(MedPage Today) -- Antithrombotic monotherapy was similar to dual antiplatelet therapy (DAPT) for 6-month outcomes after left atrial appendage (LAA) closure, the SIMPLAAFY trial showed.
The incidence rate of combined all-cause death, stroke, systemic...
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-
Is It Over for DAPT After Left Atrial Appendage Closure?
-
Alzheimer's Study Tracks Faster Tau Buildup in Younger Patients
(MedPage Today) -- People with early-onset Alzheimer's disease had faster and more severe accumulation of tau than those whose Alzheimer's symptoms started after age 65, imaging data showed.
Compared with older Alzheimer's patients, tau burden... -
U.S. on the Verge of Forfeiting Major Public Health Victory on Measles
(MedPage Today) -- International health experts are meeting this week to determine if the U.S. and Mexico have forfeited one of their greatest public health victories--the elimination of measles.
Measles is one of the most contagious diseases... -
Trump's FDA Pick on Thin Ice; AI to Fight Insurance Denials; Coffee and Gut Health
(MedPage Today) -- Note that some links may require registration or subscription.
Doubts have emerged among Senate Republicans about Heidi Overton, MD, PhD, President Trump's pick to run the FDA, just days before a key vote on her nomination by... -
Major Change to Prostate Cancer Screening Guidelines
(MedPage Today) -- Shifting gears on prostate cancer screening, the American Cancer Society (ACS) now recommends screening with prostate-specific antigen (PSA) every 2 years for average-risk men ages 50 to 69.
Since the release of its previous... -
Prescriptions Down 25%, Overdoses Cut in Half: What Stopped a Gabapentinoid Surge?
(MedPage Today) -- High-profile media coverage of the harms associated with the gabapentinoid pregabalin (Lyrica) and tighter safeguards coincided with fewer prescriptions and overdoses in Australia, a retrospective study showed.
Following a media... -
MD Defends 'The Pitt'; Dr. Glaucomflecken Talks Surprise Billing; Holiday Health PSA
(MedPage Today) -- The following contains links to social media websites including Bluesky, X, TikTok, Instagram, Facebook, and LinkedIn.
"You can't copyright the emergency room." An emergency physician defended the originality of "The Pitt,... -
Trump Officials Will Fund New Research on Controversial Psychedelic Drug Ibogaine
(MedPage Today) -- Federal officials on Thursday announced new funding to explore the medical potential of ibogaine, a controversial psychedelic drug championed by veterans, conservative lawmakers, and podcasters aligned with President Donald Trump... -
Response to Standard PBC Treatment at 1 Year Linked to Lower Long-Term Risks
(MedPage Today) -- A biochemical response to ursodeoxycholic acid (UDCA) at 12 months was associated with lower 5-year risks of hepatic decompensation and mortality in patients with primary biliary cholangitis (PBC), a propensity-matched landmark... -
Advances and Unmet Needs in Pediatric Sickle Cell Disease
(MedPage Today) -- As the 1970s came to a close, sickle cell disease (SCD) remained largely a pediatric condition because few children born in the U.S. with the condition survived to adulthood. Today, about 95% of children born with SCD in developed... -
Another Promising Study on Statins in Compensated Cirrhosis
(MedPage Today) -- Statin initiation among adults with compensated cirrhosis was associated with a lower risk of hepatic decompensation and lower overall mortality, according to a large observational study.
Among over 18,000 patients, the cumulative... -
Managing Metastases in Advanced Prostate Cancer
(MedPage Today) -- In "Beyond Diagnosis: Metastatic Castration-Sensitive Prostate Cancer," Cleveland Clinic oncologist Christopher Wee, MD, and host John Mangels discuss how clinicians can guide patients through the growing complexities of treatment... -
Senators Investigate Whether RFK Jr. Lied to Congress About Samoa Trip
(MedPage Today) -- Two Democratic senators are launching an investigation into whether Health Secretary Robert F. Kennedy Jr. lied to Congress about his reason for a 2019 trip to Samoa after the Associated Press and the Guardian published documents... -
Doctor Behind Mass Shooting in D.C., Police Say
(MedPage Today) -- Police named emergency physician Matt Lambert, MD, as the gunman in Thursday's mass shooting in Washington, D.C.
According to police, Lambert fatally shot a man at a gym and left another in critical condition before fleeing... -
Nurse Broke Kid's Rib? Doc Accused of Illegal Pics; Quest's $13M Giants Tickets
(MedPage Today) -- Daniel Keate, a pediatric nurse in Kentucky, was arrested on domestic violence charges, including an allegation that he squeezed a 5-year-old family member so hard it broke her rib. (The News-Enterprise)
Families of 13 children... -
Reflux Drugs and Dementia Risk; Epstein-Barr's Link to IBD; Managing Hepatitis Delta
(MedPage Today) -- Use of proton pump inhibitors in older adults was associated with a modestly increased risk of incident dementia, according to a meta-analysis of nearly two dozen studies published in Clinical Pharmacology and Therapeutics.... -
Novel GLP-1 Cut Heavy Drinking Days in Alcohol Use Disorder
(MedPage Today) -- The investigational glucagon/GLP-1 dual receptor agonist pemvidutide significantly reduced the number of heavy drinking days (HDDs) per week in patients with moderate-to-severe alcohol use disorder (AUD), the phase II RECLAIM... -
Novel Sjogren's Drug Passes First Phase III Test
(MedPage Today) -- ORLANDO--An investigational CD40L antagonist called dazodalibep looks to be nearing the finish line on the way to approval for Sjögren's disease, based on results from a 48-week phase III trial reported here.
With scores... -
Perioperative Therapy Tops Prostatectomy Alone in High-Risk Prostate Cancer
(MedPage Today) -- Results from a substudy of the phase III PROTEUS trial presented at the European Society for Medical Oncology (ESMO) congress showed that adding apalutamide (Erleada) and androgen-deprivation therapy (ADT) before and after radical... -
Kate Middleton's Cancer; RFK Jr. and 'Lavish Gifts'; Medicare Eligibility at Age 50?
(MedPage Today) -- Note that some links may require registration or subscription.
Kate Middleton, the Princess of Wales, said spending time with nature has been part of her cancer recovery. (USA Today)
Former FDA Commissioner Marty Makary, MD... -
GLP-1 Drugs Linked to Improved Survival After Liver Transplant
(MedPage Today) -- Liver transplant patients who took a GLP-1 receptor agonist had a lower risk of death than those who weren't on a GLP-1 drug, according to a retrospective three-center cohort study.
Among 2,402 patients, those on GLP-1 receptor... -
Upfront PCI Still Not Beneficial for Stable CAD as Far Out as 25 Years
(MedPage Today) -- A longer horizon did not give patients with stable coronary artery disease (CAD) any improved hard outcomes when getting an invasive strategy over conservative management, according to extended results from the COURAGE and ISCHEMIA... -
Anticoagulants Reign Supreme in VTE Prevention After Joint Replacement
(MedPage Today) -- Aspirin didn't prevent venous thromboembolism (VTE) as well as anticoagulants did for patients undergoing elective hip or knee replacements, the randomized PEPPER trial showed.
For the primary composite endpoint of death from... -
Last Batch of New Residency Spots Doled Out by CMS
(MedPage Today) -- As the Centers for Medicare & Medicaid Services (CMS) doled out the final 200 of an additional 1,000 residency positions created by Congress 5 years ago, medical groups called for more federally funded spots to mitigate workforce... -
Ibuprofen and Kidney Injury: Study Reveals Who Is Most at Risk
(MedPage Today) -- Use of ibuprofen was associated with higher rates of acute kidney injury (AKI) among hospitalized adults, but the excess risk was concentrated almost entirely in certain patients, according to a retrospective active-comparator... -
Biden Says He Wouldn't Have Run for a Second Term in 2024 If He Knew He Had Cancer
(MedPage Today) -- Joe Biden says he did not know he had cancer while he was president and would not have sought a second term if he already had been diagnosed.
The former Democratic president's comments came in an interview with People magazine... -
Cell Therapy for Knee Osteoarthritis Reverses Damage in Early Trial
(MedPage Today) -- ORLANDO--A cell-based therapy for knee osteoarthritis (OA) called OSCA not only improved patients' symptoms in a phase IIa trial and appeared safe, but also showed signs of reversing joint damage within a few months, a researcher... -
Is There Still a Place for Antibiotics in Modern Hidradenitis Suppurativa Treatment?
(MedPage Today) -- As treatment options for hidradenitis suppurativa (HS) continue to expand, one of the questions discussed at the European Academy of Dermatology and Venereology meeting in Vienna was how antibiotics can still be beneficial in... -
AI Suicide Lawsuit; School Phone Ban Results; Kudzu for Binge Drinking?
(MedPage Today) -- Google's artificial intelligence (AI) chatbot Gemini helped a 13-year-old girl prepare a suicide plan, according to a lawsuit in California that alleges the company released the chatbot knowing it could be dangerous. (The Hill... -
Impeach and Remove RFK Jr.
(MedPage Today) -- When the new Congress convenes on January 3, 2027, Secretary of HHS Robert F. Kennedy Jr. should be impeached by the House of Representatives and then removed by the Senate.
Can this be done? Yes. Although classically associated...
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