(MedPage Today) -- Researchers analyzing previous trials of hyaluronic acid injections for knee osteoarthritis (OA) found that, although measurable benefit was demonstrated, it was too small to be clinically relevant.
Pooled data from 24 large...
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-
Lubricant Shots for Knee OA: No, They Really Don't Help
via medpagetoday.com -
CEND-1 Offers Hope in Advanced Pancreatic Cancer
via medpagetoday.com(MedPage Today) -- Chemotherapy combined with the CEND-1 cyclic peptide showed promising efficacy, and was well tolerated as a first-line treatment, for patients with metastatic pancreatic cancer, researchers reported.
In a phase I study of 29... -
Bust for Balovaptan in Treatment of Childhood Autism
via medpagetoday.com(MedPage Today) -- An oral selective vasopressin 1a (V1a) receptor antagonist failed at improving socialization and communication among those with pediatric autism spectrum disorder (ASD) in a randomized, double-blind study.
When compared with... -
FDA Getting Tougher on Birth Tissue Companies
via medpagetoday.com(MedPage Today) -- The FDA may be getting tougher on birth tissue injection companies, experts in stem cells and regenerative medicine said.
In its most recent warning letter to one such company, Re-Gen Active Lab, FDA stated outright that use... -
Memoirs of a 'Recovering' Peer Reviewer
via medpagetoday.com(MedPage Today) -- In theory, the application of evidenced-based guidelines assists in reducing unwarranted variation in clinical practice and improving the quality and cost of care. Guideline developers, health plans, and their benefit managers... -
Fewer Complications With Robotic Nephrectomy in Complex Kidney Tumors
via medpagetoday.com(MedPage Today) -- Robotic-assisted partial nephrectomy (RAPN) led to a lower rate of complications compared with open partial nephrectomy (OPN) in patients with intermediate- or high-complexity kidney tumors, the randomized OpeRa trial found... -
Hypothyroidism May Predict Dementia in Golden Years
via medpagetoday.com(MedPage Today) -- Older people with a history of hypothyroidism may be at a much higher risk for developing dementia, a Taiwanese study found.
Among patients ages 65 and older, hypothyroidism was linked with an 81% increased risk of being diagnosed... -
Anti-LAG-3, Pembrolizumab Doublet Continues to Impress in Metastatic NSCLC
via medpagetoday.com(MedPage Today) -- At the recent American Society of Clinical Oncology (ASCO) annual meeting, updated results of a phase II trial showed that the lymphocyte activation gene (LAG)-3 inhibitor eftilagimod alpha in combination with pembrolizumab ... -
People With Gum Disease Are More Prone to Heart Failure
via medpagetoday.com(MedPage Today) -- The link between periodontal disease and heart failure (HF) was reinforced by long-term data from the Atherosclerosis Risk in Communities (ARIC) cohort.
Among study participants with full-mouth periodontal exams in 1996-1998... -
ASCO 2032: What Will Be the Big Story in Lung Cancer?
via medpagetoday.com(MedPage Today) -- New clinical research unveiled at the recent American Society of Clinical Oncology (ASCO) annual meeting has the potential to significantly alter the treatment of lung cancer. But what will be the innovations we are talking about... -
FDA Gives Pharmacists Thumbs Up for Paxlovid Prescribing
via medpagetoday.com(MedPage Today) -- Licensed pharmacists can now prescribe nirmatrelvir-ritonavir (Paxlovid) for COVID-19 patients at high risk of progressing to severe disease (though with some limitations), the FDA announced on Wednesday.
"Since Paxlovid must... -
Promising New Depression Tx; Racially Skewed ADHD Dx; Effective Clozapine Monitoring
via medpagetoday.com(MedPage Today) -- The FDA gave ANeuroTech positive feedback during a pre-investigational new drug meeting on the phase IIIb clinical program testing their drug ANT-01 as adjunctive therapy for major depression, the company announced.
Is there... -
T1D Stem Cell Trial Back On; Fifth Grade Obesity; Islet Autoantibodies Predictive
via medpagetoday.com(MedPage Today) -- After being hit with a clinical hold, Vertex Pharmaceuticals announced it's been given the FDA green-light to push forward on its phase I/II trial for the investigative type 1 diabetes stem cell treatment VX-880.
According to... -
Here's How Many U.S. Deaths COVID Vaccines Prevented
via medpagetoday.com(MedPage Today) -- The U.S. COVID-19 vaccination program prevented millions of infections as well as hundreds of thousands of deaths, according to a modeling study.
From December 2020 through September 2021, COVID-19 vaccines were estimated to... -
Prenatal Exposure to Everyday Chemicals Tied to Liver Injury in Kids
via medpagetoday.com(MedPage Today) -- Prenatal environmental exposure to endocrine-disrupting chemicals was associated with a higher risk for liver injury in children, a prospective cohort study found.
In the study of over 1,000 European mother-child pairs, the... -
FLCCC Co-Founder's Medical License Expires
via medpagetoday.com(MedPage Today) -- Paul Marik, MD, one of the founding members of the Front Line COVID-19 Critical Care Alliance (FLCCC), which has touted ivermectin as a treatment for COVID-19, has let his medical license expire.
The critical care physician... -
Doc Who Pushed HCQ Dies; Fauci's Final Pandemic; Will Abortion Bans Restrict IVF?
via medpagetoday.com(MedPage Today) -- Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week.
Doctor Who Pushed HCQ as Early COVID Treatment Dies
Vladimir Zelenko, MD, an upstate New... -
Hey Siri: Is Health Info From Voice Assistants Accurate?
via medpagetoday.com(MedPage Today) -- All voice assistants are not created equal, at least not when it comes to providing their users with helpful and correct medical information.
Cases of colorectal cancer have been steadily rising in younger adults, including... -
Which Biologics Stick Longest for Psoriasis?
via medpagetoday.com(MedPage Today) -- Patients stayed longer with guselkumab (Tremfya) for psoriasis treatment than any other biologic drug, while adalimumab (Humira) was dropped the quickest, British registry data indicated.
With ustekinumab (Stelara) chosen arbitrarily... -
Every Day, I Live My Life in Pain
via medpagetoday.com(MedPage Today) -- In 1982, at the age of 31, I was diagnosed with a small-fiber length-dependent sensory peripheral neuropathy. Despite extensive laboratory assessments (including genome sequencing), the cause is unknown. Most patients with small... -
Case of the Stolen Body Parts; Monkeypox Surges; What Do Long COVID Numbers Mean?
via medpagetoday.com(MedPage Today) -- Note that some links may require registration or subscription.
A Colorado woman pleaded guilty to mail fraud that involved stealing and selling body parts for scientific, medical, or educational purposes, according to the Department... -
The Doctor as Detective
via medpagetoday.com(MedPage Today) -- "The Doctor's Art" is a weekly podcast that explores what makes medicine meaningful, featuring profiles and stories from clinicians, patients, educators, leaders, and others working in healthcare. Listen and subscribe on Apple... -
U.S. Maternal Deaths Spiked Upwards During Pandemic
via medicinenet.comTitle: U.S. Maternal Deaths Spiked Upwards During Pandemic
Category: Health News
Created: 7/4/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Serious Illnesses From Daily Harvest Lentil Crumbles, FDA Investigates
via medicinenet.comTitle: Serious Illnesses From Daily Harvest Lentil Crumbles, FDA Investigates
Category: Health News
Created: 7/1/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Scientists Track the Microbiomes of Stray & Pet Dogs Around the World
via medicinenet.comTitle: Scientists Track the Microbiomes of Stray & Pet Dogs Around the World
Category: Health News
Created: 7/5/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Research Spots Gene That Raises Alzheimer's Risk for Women
via medicinenet.comTitle: Research Spots Gene That Raises Alzheimer's Risk for Women
Category: Health News
Created: 7/4/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Recent Monkeypox Symptoms Differ From Those of Prior Outbreaks
via medicinenet.comTitle: Recent Monkeypox Symptoms Differ From Those of Prior Outbreaks
Category: Health News
Created: 7/4/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Pollutants in Soil Can Harm Your Heart
via medicinenet.comTitle: Pollutants in Soil Can Harm Your Heart
Category: Health News
Created: 7/4/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Poll Finds Many Diabetes Caregivers Exhausted, Lacking Support
via medicinenet.comTitle: Poll Finds Many Diabetes Caregivers Exhausted, Lacking Support
Category: Health News
Created: 7/5/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Only 7% of American Adults in Good Cardiometabolic Health
via medicinenet.comTitle: Only 7% of American Adults in Good Cardiometabolic Health
Category: Health News
Created: 7/5/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
NYC First to Offer Paxlovid at COVID Testing Sites
via medicinenet.comTitle: NYC First to Offer Paxlovid at COVID Testing Sites
Category: Health News
Created: 7/1/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Nerve-Cooling Implant Could Ease Pain Without Opioids
via medicinenet.comTitle: Nerve-Cooling Implant Could Ease Pain Without Opioids
Category: Health News
Created: 7/1/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Most U.S. Kids Score Low on Heart Health
via medicinenet.comTitle: Most U.S. Kids Score Low on Heart Health
Category: Health News
Created: 7/5/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Gas Used in Homes Has Links to Cancer; Leaks Often Undetected
via medicinenet.comTitle: Gas Used in Homes Has Links to Cancer; Leaks Often Undetected
Category: Health News
Created: 7/1/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Deadly Listeria Outbreak Linked to Ice Cream
via medicinenet.comTitle: Deadly Listeria Outbreak Linked to Ice Cream
Category: Health News
Created: 7/5/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
Biggest Weight Gain Now Comes Early in Adulthood
via medicinenet.comTitle: Biggest Weight Gain Now Comes Early in Adulthood
Category: Health News
Created: 7/5/2022 12:00:00 AM
Last Editorial Review: 7/5/2022 12:00:00 AM -
First-Time Cesarean Deliveries Increased in Recent Years
via medpagetoday.com(MedPage Today) -- Cesarean deliveries have increased in the U.S. over the last few years, driven by a rise in patients who underwent first-time C-sections, according to a CDC report.
While the rate of primary C-sections fluctuated from 2016 to... -
What a Lifetime of Gaslighting by Other Doctors Feels Like
via medpagetoday.com(MedPage Today) -- "If your shoulder were really injured, that maneuver would make you scream in pain," he told me confidently.
My husband and I recently established care with a new family doctor. I was frightened and scarred from a long history... -
ADHD Drugs May Treat Alzheimer's Cognitive Symptoms Effectively
via medpagetoday.com(MedPage Today) -- Drugs with principally noradrenergic action--including ones prescribed for attention deficit-hyperactivity disorder (ADHD) or to treat hypertension or depression--may effectively treat cognitive symptoms and apathy in... -
Tentative Reassurance for Weekend Warrior Exercisers
via medpagetoday.com(MedPage Today) -- Researchers fell short of proving that so-called weekend warriors had better survival than inactive peers in a large cohort study, but maintained that this pattern of physical activity has benefit.
Over approximately 10 years... -
Methenamine Hippurate Could Be Alternative Treatment for Recurrent UTI
via medpagetoday.com(MedPage Today) -- The urinary antiseptic methenamine hippurate (Hiprex) was non-inferior to antibiotic prophylaxis in women with a history of recurrent urinary tract infections (UTI), according to results from the ALTAR trial.
Over the course... -
Wide-Ranging Inconsistencies Seen in Estimated, Measured GFR
via medpagetoday.com(MedPage Today) -- There may be a substantial variation between estimated glomerular filtration rate (eGFR) and measured glomerular filtration rate (mGFR) on an individual level, a cross-sectional study suggested.
While there were only small population... -
Unclogging the Specialist Access Pipeline
via medpagetoday.com(MedPage Today) -- As we seek to improve access for our patients, for all the care they need across the spectrum of healthcare, we need to unclog the pipeline in multiple different places.
Just the other day, one of my partners at work walked... -
Advances in the Prevention of GVHD
via medpagetoday.com(MedPage Today) -- Graft-versus-host disease (GVHD) remains one of the most common complications of allogeneic stem cell transplantation (ASCT). Unless the patient's donor is an identical twin, a patient undergoing ASCT will receive some type of... -
Trial: Rinvoq Effective for Biologic-Refractory Ankylosing Spondylitis
via medpagetoday.com(MedPage Today) -- The JAK inhibitor upadacitinib (Rinvoq) outperformed placebo in ankylosing spondylitis patients whose disease hadn't responded to standard biologic drug therapy, phase III trial data showed.
Almost half of patients receiving... -
Can Aging MS Patients Stop Taking Disease-Modifying Therapies?
via medpagetoday.com(MedPage Today) -- A randomized trial presented at the recent Consortium of Multiple Sclerosis Centers (CMSC) annual meeting evaluated the effects of discontinuing disease-modifying therapy for patients with multiple sclerosis (MS) as they age... -
Antibiotics Safe for Some Outpatients With Acute Appendicitis
via medpagetoday.com(MedPage Today) -- Select patients with acute appendicitis who were discharged from the hospital within 24 hours were safely managed with antibiotics as outpatients, a secondary analysis of the CODA Collaborative trial found.
Among over 700 patients... -
Jaundice, Malaise in Woman With Heroin Habit, Inactive Hepatitis B
via medpagetoday.com(MedPage Today) -- HDV diagnosis portends imminent cirrhosis despite initial resolution of symptoms -
Xenotransplant Trials Coming; Avocado Diet a Dud; EMS Defers CPR to Bystander
via medpagetoday.com(MedPage Today) -- The FDA is reportedly paving the way for clinical trials of xenotransplantation. (Wall Street Journal)
One large avocado a day for 6 months did not reduce excess visceral adiposity or other cardiometabolic measures in the HAT... -
Forced Retirement Spotlighted as Risk Factors for Physician Suicide
via medpagetoday.com(MedPage Today) -- Systemic support systems need to be implemented for physicians to prevent work-related stressors that could lead to suicide, a thematic analysis of 200 physician deaths suggested.
Among physician suicides included in the National...
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