(MedPage Today) -- An analysis of patent applications for 10 top-selling prescription drugs found that nearly three-quarters of them were filed after FDA approval, a cross-sectional study of U.S. patent thickets found.
The 10 brand-name drugs...
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-
Blockbuster Drug Patent Thickets Signal 'Strategic Behavior'
via medpagetoday.com -
FDA Reviewers Question Patient Selection for Alzheimer's Drug Candidate
via medpagetoday.com(MedPage Today) -- Whether certain groups of early Alzheimer's patients are more likely than others to benefit from investigational donanemab is a key question FDA advisors will try to untangle when they meet on June 10.
In briefing documents... -
Texas Rancher Develops Rare Case of Anthrax After Butchering Dead Lamb
via medpagetoday.com(MedPage Today) -- A rancher in Texas contracted anthrax earlier this year after butchering a lamb that died suddenly on his ranch, CDC researchers said.
Two wound swabs from the rancher, a male in his 50s, were positive for Bacillus anthracis... -
Hyperoxia Improves Some Respiratory Outcomes Post-Anesthesia in Small Study
via medpagetoday.com(MedPage Today) -- HOUSTON--A liberal oxygen intervention to induce hyperoxia improved respiratory disturbances in post-operative patients during recovery from anesthesia, results from a small single-blind trial revealed.
In the 10-patient... -
Can Mitral Valve Innovators Dig Themselves Out of a Rut?
via medpagetoday.com(MedPage Today) -- NEW YORK CITY--Mitral valve technology developers were urged to go back to the drawing board due to current-generation devices not meeting the needs of enough patients with mitral regurgitation (MR), some said.
With lots... -
North Carolina Lawmakers Add Health Exemption to Bill Limiting Masking
via medpagetoday.com(MedPage Today) -- Republican lawmakers in North Carolina struck a compromise on a bill that now maintains a health exemption for masking in public while preventing the use of masks during criminal activity, but only one chamber chose to vote on... -
Near-Perfect Control of Slow-Growing Lymphoma With Low-Dose Radiotherapy
via medpagetoday.com(MedPage Today) -- Low-dose radiotherapy for a slow-growing stomach lymphoma achieved near-perfect disease control with no severe toxicity, a small prospective study showed.
After a 4 Gy dose of radiotherapy in two fractions, 20 of 24 patients... -
Juul Vaping Products' Stay of Execution Is Now More Official
via medpagetoday.com(MedPage Today) -- In yet another delay in FDA action to regulate electronic cigarettes, the agency announced it was rescinding its earlier denial of the marketing orders necessary for Juul to keep its vaping products on retail shelves.
The FDA... -
Guess Which Specialty Gets the Most Behavior Complaints From Coworkers ...
via medpagetoday.com(MedPage Today) -- Complaints of unprofessional behavior about a physician coworker were not uncommon in a 5-year retrospective cohort study, with surgeons most likely to be on the receiving end of those complaints.
Among more than 35,000 physicians... -
Increased Heart Risks With Newer Prostate Cancer Drugs, Meta-Analysis Shows
via medpagetoday.com(MedPage Today) -- The addition of androgen receptor signaling inhibitors (ARSIs) alongside standard androgen deprivation therapy (ADT) in advanced prostate cancer was associated with a significantly increased risk of adverse heart events, a systematic... -
Humira Clobbers Biosimilars in Battle for Part D Coverage
via medpagetoday.com(MedPage Today) -- Just about every Medicare Part D prescription drug plan on offer this year covers the original version of adalimumab (Humira), whereas only about half will pay for any of the several biosimilar versions currently approved, researchers... -
'Unusual' Cancers After Pandemic; A Win in TNBC; Shortage Pauses Clinical Trial
via medpagetoday.com(MedPage Today) -- Some "unusual" cancers emerged during the pandemic, but is COVID to blame? (Washington Post)
Using routinely collected information about patients with cancer, an artificial intelligence model showed promise for predicting which... -
Bulevirtide/Pegylated Interferon Combo Beats Monotherapy for Chronic Hepatitis D
via medpagetoday.com(MedPage Today) -- Treatment with the investigational drug bulevirtide plus pegylated interferon alfa-2a (PegIFNα) resulted in more patients achieving undetectable levels of hepatitis D virus (HDV) RNA compared with bulevirtide alone, according... -
Intoxicated Without Drinking? 60-Second Diagnosis; Gastro Docs Talk Gut Health
via medpagetoday.com(MedPage Today) -- The following contains links to social media websites including X, TikTok, Instagram, Facebook, and LinkedIn.
Can you imagine being drunk for 2 years and not knowing why? Emergency physician @doctor.darien shared on TikTok a... -
Study Shows No Link Between Paternal Valproate Use and Neurodevelopmental Disorders
via medpagetoday.com(MedPage Today) -- Paternal use of the anti-seizure medication valproate during spermatogenesis was not associated with a risk of congenital malformations or neurodevelopmental disorders in offspring, an observational cohort study from Denmark... -
Man Sentenced in Physician Wife's Murder; Research Beagle Company Fined Heavily
via medpagetoday.com(MedPage Today) -- A Las Vegas man who stabbed his physician wife to death for going out to celebrate the end of her first year of residency was sentenced to between 10 and 25 years in prison. (People)
A research beagle breeder pleaded guilty... -
Republican Senators Block Bill to Federally Protect Contraception Access
via medpagetoday.com(MedPage Today) -- Senate Republicans have blocked legislation designed to protect women's access to contraception, arguing that the bill was just a political stunt as Democrats mount an election-year effort to put GOP senators on the record on... -
Food Addiction Should Be Included in the DSM-6
via medpagetoday.com(MedPage Today) -- In the evolving landscape of mental health diagnostics, the Diagnostic and Statistical Manual of Mental Disorders (DSM) stands as the cornerstone. While it is far from a perfect tool, its revisions shape clinical practice and... -
World-First Trial Shows Benefits of Finding, Treating Undiagnosed Asthma, COPD
via medpagetoday.com(MedPage Today) -- Identifying symptomatic individuals in the community with undiagnosed asthma and chronic obstructive pulmonary disease (COPD), and then linking them with pulmonologist care, reduced healthcare utilization and symptom burden... -
Cucumbers Hospitalize 54; First H5N2 Bird Flu Death; FDA Warns on Oysters, Clams
via medpagetoday.com(MedPage Today) -- Note that some links may require registration or subscription.
The CDC warned of a Salmonella outbreak linked to cucumbers that's so far sickened 162 people and hospitalized 54.
A person in Mexico had the first known case and... -
Phrenic Nerve Stimulation Shows Benefits in Central Sleep Apnea With Heart Failure
via medpagetoday.com(MedPage Today) -- HOUSTON--Use of transvenous phrenic nerve stimulation (TPNS) was linked to a five-fold higher chance of better clinical outcomes for patients with central sleep apnea and heart failure, according to a win ratio analysis of... -
Better Cognitive Outcomes Tied to Vigorous Exercise in Hypertensive Adults
via medpagetoday.com(MedPage Today) -- Vigorous exercise appeared to preserve cognitive function in older adults with hypertension, a post hoc analysis of SPRINT MIND trial data showed.
At least one vigorous physical activity session per week reduced the risk of... -
FDA Advisors Give a Hearty Thumbs Up to a COVID Vaccine Based on the JN.1 Strain
via medpagetoday.com(MedPage Today) -- An FDA advisory committee voted unanimously, 16-0, Wednesday to recommend that the COVID-19 vaccines for the 2024-2025 season target the JN.1 strain of the virus.
"From my review of the data, it appeared that the newer variants... -
FDA Warns Company Making Stem Cell Products for Pets
via medpagetoday.com(MedPage Today) -- FDA has sent a warning letter to a company that makes stem cell and platelet-rich plasma products--for pets.
The agency told Texas-based Safari Stem Cell that statements on the company's website and social media accounts... -
ENDO 2024 Roundup: Teen GLP-1 Coverage; Novel CAH Drug; Hot Flash Risks
via medpagetoday.com(MedPage Today) -- BOSTON--Some of the latest research advancements in hormonal health presented at the Endocrine Society's ENDO 2024 included a daily male birth control gel, semaglutide's taste sensitivity-boosting properties, and a novel... -
Brain-Protected TAVR Results in Fewer Real-World Disabling Strokes
via medpagetoday.com(MedPage Today) -- NEW YORK CITY--Researchers eked out evidence of a small clinical benefit with the Sentinel cerebral embolic protection (CEP) device in transcatheter aortic valve replacement (TAVR)--and pointed to the patients more likely... -
'Transformative': Novel Drug for Narcolepsy Effective in Mid-Stage Trial
via medpagetoday.com(MedPage Today) -- HOUSTON--An investigational oral drug targeting the lack of brain orexin neuropeptides that characterizes narcolepsy type 1 demonstrated safety and effectiveness for the condition in a phase IIb trial.
At all four doses... -
Surgeons, Trainees Experience Distress After Medical Errors
via medpagetoday.com(MedPage Today) -- Surgeons and surgical trainees almost universally experienced significant distress after adverse patient events, but female trainees and those with a minority racial or ethnic background disproportionately experienced negative... -
More Salty Diets Linked to Higher Risk of Atopic Dermatitis
via medpagetoday.com(MedPage Today) -- A higher level of daily sodium intake was associated with an increased risk of atopic dermatitis, a cross-sectional study suggested.
In a cohort of over 215,000 adults from the U.K. Biobank, multivariable logistic regression... -
Mental Health Dominates Telehealth; Top Psychiatrist Sued; College PTSD Doubles
via medpagetoday.com(MedPage Today) -- In 2021, 43.2% of visits to psychiatrists occurred by telehealth versus 4.5% of visits to other physicians. (Annals of Internal Medicine)
One in three U.S. adults knew someone who died of a drug overdose, cross-sectional data...
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