(MedPage Today) -- An extra hour of sleep is on the way for most Americans, though the "fall back" to standard time will bring darker afternoons, too.
One tip: Try to get outside for some morning sun--it'll help your body clock reset faster...
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How Daylight Saving Time Changes Affect You and What You Can Do About It
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GLP-1 Drugs Linked to Improved Survival After Liver Transplant
(MedPage Today) -- Liver transplant patients who took a GLP-1 receptor agonist had a lower risk of death than those who weren't on a GLP-1 drug, according to a retrospective three-center cohort study.
Among 2,402 patients, those on GLP-1 receptor...
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Upfront PCI Still Not Beneficial for Stable CAD as Far Out as 25 Years
(MedPage Today) -- A longer horizon did not give patients with stable coronary artery disease (CAD) any improved hard outcomes when getting an invasive strategy over conservative management, according to extended results from the COURAGE and ISCHEMIA...
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Anticoagulants Reign Supreme in VTE Prevention After Joint Replacement
(MedPage Today) -- Aspirin didn't prevent venous thromboembolism (VTE) as well as anticoagulants did for patients undergoing elective hip or knee replacements, the randomized PEPPER trial showed.
For the primary composite endpoint of death from...
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Last Batch of New Residency Spots Doled Out by CMS
(MedPage Today) -- As the Centers for Medicare & Medicaid Services (CMS) doled out the final 200 of an additional 1,000 residency positions created by Congress 5 years ago, medical groups called for more federally funded spots to mitigate workforce...
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Ibuprofen and Kidney Injury: Study Reveals Who Is Most at Risk
(MedPage Today) -- Use of ibuprofen was associated with higher rates of acute kidney injury (AKI) among hospitalized adults, but the excess risk was concentrated almost entirely in certain patients, according to a retrospective active-comparator...
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Biden Says He Wouldn't Have Run for a Second Term in 2024 If He Knew He Had Cancer
(MedPage Today) -- Joe Biden says he did not know he had cancer while he was president and would not have sought a second term if he already had been diagnosed.
The former Democratic president's comments came in an interview with People magazine...
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Cell Therapy for Knee Osteoarthritis Reverses Damage in Early Trial
(MedPage Today) -- ORLANDO--A cell-based therapy for knee osteoarthritis (OA) called OSCA not only improved patients' symptoms in a phase IIa trial and appeared safe, but also showed signs of reversing joint damage within a few months, a researcher...
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Is There Still a Place for Antibiotics in Modern Hidradenitis Suppurativa Treatment?
(MedPage Today) -- As treatment options for hidradenitis suppurativa (HS) continue to expand, one of the questions discussed at the European Academy of Dermatology and Venereology meeting in Vienna was how antibiotics can still be beneficial in...
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AI Suicide Lawsuit; School Phone Ban Results; Kudzu for Binge Drinking?
(MedPage Today) -- Google's artificial intelligence (AI) chatbot Gemini helped a 13-year-old girl prepare a suicide plan, according to a lawsuit in California that alleges the company released the chatbot knowing it could be dangerous. (The Hill...
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Impeach and Remove RFK Jr.
(MedPage Today) -- When the new Congress convenes on January 3, 2027, Secretary of HHS Robert F. Kennedy Jr. should be impeached by the House of Representatives and then removed by the Senate.
Can this be done? Yes. Although classically associated...
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Novel Glucagon/GLP-1 Agonist Meets Cardiovascular Safety Endpoint
(MedPage Today) -- Survodutide, an investigational glucagon receptor and GLP-1 receptor dual agonist, was safe for patients with obesity and either established cardiovascular disease (CVD), chronic kidney disease (CKD), or increased risk of CVD...
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Don't Overlook Cancer Risks in People With HIV, Experts Say
(MedPage Today) -- Preventing and screening for common cancers seen in the general population should be a key component of HIV care, experts said at the recent IDWeek annual meeting.
Given cancer risks, "prevention becomes a key part of HIV care...
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Assessing and Managing HIV's Higher Heart Disease Risks
(MedPage Today) -- Understanding how HIV can shape cardiovascular disease risk may help clinicians tailor care to patients' needs, which starts with statins for most adults with HIV.
"HIV holds its own as a risk factor for developing cardiovascular...
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After CAR-T Failure in Diffuse Large B-Cell Lymphoma, What Comes Next?
(MedPage Today) -- CD19-targeted chimeric antigen receptor (CAR) T-cells have emerged as a second- and later-line treatment strategy for patients with diffuse large B-cell lymphoma (DLBCL), with three FDA-approved products.
"Across CAR T-cell...
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What the VA Gets Right About Death
(MedPage Today) -- On November 11, 1991, I called my father, a taciturn 24-year senior non-commissioned officer, to wish him a happy Veterans Day. I was a newly minted second lieutenant, and his pride in my becoming an officer and first-generation...
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RFK Jr.'s New Power Play; MAHA Defends Russell Brand; USPSTF COI Storm
(MedPage Today) -- HHS Secretary Robert F. Kennedy Jr., who was thought only recently to be possibly on his way out, now may be making new alliances in the post-midterm White House. (Washington Sun)
Kennedy also said that Senate Republicans who...
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Ex-FDA Chief Saw 'Corruption'; RFK Jr.'s Power Play; MAHA Defends Russell Brand
(MedPage Today) -- Former FDA chief Marty Makary, MD, MPH, accused the White House and HHS aides of caving to industry, just days after former advisor Calley Means did the same. (Politico)
HHS Secretary Robert F. Kennedy Jr., who was thought only...
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5,387 Dead in Outbreak; Cheese Recall Expands; Breast Cancer Chemo May Speed Aging
(MedPage Today) -- Note that some links may require registration or subscription.
According to the latest data, 11,042 confirmed cases have been recorded in Congo's record-breaking Ebola outbreak, including 5,387 deaths. (AP)
Ahead of a formal...
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Two Biologics for Psoriatic Arthritis Square Off in Big Trial
(MedPage Today) -- ORLANDO--A large head-to-head trial reported here that pitted bimekizumab (Bimzelx) against risankizumab (Skyrizi) as treatment for psoriatic arthritis (PsA) yielded a winner, albeit with a couple caveats.
Arthritic symptoms...
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Rheumatoid Arthritis Does Not Improve the Menopause Experience
(MedPage Today) -- ORLANDO--Women with rheumatoid arthritis (RA) had a worse menopause experience compared with the non-RA individuals going through the transition, a researcher reported here.
Symptom severity, as evaluated with the Menopause...
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HHS Vaccine Task Force Misses Report Deadline
(MedPage Today) -- Now that the deadline has passed for an HHS vaccine task force to issue its report on the timing and sequencing of vaccines, public health advocates are concerned about what happens when the report eventually comes out.
"The...
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Novel siRNA Therapeutic Cuts Liver Fat in MASLD, Early Trial Shows
(MedPage Today) -- One dose of a novel small interfering RNA (siRNA) therapy--CIDEBsiRNA (also known as ALN-CIDEB)--led to normal liver fat content and lower alanine aminotransferase (ALT) levels in most patients with metabolic dysfunction...
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Bioengineered Liver System Passes Safety Test in Phase I Trial
(MedPage Today) -- A single-use bioengineered liver paired with an extracorporeal blood circuit that replicates key functions of a human liver was shown to be safe among patients with syndromes of liver failure in a small phase I trial.
There...
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More Women on Testosterone; Hormone Patch Updates; Drug-Induced Bone Loss
(MedPage Today) -- Testosterone use among females has risen since 2016 and is frequently prescribed without a documented diagnosis of hypoactive sexual desire disorder, the sole evidence-based indication. (Journal of Clinical Endocrinology &...
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GLP-1 Pill Shows Benefit in Sleep Apnea
(MedPage Today) -- The oral GLP-1 receptor agonist orforglipron (Foundayo) improved sleep-disordered breathing in patients with moderate-to-severe obstructive sleep apnea and overweight or obesity, two phase III trials showed.
For the treatment...
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Billy Joel Back on Stage; Alzheimer's and Sleep; Predicting Parkinson's Progression
(MedPage Today) -- Musician and songwriter Billy Joel announced his first official show since his normal pressure hydrocephalus diagnosis. (People)
Topline results from a phase II study showed that treatment with investigational PGN-EDODM1 led...
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Another Option for Rare Benign Soft-Tissue Tumor Wins FDA Approval
(MedPage Today) -- The FDA approved the small-molecule inhibitor pimicotinib (Pimjetmi) for selected patients with symptomatic tenosynovial giant cell tumor (TGCT) and high surgical risk.
An oral selective inhibitor of colony stimulating factor...
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ADA Publications Chief Resigns
(MedPage Today) -- The vice president of publications at the American Diabetes Association (ADA) has resigned amid the ongoing boycott of the organization.
Christian Kohler, who was with the ADA for 22 years, expressed "profound disappointment...
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Next-Gen Anticoagulant Lands FDA Nod for Secondary Stroke Prevention
(MedPage Today) -- The FDA approved asundexian (Sunharbo) as the first factor XIa (FXIa) inhibitor for secondary stroke prevention, the agency announced on Monday.
Asundexian, an oral, direct, small-molecule inhibitor of FXIa, is indicated for...
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