPage Today) -- Patients with heavily pretreated hormone receptor (HR)-positive breast cancer lived twice as long without disease progression with the novel antibody-drug conjugate (ADC) izalontamab brengitecan (iza-bren), a randomized trial... -
Nurse Killed in Attack; Orthopedist's Drug Charges; Lung Cancers in Non-Smokers
(MedPage Today) -- Note that some links may require registration or subscription.
A nurse was killed and a health worker severely injured after being attacked while responding to an Ebola alert in Congo, according to the World Health Organization... -
Remibrutinib Cuts Multiple Sclerosis Relapse Rates in Phase III Trials
(MedPage Today) -- Twice daily oral doses of 100 mg of the Bruton's tyrosine kinase (BTK) inhibitor remibrutinib reduced relapses more than teriflunomide (Aubagio) in patients with relapsing multiple sclerosis (MS), data from two identical phase... -
'The Cat Is Out of the Bag': What We Heard This Week
(MedPage Today) -- "The cat is out of the bag."--Adam Waickman, PhD, of SUNY Upstate Medical University in Syracuse, New York, discussing the large dengue outbreaks in Florida and warning of further spread across the U.S.
"It's an open question... -
Trio of IgA Nephropathy Drugs Proves Mettle in Interim Analyses
(MedPage Today) -- DENVER--Significant proteinuria reductions were reported in phase III interim analyses assessing two investigational IgA nephropathy agents and a third that was recently granted accelerated approval.
First, in the RAINIER... -
A Win for Durvalumab Doublet in Muscle-Invasive Bladder Cancer
(MedPage Today) -- Perioperative treatment with durvalumab (Imfinzi) plus neoadjuvant enfortumab vedotin (EV) significantly improved event-free survival (EFS) and overall survival (OS) compared with radical cystectomy in patients with muscle-invasive... -
Bon Secours nears $6bn takeover of Bain-backed Surgery Partners
via HealthcareUS hospital chain is the latest not-for-profit healthcare provider to seek a large deal -
Medicare Will Pay $50k for Your Heart Attack. It Should Pay $100 to Prevent It.
(MedPage Today) -- We are currently in a "golden age of medical science," yet in a "dark age of healthcare delivery." An important illustration is the diagnosis and treatment of America's number one cause of death and disability, coronary artery... -
Execution Staff Warned That Christa Pike's IV Site Might Have 'Blown'
(MedPage Today) -- Tennessee execution team members failed multiple times to establish working IV lines in Christa Pike's arms before her attempted execution and warned that some of her veins may have ruptured, or "blown," before she was injected... -
Another Unprecedented OS Win in Extensive-Stage SCLC With Tarlatamab Maintenance
(MedPage Today) -- Overall survival (OS) in extensive-stage small-cell lung cancer (ES-SCLC) approached 2 years with tarlatamab (Imdelltra) combination maintenance therapy after first-line chemoimmunotherapy, a large randomized trial showed.
Median... -
SGLT2 Inhibitors Tied to Uptick in Hemoglobin and Hematocrit
(MedPage Today) -- DENVER--Treatment with SGLT2 inhibitors was linked with modest but statistically significant increases in hemoglobin and hematocrit levels across a broad spectrum of patient populations, according to a systematic review and... -
Many care services in England have never been inspected by regulator
via HealthcareBacklog of assessment calls into question Andy Burnham’s vow to fix the ‘broken’ system -
Many care homes in England have never been inspected by regulator
via HealthcareBacklog of assessment calls into question Andy Burnham’s vow to fix the ‘broken’ system -
Tovecimig-Based Doublet Boosts Response and PFS in Advanced Biliary Tract Cancer
(MedPage Today) -- Investigational tovecimig combined with paclitaxel significantly improved the response rate and progression-free survival (PFS) in patients with previously treated advanced or metastatic biliary tract cancer, according to the... -
Novel ADC Achieves Impressive PFS Advantage in HER2-Low Metastatic Breast Cancer
(MedPage Today) -- Patients with recurrent or metastatic HER2-low breast cancer had dramatic improvement in progression-free survival (PFS) when treated with a novel antibody-drug conjugate (ADC) targeting HER2, a large randomized trial showed... -
Patient Death Reported in Multiple Sclerosis CAR-T Study
(MedPage Today) -- The investigational CD19-directed chimeric antigen receptor (CAR) T-cell therapy zolacabtagene autoleucel (zola-cel) showed the potential to treat people with highly active relapsing multiple sclerosis (MS) and progressive MS...
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