Pharmaceutical Industry news

• One-Quarter of Adults in the U.S. Experience Burdensome Health Costs

  23-12-2025 19:41 via drugs.com
  TUESDAY, Dec. 23, 2025-- Overall, 17.4 percent of adults experienced cost burdens and 9.9 percent experienced catastrophic cost burdens (CCBs) over a four-year period, according to a study published online Dec. 22 in JAMA Internal Medicine.Adam...
  
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• FDA Approves Subcutaneous Rybrevant Faspro for EGFR-Mutated Non-Small Cell Lung Cancer

  23-12-2025 19:35 via drugs.com
  TUESDAY, Dec. 23, 2025-- The U.S. Food and Drug Administration has approved Rybrevant Faspro (amivantamab and hyaluronidase-lpuj) as the first and only subcutaneously administered therapy for patients with epidermal growth factor receptor...
  
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• Frequency of Teen Cannabis Use Linked to Psychosocial Indicators

  23-12-2025 16:49 via drugs.com
  TUESDAY, Dec. 23, 2025-- Frequency of cannabis use is associated with adverse academic and impulsivity self-regulation indicators in a dose-dependent manner among adolescents, according to a study published online Dec. 23 in Pediatrics.Ryan S...
  
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• Depression, MACE Link Mediated by Stress-Related Neural Activity

  23-12-2025 16:47 via drugs.com
  TUESDAY, Dec. 23, 2025-- The association between depression and anxiety and major adverse cardiac events (MACE) is partly mediated by increased stress-related neural activity, according to a study published online Dec. 17 in Circulation...
  
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• Major Complications Seen in 7 Percent With ADPKD Undergoing Nephrectomy

  23-12-2025 16:45 via drugs.com
  TUESDAY, Dec. 23, 2025– Major complications occur in 7.0 percent of patients undergoing nephrectomy with a diagnosis of autosomal dominant polycystic kidney disease (ADPKD), according to a study published online Dec. 17 in Urology Practice.Michael...
  
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• Patient Education Can Reduce Preference for Antibiotics for Asymptomatic Bacteriuria

  23-12-2025 16:43 via drugs.com
  TUESDAY, Dec. 23, 2025-- Receipt of a patient-centered educational leaflet decreases the desire to take antibiotics for asymptomatic bacteriuria (ASB), according to a study published in the December issue of Open Forum Infectious Diseases.Alistair...
  
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• Measurement Properties of Kidney Disease Symptom Score Explored in Non-Dialysis-Dependent CKD

  23-12-2025 16:41 via drugs.com
  TUESDAY, Dec. 23, 2025-- The Kidney Disease Symptom Score (KDSS) has temporal stability for patients with non-dialysis-dependent chronic kidney disease (NDD-CKD) with stable kidney function, but responsiveness of the KDSS for physical symptoms and...
  
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• Lipoic Acid Does Not Slow Decline in Walking Speed in Progressive MS

  23-12-2025 16:40 via drugs.com
  TUESDAY, Dec. 23, 2025-- For patients with progressive multiple sclerosis (MS), the antioxidant lipoic acid (LA) does not slow the decline in walking speed or have other clinical effects compared with placebo, according to a study published online...
  
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• HIV Viral Load Test With Next-Day Results Does Not Impact Linkage to Care

  23-12-2025 16:40 via drugs.com
  TUESDAY, Dec. 23, 2025-- For adults at risk for HIV acquisition or people with HIV (PWH) not taking daily antiretroviral therapy (ART), an HIV viral load (VL) test with next-day results does not significantly impact linkage to care, according to a...
  
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• Nerve Block May Reduce Opioid Use After Pediatric Primary Cleft Palate Repair

  23-12-2025 15:11 via drugs.com
  TUESDAY, Dec. 23, 2025-- For pediatric patients undergoing primary cleft palate repair, preoperative ultrasound-guided suprazygomatic maxillary nerve block (SMNB) is associated with a reduction in perioperative morphine consumption, according to a...
  
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• Iron Deficiency Without Anemia Common With Moderate-to-Severe Atopic Dermatitis

  22-12-2025 22:37 via drugs.com
  MONDAY, Dec. 22, 2025-- Iron deficiency without anemia is a common feature of moderate-to-severe atopic dermatitis (AD), according to a study published online Nov. 27 in Nutrients.Małgorzata Ponikowska, from Wroclaw Medical University in Poland...
  
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• Nemolizumab Rapidly Relieves Itch, Sleep Disturbance in Atopic Dermatitis

  22-12-2025 21:28 via drugs.com
  MONDAY, Dec. 22, 2025-- Nemolizumab rapidly relieves itch and sleep disturbance among patients with moderate-to-severe atopic dermatitis (AD) and prurigo nodularis (PN), according to a study published online Dec. 16 in the Journal of the European...
  
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• Six Particular Midlife Depressive Symptoms Predict Dementia Risk

  22-12-2025 17:12 via drugs.com
  MONDAY, Dec. 22, 2025 -- A distinct set of midlife depressive symptoms is associated with an increased risk for dementia, according to a study published online Dec. 15 in The Lancet Psychiatry.
  Philipp Frank, Ph.D., from University College London...
  
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• Recommendations Developed for Managing Adults With Congenital Heart Disease

  22-12-2025 17:12 via drugs.com
  MONDAY, Dec. 22, 2025 -- In clinical practice guidelines issued by the American College of Cardiology and American Heart Association and published online Dec. 18 in both the Journal of the American College of Cardiology and Circulation...
  
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• High Rain From Hurricane Tied to Higher One-Year Mortality in Older Adults

  22-12-2025 17:12 via drugs.com
  MONDAY, Dec. 22, 2025 -- Exposure to high rain from a hurricane is associated with higher one-year mortality that varies across vulnerable groups of older adults, according to a study published online Dec. 16 in the Journal of the American...
  
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• Guidelines Provided for Managing Cancer During Pregnancy

  22-12-2025 17:12 via drugs.com
  MONDAY, Dec. 22, 2025 -- In guidelines issued by the American Society of Clinical Oncology and published online Dec. 11 in the Journal of Clinical Oncology, recommendations are presented for the management of cancer during pregnancy.
  Alison W...
  
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• EACVI: Myocardial Injury Risk Increased After AMI With Elevated Epicardial Adipose Tissue Volume

  22-12-2025 17:12 via drugs.com
  MONDAY, Dec. 22, 2025 -- Patients with elevated epicardial adipose tissue volume (EATV) exhibit greater acute myocardial injury following acute myocardial infarction (AMI), according to a study presented at the annual congress of the European...
  
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• Prediabetes Remission Tied to Long-Term Cardiovascular Benefits

  22-12-2025 16:12 via drugs.com
  MONDAY, Dec. 22, 2025 -- Reaching prediabetes remission is linked to a decades-long benefit, according to a study published online Dec. 12 in The Lancet Diabetes & Endocrinology.
  Elsa Vazquez Arreola, Ph.D., from the National Institute of...
  
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• Gardening, Yardwork Tied to Better Knee Health

  22-12-2025 16:12 via drugs.com
  MONDAY, Dec. 22, 2025 -- Participating in gardening or yardwork may be tied to better knee health, according to a study published online Nov. 21 in Clinical Rheumatology.
  Grace H. Lo, M.D., from Baylor College of Medicine in Houston, and colleagues...
  
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• FDA Approves Exdensur for Severe Asthma

  22-12-2025 16:12 via drugs.com
  MONDAY, Dec. 22, 2025 -- The U.S. Food and Drug Administration has approved Exdensur (depemokimab-ulaa) as an add-on maintenance treatment for severe asthma with an eosinophilic phenotype in adult and pediatric patients aged 12 years and...
  
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• Consensus Statement Declares All Forms of Nicotine Are Cardiovascular Toxins

  19-12-2025 23:15 via drugs.com
  FRIDAY, Dec. 19, 2025-- Nicotine is toxic to the heart and blood vessels, regardless of how it is consumed, according to a consensus statement published Dec. 18 in the European Heart Journal.Thomas Münzel, from Johannes Gutenberg University in...
  
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• Higher Intake of High-Fat Cheese, Cream Inversely Linked to Dementia Risk

  19-12-2025 17:58 via drugs.com
  FRIDAY, Dec. 19, 2025-- Higher intake of high-fat cheese and high-fat cream is associated with a lower risk for all-cause dementia, according to a study published online Dec. 17 in Neurology.Yufeng Du, from Lanzhou University in China, and...
  
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• Women Have Worse Functional Outcomes Than Men After Ischemic Stroke

  19-12-2025 17:53 via drugs.com
  FRIDAY, Dec. 19, 2025-- For ischemic stroke survivors, functional outcomes are worse for women than men up to 12 months after stroke, according to a study published online Dec. 17 in Neurology.Chen Chen, Ph.D., from the University of Michigan...
  
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• High-Dose Rifampin Not Beneficial for Tuberculosis Meningitis

  19-12-2025 17:51 via drugs.com
  FRIDAY, Dec. 19, 2025-- No benefit of high-dose versus standard-dose rifampin is seen among adults with tuberculosis meningitis, according to a study published online Dec. 17 in the New England Journal of Medicine.David B. Meya, M.B., Ch.B...
  
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• Considerable Disparities Identified in Cancer Occurrence, Outcomes

  19-12-2025 17:47 via drugs.com
  FRIDAY, Dec. 19, 2025-- There are considerable disparities in cancer occurrence and outcomes, according to a report published online Dec. 16 in CA: A Cancer Journal for Clinicians.Farhad Islami, M.D., Ph.D., from the American Cancer Society in...
  
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• COVID-19 Vaccination Prior to and During Pregnancy Is Beneficial

  19-12-2025 17:43 via drugs.com
  FRIDAY, Dec. 19, 2025-- During the delta and omicron variant time periods, vaccination against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) prior to and during pregnancy was associated with a lower risk for severe maternal disease...
  
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• Chest Pain, Family History Influence Care-Seeking in Gallstone Disease

  19-12-2025 17:38 via drugs.com
  FRIDAY, Dec. 19, 2025-- Chest pain and family history may influence care-seeking behavior in symptomatic gallstone disease (sGD), according to a study published in the November issue of the Journal of Surgical Research.Noah Z. Freundlich, from...
  
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• 30-Year Smoking Duration-Based Criteria Could Increase Lung Cancer Screening

  19-12-2025 17:35 via drugs.com
  FRIDAY, Dec. 19, 2025-- Thirty-year smoking duration-based criteria could reduce eligibility gaps for all races relative to Whites, while improving six-year lung cancer detection sensitivity, according to a study published online Dec. 16 in the...
  
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• Prolonged Hydrodistention May Provide Longer Symptom Relief in Interstitial Cystitis

  19-12-2025 17:31 via drugs.com
  FRIDAY, Dec. 19, 2025-- For patients with interstitial cystitis (IC), longer cystoscopic hydrodistention (HD) times may result in improved efficacy and longer symptom relief, according to a study published online Nov. 29 in Neurourology and...
  
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• Guideline-Concordant Care Rate ~60 Percent After Positive Lung Cancer Screen in Seniors

  18-12-2025 19:21 via drugs.com
  THURSDAY, Dec. 18, 2025-- Among persons with a first positive lung cancer screening result at age 65 years or older, the rate of guideline-concordant care is 59.7 percent overall, according to a study published online Dec. 16 in the Annals of...
  
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• Pediatric Behavioral Health Expenditures Nearly Doubled From 2011 to 2022

  18-12-2025 19:20 via drugs.com
  THURSDAY, Dec. 18, 2025-- The proportion of pediatric care expenditures for behavioral health increased from 22.4 to 40.2 percent from 2011 to 2022, according to a study published online Dec. 15 in JAMA Pediatrics.Ashley A. Foster, M.D., from the...
  
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• 2012 to 2021 Saw Increase in Cannabinoid Hyperemesis Syndrome

  18-12-2025 19:18 via drugs.com
  THURSDAY, Dec. 18, 2025-- From 2012 to 2021, there was an increase in the prevalence of cannabinoid hyperemesis syndrome (CHS) in Massachusetts, with the highest 10-year prevalence among young adults, Hispanic individuals, Black individuals, and...
  
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• EACVI: Coronary CT Angiography Fractional Flow Reserve Prognostic in Coronary Artery Disease

  18-12-2025 16:44 via drugs.com
  THURSDAY, Dec. 18, 2025-- For patients with coronary artery disease (CAD), coronary computed tomography angiography fractional flow reserve (FFR-CT) is prognostic for adverse outcomes, according to a study presented at the annual congress of the...
  
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• Proportion of Newborns Not Receiving Vitamin K Up From 2017 to 2024

  18-12-2025 16:40 via drugs.com
  THURSDAY, Dec. 18, 2025-- The proportion of newborns not receiving intramuscular vitamin K increased from 2017 to 2024, according to a research letter published online Dec. 8 in the Journal of the American Medical Association.Kristan Scott, M.D...
  
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• Physical Frailty, Depression Linked to Increased Dementia Risk

  18-12-2025 16:40 via drugs.com
  THURSDAY, Dec. 18, 2025-- Individuals with physical frailty and depression have increased risk of dementia, with the highest risk for those with both, according to a study published online Dec. 16 in General Psychiatry.Yihong Ding, from the...
  
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• Zoliflodacin Noninferior for Uncomplicated Urogenital Gonorrhea

  18-12-2025 16:39 via drugs.com
  THURSDAY, Dec. 18, 2025-- Zoliflodacin is noninferior to ceftriaxone plus azithromycin for the treatment of uncomplicated urogenital gonorrhea, according to a study published online Dec. 11 in The Lancet.Alison Luckey, from the Global Antibiotic...
  
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• San Antonio Breast Cancer Symposium, Dec. 9 to 12

  18-12-2025 16:39 via drugs.com
  The annual San Antonio Breast Cancer Symposium was held from Dec. 9 to 12 in San Antonio. Attendees included medical oncologists, radiation oncologists, researchers, and other health care professionals. The conference highlighted recent advances in...
  
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• Smartwatch Cuts Tantrums in Children With Emotional and Behavioral Disorders

  18-12-2025 16:12 via drugs.com
  THURSDAY, Dec. 18, 2025 – A smartwatch system helps parents shorten and defuse children's severe tantrums, according to a study published online Dec. 15 in JAMA Network Open.
  Magdalena Romanowicz, M.D., from the Mayo Clinic in Rochester...
  
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• Reducing, Modifying Saturated Fat Intake Cuts Cardiovascular, Death Risk

  18-12-2025 16:12 via drugs.com
  THURSDAY, Dec. 18, 2025 -- Among persons at high cardiovascular risk, there is low- to moderate-certainty evidence that reducing or modifying saturated fat intake can reduce mortality and major cardiovascular events over five years, according to a...
  
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• Medical Imaging Contrast Media Contribute to Environmental Pollution

  18-12-2025 16:12 via drugs.com
  THURSDAY, Dec. 18, 2025 -- Contrast media from medical imaging may be contributing to environmental pollution, according to a research letter published online Dec. 5 in JAMA Network Open.
  Florence X. Doo, M.D., from the University of Maryland in...
  
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• Higher Frequency or Quantity of Alcohol Intake Tied to Several Cancers

  18-12-2025 16:12 via drugs.com
  THURSDAY, Dec. 18, 2025 -- Alcohol intake, particularly at higher frequency or greater quantity, is associated with elevated risk for multiple cancers, according to a review published online Nov. 13 in Cancer Epidemiology.
  Isabella Abraham, from...
  
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• Efficacy and Safety of Bisphosphonates Explored in Complex Regional Pain Syndrome

  18-12-2025 16:12 via drugs.com
  THURSDAY, Dec. 18, 2025 -- Bisphosphonates may reduce complex regional pain syndrome (CRPS) pain intensity in the short term, according to a study published online Dec. 16 in Annals of Internal Medicine.
  Michael C. Ferraro, from the University of...
  
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• Sports Injuries Sustained During Menstruation Yield Higher Burden

  17-12-2025 17:12 via drugs.com
  WEDNESDAY, Dec. 17, 2025 -- Sports injuries do not occur more often during menstruation, but those sustained during menstruation have a significantly higher burden, according to a study published online Dec. 16 in Frontiers in Sports and Active...
  
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• SABCS: Risk-Based Screening Noninferior for Identifying Stage ≥IIB Breast Cancer

  17-12-2025 17:12 via drugs.com
  WEDNESDAY, Dec. 17, 2025 -- Risk-based screening, including genetic testing, is noninferior to annual screening for detecting stage ≥IIB cancers and does not reduce biopsy rates despite fewer mammograms, according to a study published online Dec...
  
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• Ketamine Versus Etomidate to Induce Anesthesia Does Not Cut Death in Critically Ill

  17-12-2025 17:12 via drugs.com
  WEDNESDAY, Dec. 17, 2025 -- Use of ketamine to induce anesthesia does not result in lower in-hospital death by day 28 compared with etomidate among critically ill adults undergoing tracheal intubation, according to a study published online Dec. 9 in...
  
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• GLP-1 Receptor Agonist Use May Lower Vertebral Fracture Risk With Type 2 Diabetes

  17-12-2025 17:12 via drugs.com
  WEDNESDAY, Dec. 17, 2025 -- Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) may protect against vertebral fractures in people with diabetes, according to a research letter published online Dec. 10 in JAMA Surgery.
  Wei-Thing Khor, M.D., from...
  
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• Expectant Management Matches Active Treatment in Preemies With Patent Ductus Arteriosus

  17-12-2025 17:12 via drugs.com
  WEDNESDAY, Dec. 17, 2025 -- For extremely preterm infants with protocol-defined patent ductus arteriosus (PDA), the incidence of death or bronchopulmonary dysplasia (BPD) does not differ with expectant management versus active treatment, according...
  
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• EACVI: Severe Valvular Heart Disease Prevalent Among Patients With Cancer

  17-12-2025 17:12 via drugs.com
  WEDNESDAY, Dec. 17, 2025 -- Severe valvular heart disease (VHD) is prevalent among patients with cancer and is associated with reduced survival, according to a study presented at the annual congress of the European Association of Cardiovascular...
  
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• Body Dissatisfaction Linked to Eating Disorder, Depressive Symptoms

  17-12-2025 17:12 via drugs.com
  WEDNESDAY, Dec. 17, 2025 -- Body dissatisfaction may causally increase eating disorder and depressive symptoms, according to a study published in the January issue of The Lancet Psychiatry.
  Ilaria Costantini, Ph.D., from University College London...
  
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• American Society of Hematology, Dec. 6 to 9

  17-12-2025 12:21 via drugs.com
  The annual meeting of the American Society of Hematology was held from Dec. 6 to 9 in Orlando, Florida, and attracted participants from around the world, including hematology specialists as well as clinical practitioners and other health care...
  
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