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Real-World Outcomes Favor Standard Care in HER2-Positive Metastatic Breast Cancer
via medpagetoday.com(MedPage Today) -- At the San Antonio Breast Cancer Symposium (SABCS), a large retrospective analysis of U.S. electronic health records compared outcomes for patients with HER2-positive metastatic breast cancer who received first-line guideline... -
Novel Oral Antibiotic Matches Standard Option for Urogenital Gonorrhea
via medpagetoday.com(MedPage Today) -- Investigational zoliflodacin was noninferior to standard therapy with ceftriaxone plus azithromycin in treating uncomplicated urogenital gonorrhea, an international phase III randomized trial showed.
Among over 900 patients... -
First At-Home Device Approved for Depression
via medpagetoday.com(MedPage Today) -- The FDA on Thursday approved a transcranial direct current stimulation (tDCS) device as the first at-home non-drug therapy for major depression in adults, maker Flow Neuroscience announced.
Dubbed FL-100, the prescription headset... -
Senate Rejects Extension of Obamacare Subsidies
via medpagetoday.com(MedPage Today) -- The Senate on Thursday rejected legislation to extend Affordable Care Act (ACA) tax credits, essentially guaranteeing that millions of Americans will see a steep rise in costs in 2026.
Senators rejected a Democratic bill to... -
Senators Urge More Localized Use of Donor Organs
via medpagetoday.com(MedPage Today) -- More needs to be done to make sure donated organs are transplanted to recipients within the local geographic area whenever possible, several senators said Thursday at a hearing on the future of the organ procurement and transplantation... -
GLP-1 Drugs Linked to Lower Epilepsy Risk in Diabetes Patients
via medpagetoday.com(MedPage Today) -- GLP-1 receptor agonists were tied to a lower risk of developing epilepsy in adults with type 2 diabetes, a large U.S. study showed.
Compared with DPP-4 inhibitors, GLP-1 receptor agonist use was associated with a 16% lower risk... -
FDA Approves New Type of Antibiotic for Gonorrhea, First in Decades
via medpagetoday.com(MedPage Today) -- The FDA approved gepotidacin (Blujepa), an oral option for the treatment of uncomplicated urogenital gonorrhea among patients ages 12 years and older, GSK announced on Thursday.
Gepotidacin is the first in a new class of antibiotics... -
RFK Jr.’s Former Group Urges FDA to Revoke COVID Vax Licenses
via medpagetoday.com(MedPage Today) -- An anti-vaccine organization founded by HHS Secretary Robert F. Kennedy Jr. is urging the FDA he now oversees to pull the licenses of Pfizer's and Moderna's COVID-19 vaccines.
Children's Health Defense (CHD) filed a citizen... -
Florida Sues Medical Groups Over Youth Gender-Affirming Care
via medpagetoday.com(MedPage Today) -- Florida Attorney General James Uthmeier targeted three major medical organizations in a lawsuit over gender-affirming care for youth.
The lawsuit alleges that the World Professional Association for Transgender Health (WPATH... -
Uterine Fibroids Point to Risk of Heart Disease Down the Line
via medpagetoday.com(MedPage Today) -- Women with uterine fibroids were more prone to atherosclerotic cardiovascular disease (ASCVD), according to observational research.
Based on a large study of the commercially insured U.S. population, there was an uptick in incident... -
RFK Jr.'s Viral Pull-Ups; Docs Denounce ACIP's Hep B Vote; 'Don't Pee!'
via medpagetoday.com(MedPage Today) -- The following contains links to social media websites including Bluesky, X, TikTok, Instagram, Facebook, and LinkedIn.
"Even if he did have good form and full reps, he'd still be an absolute joke," said obesity medicine physician... -
Blood Clots in Ulcerative Colitis; AI Tool for MASH; Stomach Cancer Screening?
via medpagetoday.com(MedPage Today) -- Risk of venous thromboembolism and cardiovascular events in ulcerative colitis (UC) patients on advanced therapies were lower with vedolizumab (Entyvio) compared with TNF inhibitors in a real-world analysis from Japan; the study... -
ADC Post-Endocrine Therapy Misses Mark in Advanced Breast Cancer Trial
via medpagetoday.com(MedPage Today) -- SAN ANTONIO--The antibody-drug conjugate (ADC) sacituzumab govitecan (Trodelvy) failed to outperform chemotherapy as first treatment after endocrine therapy for metastatic hormone receptor-positive/HER2-negative breast cancer... -
FDA Proposes Allowing New Sunscreen Ingredient
via medpagetoday.com(MedPage Today) -- The FDA has proposed adding bemotrizinol as a new active ingredient allowed in sunscreens, in a move it says will "advance sunscreen innovation."
This move is part of a broader initiative in the Office of Nonprescription Drugs... -
Expand Labeling for Testosterone Replacement Therapy, FDA Panel Says
via medpagetoday.com(MedPage Today) -- Members of an FDA expert panel urged the agency to expand labeling for testosterone replacement therapy and remove its classification as a controlled substance.
Like previous FDA expert panels, the group was convened by Commissioner... -
RFK Jr. Tops This Year's Shkreli Awards
via medpagetoday.com(MedPage Today) -- HHS Secretary Robert F. Kennedy Jr. took the top spot in this year's Shkreli Awards from the Lown Institute.Kennedy's act beat out pharma-owned institutional review boards (IRBs), problematic $29,500 lab-grown arteries, pricey... -
Should Congress Intervene in the Newborn Hep B Vaccine Controversy?
via medpagetoday.com(MedPage Today) -- On December 5, the Advisory Committee on Immunization Practices (ACIP) didn't just change a vaccine recommendation; they presided over an impending public health travesty. In a decision breathtaking in its shamelessness, the... -
Triplet Delays Breast Cancer Progression in First-Line Maintenance Setting
via medpagetoday.com(MedPage Today) -- SAN ANTONIO--Adding tucatinib (Tukysa) to first-line maintenance therapy with trastuzumab and pertuzumab (Perjeta) significantly improved progression-free survival (PFS) in patients with HER2-positive metastatic breast cancer... -
Gender Care Docs Accused of Fraud; Army Ob/Gyn Criminally Charged; Nurse Sentenced
via medpagetoday.com(MedPage Today) -- Texas Attorney General Ken Paxton has accused two doctors of fraudulently billing Medicaid to provide gender-affirming care. May Lau, MD, and M. Brett Cooper, MD, were both sued by Paxton last year for allegedly violating the... -
U.S. Suicide Rate Fell in 2024 After Hovering at High Level
via medpagetoday.com(MedPage Today) -- The U.S. suicide rate dropped slightly last year from some of the highest levels ever reported, preliminary data suggests. Experts say it's hard to know exactly why, or whether the decline will continue.
A little over 48,800... -
Gene Therapy-Induced CAR T Cells for Myeloma Could Alter Treatment Landscape
via medpagetoday.com(MedPage Today) -- ORLANDO--A gene therapy that could transform CAR T-cell treatment achieved rapid and potentially durable measurable residual disease (MRD)-negative responses in the first four patients with relapsed/refractory multiple myeloma... -
Outbreak Hospitalizes 51; Cardiologist Attacked; Birth in a Self-Driving Car
via medpagetoday.com(MedPage Today) --Note that some links may require registration or subscription.
The multi-state infant botulism outbreak related to ByHeart Whole Nutrition infant formula has reached 51 cases, according to an FDA alert.
The World Health Organization... -
UK pledges to spend extra £1.5bn on NHS medicines as part of Trump tariff deal
Outlay over next 3 years is in return for the US exempting British pharmaceutical imports from tariffs -
One Antidepressant Deprescribing Strategy Topped Others in Preventing Relapse
via medpagetoday.com(MedPage Today) -- Slow tapering of antidepressants with psychological support was as effective as antidepressant continuation in preventing relapse among patients with remitted depression, a systematic review and network meta-analysis of randomized... -
Next-Gen SERD Cuts Breast Cancer Recurrence Risk by 30% in Trial
via medpagetoday.com(MedPage Today) -- SAN ANTONIO--In a large phase III trial of adjuvant treatment for early-stage breast cancer, the investigational oral drug giredestrant reduced the risk of invasive disease recurrence by 30% versus standard endocrine therapy... -
New York Times Says It Won't Be Deterred From Writing About Trump's Health
via medpagetoday.com(MedPage Today) -- The New York Times, attacked by President Donald Trump for reporting about his physical condition, said on Wednesday that it wouldn't be deterred by "false and inflammatory language" that distorts the role of a free press.
The... -
How Do We Know Aluminum Adjuvants in Vaccines Are Safe?
via medpagetoday.com(MedPage Today) -- HHS Secretary Robert F. Kennedy Jr.'s vaccine advisors have set their sights on aluminum adjuvants in vaccines as part of their review of the U.S. pediatric vaccine schedule.
While the concept of injecting a metal into children... -
Partisan Politics Sidetrack House Hearing on Healthcare Tech Costs
via medpagetoday.com(MedPage Today) -- A House hearing Wednesday on the topic of how technology can help lower healthcare costs was sidetracked almost immediately by partisan politics.
"Healthcare costs of the United States have long been on the rise, but recent... -
Gene Therapy Wins FDA Approval for Life-Threatening Immunodeficiency
via medpagetoday.com(MedPage Today) -- The FDA on Tuesday approved etuvetidigene autotemcel (Waskyra) as the first cell-based gene therapy for patients 6 months and older with Wiskott-Aldrich syndrome, a rare primary immunodeficiency.
The life-threatening genetic... -
House Democrat Files Articles of Impeachment Against RFK Jr.
via medpagetoday.com(MedPage Today) -- Rep. Haley Stevens (D-Mich.) announced that she introduced articles of impeachment against HHS Secretary Robert F. Kennedy Jr. on Wednesday.
The articles of impeachment contend that Kennedy "has imperiled the health and safety...
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