(MedPage Today) -- For tracheal intubation anesthesia in critically ill patients, ketamine didn't improve survival compared with etomidate, a pragmatic clinical trial showed.
In-hospital death by day 28 occurred in 28.1% of ketamine-treated patients...
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Ketamine Not a Better Anesthetic for Intubation of Critically Ill Patients
via medpagetoday.com
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Outbreak Hospitalizes 51; Cardiologist Attacked; Birth in a Self-Driving Car
via medpagetoday.com(MedPage Today) --Note that some links may require registration or subscription.
The multi-state infant botulism outbreak related to ByHeart Whole Nutrition infant formula has reached 51 cases, according to an FDA alert.
The World Health Organization...
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UK pledges to spend extra £1.5bn on NHS medicines as part of Trump tariff deal
Outlay over next 3 years is in return for the US exempting British pharmaceutical imports from tariffs
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One Antidepressant Deprescribing Strategy Topped Others in Preventing Relapse
via medpagetoday.com(MedPage Today) -- Slow tapering of antidepressants with psychological support was as effective as antidepressant continuation in preventing relapse among patients with remitted depression, a systematic review and network meta-analysis of randomized...
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Next-Gen SERD Cuts Breast Cancer Recurrence Risk by 30% in Trial
via medpagetoday.com(MedPage Today) -- SAN ANTONIO--In a large phase III trial of adjuvant treatment for early-stage breast cancer, the investigational oral drug giredestrant reduced the risk of invasive disease recurrence by 30% versus standard endocrine therapy...
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New York Times Says It Won't Be Deterred From Writing About Trump's Health
via medpagetoday.com(MedPage Today) -- The New York Times, attacked by President Donald Trump for reporting about his physical condition, said on Wednesday that it wouldn't be deterred by "false and inflammatory language" that distorts the role of a free press.
The...
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How Do We Know Aluminum Adjuvants in Vaccines Are Safe?
via medpagetoday.com(MedPage Today) -- HHS Secretary Robert F. Kennedy Jr.'s vaccine advisors have set their sights on aluminum adjuvants in vaccines as part of their review of the U.S. pediatric vaccine schedule.
While the concept of injecting a metal into children...
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Partisan Politics Sidetrack House Hearing on Healthcare Tech Costs
via medpagetoday.com(MedPage Today) -- A House hearing Wednesday on the topic of how technology can help lower healthcare costs was sidetracked almost immediately by partisan politics.
"Healthcare costs of the United States have long been on the rise, but recent...
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Gene Therapy Wins FDA Approval for Life-Threatening Immunodeficiency
via medpagetoday.com(MedPage Today) -- The FDA on Tuesday approved etuvetidigene autotemcel (Waskyra) as the first cell-based gene therapy for patients 6 months and older with Wiskott-Aldrich syndrome, a rare primary immunodeficiency.
The life-threatening genetic...
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House Democrat Files Articles of Impeachment Against RFK Jr.
via medpagetoday.com(MedPage Today) -- Rep. Haley Stevens (D-Mich.) announced that she introduced articles of impeachment against HHS Secretary Robert F. Kennedy Jr. on Wednesday.
The articles of impeachment contend that Kennedy "has imperiled the health and safety...
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Bone Fractures Down With GLP-1 Drugs in the Picture
via medpagetoday.com(MedPage Today) -- Beyond their established cardiometabolic benefits, GLP-1 receptor agonists also may be tied to improved bone health, based on an observational report.
Adults with type 2 diabetes on GLP-1 agonists tended to have small but significant...
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Lab-Based Tool Identifies Febrile Infants With Invasive Bacterial Infections
via medpagetoday.com(MedPage Today) -- A three-part prediction tool using laboratory tests without lumbar puncture rule demonstrated high sensitivity but limited specificity for identifying febrile infants ages 28 days or younger with invasive bacterial infections...
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SCOTUS May Impede State Investigations Into Crisis Pregnancy Centers
via medpagetoday.com(MedPage Today) -- An ongoing Supreme Court case may upend states' ability to investigate deceptive healthcare organizations.
When an entity is engaging in fraudulent or deceptive practices that pose a risk to consumers' health and safety, states...
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Watch Out for Bleeding in These Cancer Patients on Extended Anticoagulation
via medpagetoday.com(MedPage Today) -- ORLANDO--Researchers identified four predictors of clinically relevant bleeding in patients receiving extended anticoagulation with apixaban (Eliquis) for cancer-associated venous thromboembolism (VTE).
Over a median follow...
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Gene Therapy Maintains Efficacy in Hemophilia B Out to 5 Years
via medpagetoday.com(MedPage Today) -- ORLANDO--Patients with hemophilia B continued to experience low annualized bleeding rates and stable endogenous factor IX expression 5 years after a single infusion of etranacogene dezaparvovec (Hemgenix), the final analysis...
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FDA Opens Safety Review of Injectable RSV Drugs Approved for Babies and Toddlers
via medpagetoday.com(MedPage Today) -- FDA officials opened a safety review of two injectable drugs used to protect babies and toddlers from RSV, the respiratory virus that sends thousands of American children to the hospital each year.
The long-acting drugs from...
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ACIP Chair's Hot Mic; Don't Deny COVID Vax Deaths; Abortion Drug Study Stalled
via medpagetoday.com(MedPage Today) -- Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week.
ACIP Chair's Hot Mic
The new chair of the CDC's Advisory Committee on Immunization Practices...
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ACIP Chair's Hot Mic; Don't Deny COVID Vax Deaths; Abortion Drug Review Stalled
via medpagetoday.com(MedPage Today) -- Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week.
ACIP Chair's Hot Mic
The new chair of the CDC's Advisory Committee on Immunization Practices...
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Phase I Vaccine Trial Shows Promise for Preventing Triple-Negative Breast Cancer
via medpagetoday.com(MedPage Today) -- At the San Antonio Breast Cancer Symposium (SABCS), investigators reported final phase I results of an alpha-lactalbumin (aLA) vaccine designed to help prevent triple-negative breast cancer (TNBC), particularly among women at...
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AI Model Improves Prediction of Early and Late Breast Cancer Recurrence
via medpagetoday.com(MedPage Today) -- At the San Antonio Breast Cancer Symposium, researchers presented a study on a multimodal artificial intelligence model that integrated clinical data, pathology-based imaging, and expanded molecular profiling to improve prediction...
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COVID Vax Death Probe Expands; Eggs Recalled; Med School Enrollment Up
via medpagetoday.com(MedPage Today) -- Note that some links may require registration or subscription.
The FDA expanded its scrutiny of COVID-19 vaccines in children to investigate whether adult deaths were linked to the shots. (Washington Post via MSN)
A Northern...
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Real-World Outcomes Favor Standard Care in HER2-Positive Metastatic Breast Cancer
via medpagetoday.com(MedPage Today) -- At the San Antonio Breast Cancer Symposium (SABCS), a large retrospective analysis of U.S. electronic health records compared outcomes for patients with HER2-positive metastatic breast cancer who received first-line guideline...
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Number of Hospitals Equipped to Handle Pediatric Cases on the Decline
via medpagetoday.com(MedPage Today) -- The number of U.S. hospitals equipped to handle pediatric cases fell over two decades, data from the Healthcare Cost and Utilization Project Kids' Inpatient Database showed.
From 2003 to 2022, the proportion of hospitals with...
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The world is losing immunity to superbugs, but we can rebuild it
The evidence base for reversing drug resistance is there: measure results, learn from failures and stay the course
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Explainer: Chagas disease spreads to richer countries
Untreated infection can lead to heart disease and other disorders decades later
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Energy Drinks Blamed for Man's Severe High Blood Pressure, Stroke
via medpagetoday.com(MedPage Today) -- Excessive energy drink consumption may explain a person's hypertension and stroke, as illustrated by a case report from England.
A man in his 50s, otherwise fit and healthy, presented with sudden left-sided numbness and unsteadiness...
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Rare Temporary Flu Complication Can Leave Some Kids Unable to Walk
via medpagetoday.com(MedPage Today) -- Welcome to Culture Clinic, MedPage Today's collaboration with Northwell Health to offer a healthcare professional's take on the latest viral medical topics.
A 9-year-old girl in Michigan recently made the news after suddenly...
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Material Hardship, 'Catastrophic' Income Loss Common in Families of Kids With ALL
via medpagetoday.com(MedPage Today) -- ORLANDO--Almost a third of families of children with newly diagnosed acute lymphocytic leukemia (ALL) had housing or food-related hardships or "catastrophic" income loss during standard chemotherapy, according to a study...
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How a Rare Drug Made From Scientists' Blood Saves Babies From Botulism
via medpagetoday.com(MedPage Today) -- When Alessandro Barbera was rushed to a California hospital with infant botulism in October, his father had barely heard of the disease, never mind the rare and costly treatment that likely saved the newborn's life.
Now, however...
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Cheap Drug During High-Risk Surgery Reduces Blood Transfusions
via medpagetoday.com(MedPage Today) -- ORLANDO--A hospital policy to increase the use of perioperative tranexamic acid (TXA) reduced blood transfusions during major noncardiac surgeries with no apparent impact on clotting events, a cluster randomized trial from...
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