(MedPage Today) -- Now that the deadline has passed for an HHS vaccine task force to issue its report on the timing and sequencing of vaccines, public health advocates are concerned about what happens when the report eventually comes out.
"The...
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-
HHS Vaccine Task Force Misses Report Deadline
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Novel siRNA Therapeutic Cuts Liver Fat in MASLD, Early Trial Shows
(MedPage Today) -- One dose of a novel small interfering RNA (siRNA) therapy--CIDEBsiRNA (also known as ALN-CIDEB)--led to normal liver fat content and lower alanine aminotransferase (ALT) levels in most patients with metabolic dysfunction... -
Bioengineered Liver System Passes Safety Test in Phase I Trial
(MedPage Today) -- A single-use bioengineered liver paired with an extracorporeal blood circuit that replicates key functions of a human liver was shown to be safe among patients with syndromes of liver failure in a small phase I trial.
There... -
More Women on Testosterone; Hormone Patch Updates; Drug-Induced Bone Loss
(MedPage Today) -- Testosterone use among females has risen since 2016 and is frequently prescribed without a documented diagnosis of hypoactive sexual desire disorder, the sole evidence-based indication. (Journal of Clinical Endocrinology &... -
GLP-1 Pill Shows Benefit in Sleep Apnea
(MedPage Today) -- The oral GLP-1 receptor agonist orforglipron (Foundayo) improved sleep-disordered breathing in patients with moderate-to-severe obstructive sleep apnea and overweight or obesity, two phase III trials showed.
For the treatment... -
Billy Joel Back on Stage; Alzheimer's and Sleep; Predicting Parkinson's Progression
(MedPage Today) -- Musician and songwriter Billy Joel announced his first official show since his normal pressure hydrocephalus diagnosis. (People)
Topline results from a phase II study showed that treatment with investigational PGN-EDODM1 led... -
Another Option for Rare Benign Soft-Tissue Tumor Wins FDA Approval
(MedPage Today) -- The FDA approved the small-molecule inhibitor pimicotinib (Pimjetmi) for selected patients with symptomatic tenosynovial giant cell tumor (TGCT) and high surgical risk.
An oral selective inhibitor of colony stimulating factor... -
ADA Publications Chief Resigns
(MedPage Today) -- The vice president of publications at the American Diabetes Association (ADA) has resigned amid the ongoing boycott of the organization.
Christian Kohler, who was with the ADA for 22 years, expressed "profound disappointment... -
Next-Gen Anticoagulant Lands FDA Nod for Secondary Stroke Prevention
(MedPage Today) -- The FDA approved asundexian (Sunharbo) as the first factor XIa (FXIa) inhibitor for secondary stroke prevention, the agency announced on Monday.
Asundexian, an oral, direct, small-molecule inhibitor of FXIa, is indicated for... -
HEPA Filters for Blood Sugar; ECMO-Equipped EMS & CPR; Valve-in-Valve-in-Valve TAVR
(MedPage Today) -- A sham-controlled trial showed that sleeping while using high‑efficiency particulate air (HEPA) filters in the bedroom improved blood sugar control, as highlighted by NYU Langone Health.
A smartwatch artificial intelligence... -
Enfortumab Vedotin-Based Treatment Solidified for Muscle-Invasive Bladder Cancer
(MedPage Today) -- In this exclusive roundtable video from MedPage Today, three expert leaders in the field of bladder cancer discuss the latest emerging data presented at the European Society for Medical Oncology (ESMO) congress.Moderator Matthew... -
Cutaneous Sarcoidosis Could Soon Get an Effective Therapy
(MedPage Today) -- ORLANDO--Patients with cutaneous sarcoidosis--a condition with no very effective therapy--saw dramatic improvement with the dual-acting TYK2/JAK1 inhibitor brepocitinib (Lisraya) in a small phase II trial.
Patients... -
RFK Jr. Is Ushering in Peptides. As an Oncologist, Here Are My Concerns.
(MedPage Today) -- On July 13, 2025, at a Las Vegas hotel hosting the Revolution Against Aging and Death Festival, two women were taken away in ambulances. Both had received injections containing experimental peptides at a conference booth. Both... -
Another Drug Shows Potential for Functional Cures in Chronic Hepatitis B
(MedPage Today) -- Reductions in hepatitis B surface antigen (HBsAg) were observed with a novel small interfering RNA (siRNA) therapy in patients with chronic hepatitis B virus (HBV) infection, according to a phase II study.
Among patients randomized... -
Nanobody Shows Promise in Myasthenia Gravis
(MedPage Today) -- Results from the phase III PREVAIL trial presented at the American Association of Neuromuscular & Electrodiagnostic Medicine annual meeting showed that treatment with the investigational once-weekly nanobody gefurulimab significantly... -
CAR-T Therapy: Mixed Results in Rheumatoid Arthritis Trial
(MedPage Today) -- ORLANDO--Rheumatoid arthritis (RA) may not be as amenable to chimeric antigen receptor (CAR) T-cell therapy as has been the case in lupus and certain other autoimmune conditions, research presented here suggested.
Among... -
New Medicare Payment Model for Back Pain, Heart Failure Riles Docs
(MedPage Today) -- Physician groups are seeking a delay for a new Medicare demonstration model debuting January 1 that mandates doctors who treat low back pain and congestive heart failure (CHF) patients meet performance standards or face payment... -
Novel ADC Boosts Survival in Pretreated Endometrial Cancer
(MedPage Today) -- Results from the TroFuse-005 trial presented at the annual European Society for Medical Oncology congress showed that the investigational antibody-drug conjugate (ADC) sacituzumab tirumotecan (sac-TMT) significantly improved... -
Could an Independent Agency for Vaccine Safety Strengthen Public Trust?
(MedPage Today) -- Routinely used vaccines in the U.S. are very safe, but questions about potential adverse events still require thorough, credible investigations. Daniel Salmon, PhD, MPH, of the Johns Hopkins Bloomberg School of Public Health... -
Peak Stroke Risk Hours; Concerning Flu Signals; Can AI Make Men Open Up?
(MedPage Today) -- Note that some links may require registration or subscription.
The Washington Post reviewed the 3 hours--between 6 and 9 a.m.--when most strokes occur.
Fresh & Ready Foods LLC said 2,414 Fresh To You sausage, egg... -
AMA Steps Into the Debunking Ring
(MedPage Today) -- I've spent a lot of time writing about the importance of science communication, especially for physicians. I've also spent time publicly musing about the importance of our professional societies weighing in on the dangers of... -
CVS break-up shows how M&A-first strategy is not the healthiest option
via HealthcareDespite touting better customer outcomes as well as major financial benefits, its stock price has underperformed
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