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PICU Use for Bronchiolitis Tied to 'Striking' Rise in Noninvasive Breathing Support
via medpagetoday.com(MedPage Today) -- The growing role of pediatric intensive care units (PICUs) for managing bronchiolitis in infants and young toddlers over the last decade was associated with increased use of noninvasive respiratory support, but without a corresponding... -
Late-Window Tenecteplase for Stroke Works When Thrombectomy's Out of the Question
via medpagetoday.com(MedPage Today) -- For stroke patients, late administration of tenecteplase improved clinical outcomes in situations in which thrombectomy was not available immediately, according to the Chinese TRACE-III trial.
Patients with ischemic stroke due... -
SGLT2 Inhibitor No Help for ICU Patients With Acute Organ Dysfunction
via medpagetoday.com(MedPage Today) -- Adding an SGLT2 inhibitor to standard care did not improve clinical outcomes in critically ill patients with acute organ dysfunction, an open-label randomized trial involving intensive care units (ICUs) in Brazil found.
In the... -
Inside the Struggle to Improve Diversity, Equity, and Inclusion in Academic Medicine
via medpagetoday.com(MedPage Today) -- Leaders in diversity, equity, and inclusion (DEI) at academic health centers reported several core challenges in their roles that have led to burnout and isolation, according to a qualitative study.
Key themes that emerged from... -
The Next Big Challenges for Medication Abortion
via medpagetoday.com(MedPage Today) -- In the wake of the Supreme Court's decision to preserve access to mifepristone (Mifeprex) on Thursday, abortion-rights groups worry the threat has not passed while anti-abortion groups agree they're not done fighting against... -
What to Know About Medetomidine and Drug Overdoses
via medpagetoday.com(MedPage Today) -- Medetomidine, an animal tranquilizer more potent than xylazine, recently appeared in drug overdoses in several states in combination with the synthetic opioid fentanyl, sparking concern among public health officials.
Medetomidine... -
Atezolizumab Consolidation Impresses in High-Risk DLBCL
via medpagetoday.com(MedPage Today) -- Postchemotherapy consolidation with atezolizumab (Tecentriq) led to a surprisingly high 2-year disease-free survival (DFS) in high-risk diffuse large B-cell lymphoma (DLBCL), a prospective nonrandomized trial showed.
Patients... -
Some Pasteurization Methods May Not Clear H5N1 in Heavily Infected Milk
via medpagetoday.com(MedPage Today) -- Heating raw milk spiked with H5N1 to temperatures commonly used in commercial pasteurization resulted in a decrease in infectious virus within seconds to minutes, according to a brief study, though some infectious material remained... -
Novel URAT1 Inhibitors Advance for Gout
via medpagetoday.com(MedPage Today) -- VIENNA--Improved drugs to force uric acid excretion as a means of treating gout are inching closer to clinical availability in the U.S., with new data reported for two such products.
For one, a product called dotinurad already... -
Here's What Is Wrong With the National Academies' Long COVID Definition
via medpagetoday.com(MedPage Today) -- The National Academies of Sciences, Engineering, and Medicine has just proposed a new case definition for long COVID. The criteria specify that the condition "is present for at least 3 months as a continuous, relapsing and remitting... -
People Flock to Indian City to Swallow Live Fish as 'Miracle Cure' for Asthma
via medpagetoday.com(MedPage Today) -- HYDERABAD, India--A mother encourages her daughter to fully open her mouth to swallow a live fish holding "the medicine" she believes will help cure her child's asthma, as scores clamor about, gulping down their own fish... -
Kate Middleton Gives Cancer Update
via medpagetoday.com(MedPage Today) -- Kate Middleton, the Princess of Wales said Friday she is "making good progress" in her cancer treatment and will attend Saturday's royal Trooping the Color ceremony, Kate's first public appearance since her diagnosis.
The 42... -
PPI Prevents Upper GI Bleeds During Intubation, With No Effect on Mortality
via medpagetoday.com(MedPage Today) -- The common practice of using proton-pump inhibitors (PPIs) as prophylaxis against stress ulcers during invasive ventilation significantly reduced the risk of problematic gastrointestinal (GI) bleeds, without affecting mortality... -
OA Patients Get Long-Term Benefit From Lifestyle Improvements
via medpagetoday.com(MedPage Today) -- VIENNA--Two years after completing a 4-month program to improve eating and exercise habits in a randomized controlled trial, the benefits in pain and function for patients with osteoarthritis (OA) were maintained for a full... -
Stereotactic Radiotherapy Reduces Use of Anti-VEGF Therapy in Neovascular AMD
via medpagetoday.com(MedPage Today) -- Stereotactic radiotherapy (SRT) for neovascular age-related macular degeneration (nAMD) reduced the use of anti-vascular endothelial growth factor (VEGF) medications without significantly affecting visual acuity, a randomized... -
Adding Isatuximab to Standard Backbone Prolongs PFS in Myeloma
via medpagetoday.com(MedPage Today) -- Combining the anti-CD38 monoclonal antibody isatuximab (Sarclisa) with the standard backbone of bortezomib (Velcade), lenalidomide (Revlimid), and dexamethasone (VRd) significantly improved progression-free survival (PFS) in... -
FDA Took Months to React to Complaint About Abbott's Formula Factory, Audit Finds
via medpagetoday.com(MedPage Today) -- The FDA took more than 15 months to act on a whistleblower complaint it received about conditions at an Abbott Nutrition factory that was at the center of a nationwide shortage of infant formula, a new audit shows.
The Department... -
Doc Paralyzed After COVID; Legionella at Medicare HQ; Mystery Grand Canyon Illness
via medpagetoday.com(MedPage Today) -- Note that some links may require registration or subscription.
William Dugal, MD, a 32-year-old doctor from North Carolina, said he was left totally paralyzed with Guillain-Barre syndrome days after a case of COVID-19; he's... -
Osimertinib Plus SABR Appears Safe, Effective for Advanced EGFR-Mutant NSCLC
via medpagetoday.com(MedPage Today) -- In this exclusive MedPage Today video, Erminia Massarelli, MD, PhD, co-director of the lung cancer and thoracic oncology program at City of Hope in Duarte, California, discusses the results and implications of a phase II study... -
Early Menopause Tied to Higher Risk of Respiratory Mortality
via medpagetoday.com(MedPage Today) -- Early menopause due to bilateral oophorectomy was associated with an increased risk of respiratory mortality, according to a secondary analysis of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening trial.
That... -
CDC Warns of Risks for ADHD Patients After Disruption of Online Adderall Prescriber
via medpagetoday.com(MedPage Today) -- Disrupted access to prescription stimulants for patients with attention deficit-hyperactivity disorder (ADHD) may increase risks of injury or overdose, the CDC warned on Thursday following the indictment of executives of an online... -
CDC: ADHD Patients at Risk of Injury After Online Adderall Prescriber Indicted
via medpagetoday.com(MedPage Today) -- Disrupted access to prescription stimulants for patients with attention deficit-hyperactivity disorder (ADHD) may increase risks of injury or overdose, the CDC warned on Thursday following the indictment of an online ADHD medication... -
Liberal Blood Transfusion After Traumatic Brain Injury May Hold Benefit
via medpagetoday.com(MedPage Today) -- A liberal blood transfusion strategy didn't reduce the risk of an unfavorable neurologic outcome at 6 months in critically ill patients with traumatic brain injury (TBI) but showed other possible benefits, the HEMOTION trial... -
Increase $$ for Physicians, Institute Site-Neutral Payment, MedPAC Report Suggests
via medpagetoday.com(MedPage Today) -- Boosting physician fee-for-service (FFS) payment rates and implementing site-neutral payment are among the ideas discussed in the Medicare Payment Assessment Commission's (MedPAC) June report to Congress, which was released Thursday... -
Mom Allergic to Breastfeeding? Rare but It Happens.
via medpagetoday.com(MedPage Today) -- A woman said she developed hives all over her body after breastfeeding her newborn son. The woman, who shared her story on social media, said she went to the doctor after also developing a headache and was told a surprising answer... -
Symptoms May Remain the Best Clue for Concussion Evaluation
via medpagetoday.com(MedPage Today) -- Reported symptoms were more accurate for concussion diagnosis than objective cognitive testing was, a case-control study of National Collegiate Athletic Association (NCAA) athletes found.
Diagnostic utility--a combined measure... -
Type 1 Diabetes in Older People Has Nearly Tripled Globally Since the '90s
via medpagetoday.com(MedPage Today) -- Global prevalence of older people living with type 1 diabetes mellitus jumped 180% in the past 30 years, a population-based study found.
This represents an increase from 1.3 million people worldwide in 1990 to 3.7 million in... -
APOE Genotypes and Dementia
via medpagetoday.com(MedPage Today) -- Many studies have reported on the relationship between the apolipoprotein E (APOE) gene and Alzheimer's disease, but its role in other dementia-related outcomes isn't clear.
At the 2024 American Geriatrics Society meeting, a... -
Upping Immunotherapy Activity; A Win for Lung Screening; Looming Drug Price Break?
via medpagetoday.com(MedPage Today) -- Finding a way to dissociate the activity of effector T cells from regulatory T cells could make immune checkpoint inhibitors more effective in the 60% of melanoma patients who do not benefit or develop resistance to the drugs... -
AI System Beats Radiologists in Detecting Clinically Significant Prostate Cancer
via medpagetoday.com(MedPage Today) -- An artificial intelligence (AI) system was better at detecting clinically significant prostate cancer on MRI compared with radiologists, a noninferiority, confirmatory study showed.
In a subset of 400 testing cases in which...
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