(MedPage Today) -- The FDA on Tuesday approved bepirovirsen (Hibsago) as a potential functional cure for adults with chronic hepatitis B, but with no cirrhosis, who are taking antiviral therapy.
Approval was based on findings from the B-Well 1...
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FDA Green Lights Potential Functional Cure for Chronic Hep B
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Tirzepatide Cuts BMI in Adolescents With Obesity in Phase III Trial
(MedPage Today) -- NATIONAL HARBOR, Md.--Tirzepatide (Zepbound) yielded substantial reductions in BMI among adolescents with obesity or overweight with obesity-related complications, the phase III SURMOUNT-ADOLESCENTS trial showed.
At week...
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'Opioids Cause Pain. Full Stop.': What We Heard This Week
(MedPage Today) -- "Opioids cause pain. Full stop."--Jeffrey Glassberg, MD, of the Icahn School of Medicine at Mount Sinai in New York City, commenting on the use of opioids to treat sickle cell disease pain.
"This is not a frivolous exercise...
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Omalizumab Linked With Anaphylaxis Elimination in Meat Allergy
(MedPage Today) -- For patients with alpha-gal syndrome who had severe allergic reactions to red meat despite avoidance, treatment with omalizumab (Xolair) appeared to eliminate anaphylaxis risk in one case series.
Whereas 53% of 64 such patients...
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The Fine Print on Our National Bet
(MedPage Today) -- Nothing is more absurd than a direct-to-consumer pharmaceutical commercial, or an online sports betting commercial.
At least the pharmaceutical ad has the decency to be honest about its absurdity. A smiling couple strolls along...
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U.S. Flu season Is Off to a Very Early Start. It's Targeting the South and West Now
(MedPage Today) -- The U.S. flu season is off to a very early start, and it's quickly intensifying.
The CDC on Friday posted its latest update, reporting that seven states were reporting high flu activity last week, up from two states the week...
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Could Early Eosinophilic Esophagitis Treatment Prevent Asthma?
(MedPage Today) -- Early treatment with dupilumab (Dupixent) for eosinophilic esophagitis in young children was associated with reduced risk of developing asthma, an observational study showed.
Among children in a large commercial insurance database...
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Israeli Strike on Hospital Highlights the Devastation to Gaza's Healthcare System
(MedPage Today) -- BEIRUT--A deadly airstrike on the biggest hospital in the southern Gaza Strip highlighted the devastation that Israel's campaign has wreaked on the Palestinian territory's healthcare system over the past 3 years.
The strike...
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Early-Onset Colorectal Cancer; AI-Enabled Prior Auth; Type 1 Diabetes Subtypes
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of Texas Tech Health El Paso, look at the top medical...
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Trump Admin Pauses Enforcement of Its Medicaid Work Rules
(MedPage Today) -- President Donald Trump's administration told states Friday that they can wait until July before removing people from Medicaid for failing to meet a work requirement.
The requirement is scheduled to take effect nationally on...
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Are AI Data Centers a Health Concern?
(MedPage Today) -- With the public release of ChatGPT in late 2022, artificial intelligence (AI) has been thrust into the mainstream--incorporated into various industries as well as our personal lives. In healthcare, AI scribes are prominent...
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More Measles Deaths Reported as U.S. Cases Top 5,400
(MedPage Today) -- Wisconsin and Pennsylvania reported two more measles-associated deaths on Friday, as the U.S. stands on the brink of losing its measles elimination status with more than 5,400 cases.
Wisconsin health officials reported a measles...
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Injectable Nanobody Wins FDA Approval for Myasthenia Gravis
(MedPage Today) -- The FDA on Friday approved injectable gefurulimab (Klygefa), a dual-binding nanobody that blocks complement component 5 (C5) activation, to treat generalized myasthenia gravis in adults who are anti-acetylcholine receptor (AChR...
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What Was FDA's GLP-1 Warning About?
(MedPage Today) -- You passed medical training, now see if you can pass our weekly quiz
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Shorter Cycle Maintains Efficacy of Colorectal Cancer Regimen
(MedPage Today) -- A shorter cycle length for a standard treatment for refractory metastatic colorectal cancer was noninferior to the typical longer length for overall survival (OS), while limiting toxicity, the phase III PRABITAS trial from Japan...
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Democrat Pitches 'TrumpCare': Universal Healthcare From Cradle to Grave
(MedPage Today) -- Abdul El-Sayed, MD, DPhil, has proposed "TrumpCare," a golden insurance card providing universal healthcare, dangling the president's name on the ambitious Democratic plan.
James Talarico has suggested Donald Trump could become...
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Cervical Cancer Burden Persists; Cancer Trial Payments; Fighting Cancer With Nerves
(MedPage Today) -- Despite increased uptake of vaccination against human papillomavirus, the global burden of cervical cancer appears unlikely to reach the World Health Organization's goal of eradication by 2050. (CIDRAP)
Combat Medical reported...
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Trial on Statins for Cirrhosis Won't End Debate Anytime Soon
(MedPage Today) -- Statin therapy delivered a statistical near miss at lowering risks of hepatic decompensation and liver cancer in patients with compensated cirrhosis, the phase III SACRED trial showed.
In an intention-to-treat analysis, 8.97...
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Alzheimer's Study Tracks Faster Tau Buildup in Younger Patients
(MedPage Today) -- People with early-onset Alzheimer's disease had faster and more severe accumulation of tau than those whose Alzheimer's symptoms started after age 65, imaging data showed.
Compared with older Alzheimer's patients, tau burden...
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U.S. on the Verge of Forfeiting Major Public Health Victory on Measles
(MedPage Today) -- International health experts are meeting this week to determine if the U.S. and Mexico have forfeited one of their greatest public health victories--the elimination of measles.
Measles is one of the most contagious diseases...
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Trump's FDA Pick on Thin Ice; AI to Fight Insurance Denials; Coffee and Gut Health
(MedPage Today) -- Note that some links may require registration or subscription.
Doubts have emerged among Senate Republicans about Heidi Overton, MD, PhD, President Trump's pick to run the FDA, just days before a key vote on her nomination by...
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Major Change to Prostate Cancer Screening Guidelines
(MedPage Today) -- Shifting gears on prostate cancer screening, the American Cancer Society (ACS) now recommends screening with prostate-specific antigen (PSA) every 2 years for average-risk men ages 50 to 69.
Since the release of its previous...
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Prescriptions Down 25%, Overdoses Cut in Half: What Stopped a Gabapentinoid Surge?
(MedPage Today) -- High-profile media coverage of the harms associated with the gabapentinoid pregabalin (Lyrica) and tighter safeguards coincided with fewer prescriptions and overdoses in Australia, a retrospective study showed.
Following a media...
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MD Defends 'The Pitt'; Dr. Glaucomflecken Talks Surprise Billing; Holiday Health PSA
(MedPage Today) -- The following contains links to social media websites including Bluesky, X, TikTok, Instagram, Facebook, and LinkedIn.
"You can't copyright the emergency room." An emergency physician defended the originality of "The Pitt,...
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Trump Officials Will Fund New Research on Controversial Psychedelic Drug Ibogaine
(MedPage Today) -- Federal officials on Thursday announced new funding to explore the medical potential of ibogaine, a controversial psychedelic drug championed by veterans, conservative lawmakers, and podcasters aligned with President Donald Trump...
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Response to Standard PBC Treatment at 1 Year Linked to Lower Long-Term Risks
(MedPage Today) -- A biochemical response to ursodeoxycholic acid (UDCA) at 12 months was associated with lower 5-year risks of hepatic decompensation and mortality in patients with primary biliary cholangitis (PBC), a propensity-matched landmark...
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Advances and Unmet Needs in Pediatric Sickle Cell Disease
(MedPage Today) -- As the 1970s came to a close, sickle cell disease (SCD) remained largely a pediatric condition because few children born in the U.S. with the condition survived to adulthood. Today, about 95% of children born with SCD in developed...
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Another Promising Study on Statins in Compensated Cirrhosis
(MedPage Today) -- Statin initiation among adults with compensated cirrhosis was associated with a lower risk of hepatic decompensation and lower overall mortality, according to a large observational study.
Among over 18,000 patients, the cumulative...
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Managing Metastases in Advanced Prostate Cancer
(MedPage Today) -- In "Beyond Diagnosis: Metastatic Castration-Sensitive Prostate Cancer," Cleveland Clinic oncologist Christopher Wee, MD, and host John Mangels discuss how clinicians can guide patients through the growing complexities of treatment...
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Senators Investigate Whether RFK Jr. Lied to Congress About Samoa Trip
(MedPage Today) -- Two Democratic senators are launching an investigation into whether Health Secretary Robert F. Kennedy Jr. lied to Congress about his reason for a 2019 trip to Samoa after the Associated Press and the Guardian published documents...
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