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-
Bispecific Trial in Myeloma Sparks Talks of 'Functional Cure'
via medpagetoday.com(MedPage Today) -- ORLANDO--Combining teclistamab (Tecvayli) with subcutaneous daratumumab-hyaluronidase (Darzalex Faspro) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with relapsed/refractory... -
Winter Virus Season Not Too Bad So Far, but Docs Worry About Suffering to Come
via medpagetoday.com(MedPage Today) -- It may feel like you are surrounded by sniffles and coughs, but flu season activity is still low in many parts of the U.S.
New government data posted Friday shows that as of last week, flu activity was high in four states... -
Survival Is Possible With Resuscitation in Some Infants Born Alive at 21 Weeks
via medpagetoday.com(MedPage Today) -- More than a third of resuscitated infants born alive at 21 weeks' gestational age--an age previously believed to be previable--survived to discharge, a single-center, retrospective case series showed.
Among 22 infants... -
Survival Is Possible With Resuscitation in Some Extremely Premature Infants
via medpagetoday.com(MedPage Today) -- More than a third of resuscitated infants born alive at 21 weeks' gestational age--an age previously believed to be previable--survived to discharge, a single-center, retrospective case series showed.
Among 22 infants... -
CDC Says Kids' COVID Shots Reduced Emergency Department Visits
via medpagetoday.com(MedPage Today) -- COVID vaccines for the 2024-2025 season provided protection against COVID-associated emergency department (ED) and urgent care visits among children, according to data from a multisite electronic health record-based network... -
Anticoagulant Reversal Drug Pulled From U.S. Market
via medpagetoday.com(MedPage Today) -- Andexanet alfa (Andexxa) will officially be taken off the U.S. market this month as an emergency reversal medication for contemporary blood thinners.
"The Biologics License Application for Andexxa has been withdrawn for commercial... -
Ianalumab's Success in Phase III Trials Marks a Turning Point in Sjogren's Disease
via medpagetoday.com(MedPage Today) -- In the recently reported NEPTUNUS-1 and -2 trials, presented at this year's American College of Rheumatology (ACR) annual meeting, investigators found that the anti-B-cell activating factor receptor (BAFF-R) antibody ianalumab... -
Trial Makes the Case for Replacing Annual Breast Cancer Screening
via medpagetoday.com(MedPage Today) -- SAN ANTONIO--Risk-based breast cancer screening proved noninferior for detecting clinically significant tumors in a randomized trial, though outside experts raised concerns and a major medical group said the findings do not... -
Study Makes the Case for Replacing Annual Breast Cancer Screening
via medpagetoday.com(MedPage Today) -- SAN ANTONIO--Risk-based breast cancer screening proved noninferior for detecting clinically significant tumors in a randomized trial, though outside experts raised concerns and a major medical group said the findings do not... -
Some Health Plans Automatically Downcode Office Visit Claims
via medpagetoday.com(MedPage Today) -- Several insurers are automatically downcoding--and, therefore, paying less for--claims for non-procedural office visits, a practice that provider groups said is unfair and may be anticompetitive.
The claims involved... -
Myasthenia Gravis Gets a New Drug Approval
via medpagetoday.com(MedPage Today) -- The FDA expanded the indication of inebilizumab (Uplizna) to include generalized myasthenia gravis (gMG), Amgen announced Friday.
The drug is now approved to treat gMG in adults who are anti-acetylcholine receptor (AChR) or... -
The King's Cancer Speech; Multiple Studies Retracted; Mass Sperm Donor Had TP53 Gene
via medpagetoday.com(MedPage Today) -- King Charles III shared a personal message about his experience with cancer and encouraged others to get screened in a prerecorded video message airing on British television. (AP)
Alcohol intake, particularly at higher frequency... -
Lowering FDA's Drug-Approval Standards Is a Lose-Lose
via medpagetoday.com(MedPage Today) -- Last week, FDA Commissioner Marty Makary, MD, MPH, announced plans to officially lower the standard for how many clinical trials are needed to approve a new drug--from the long-standing expectation of at least two trials... -
More Support for Omitting Lymph Node Biopsy in Low-Risk Early Breast Cancer
via medpagetoday.com(MedPage Today) -- SAN ANTONIO--Many patients with early breast cancer can safely skip sentinel lymph node biopsy (SLNB), results of a large Dutch study suggested.
After 5 years, the regional recurrence-free survival (RRFS) rate was 96.6... -
What Trump's Cognitive Tests Can -- and Can't -- Reveal
via medpagetoday.com(MedPage Today) -- In a late-night keyboard marathon this week, President Donald Trump fired off a post on Truth Social announcing he "aced" his third cognitive test.
"In addition to the Medical [tests], I have done something that no other President... -
Novel Therapies in IgA Nephropathy Bring New Options, and New Questions
via medpagetoday.com(MedPage Today) -- Clinicians face exciting new options in immunoglobulin A (IgA) nephropathy, with recent accelerated FDA approvals and positive data presented on agents targeting B-cell activating factor (BAFF) and a proliferation-inducing ligand... -
Pre-Op MRI Shows 'No Clinical Benefit' in Early Breast Cancer
via medpagetoday.com(MedPage Today) -- SAN ANTONIO--Preoperative MRI for staging patients with early, hormone receptor (HR)-negative breast cancer didn't result in improved oncologic outcomes or improved clinical care, according to a phase III study presented... -
Taylor Swift Fans' 'Joy Blackouts' Are Completely Normal
via medpagetoday.com(MedPage Today) -- In an appearance on "The Late Show With Stephen Colbert" on Wednesday night, Taylor Swift described how fans who attended shows during her Eras Tour experienced "joy blackouts"--they couldn't remember large swaths of the... -
Amid Uproar, Lawmakers Push to Add Nursing to 'Professional' Programs List
via medpagetoday.com(MedPage Today) -- A bipartisan group in Congress is urging the Education Department to add nursing to a list of college programs that are considered "professional," adding to public outcry after nurses were omitted from a new agency definition... -
EHR Giant Sued; Black Box Warning for COVID Shots; Liam Neeson Narrates Anti-Vax Doc
via medpagetoday.com(MedPage Today) -- Note that some links may require registration or subscription.
Attorney General Ken Paxton announced a lawsuit against Epic Systems that claims the electronic health record (EHR)-giant has an unlawful monopoly and restricts... -
Pills May Represent the Next Wave in Psoriasis Treatment
via medpagetoday.com(MedPage Today) -- For many patients with psoriasis, the delivery method matters just as much as the efficacy. While topicals and biologics remain effective and widely used, oral formulations have long represented an unmet need--until now... -
Novel Oral Antibiotic Matches Standard Option for Urogenital Gonorrhea
via medpagetoday.com(MedPage Today) -- Investigational zoliflodacin was noninferior to standard therapy with ceftriaxone plus azithromycin in treating uncomplicated urogenital gonorrhea, an international phase III randomized trial showed.
Among over 900 patients... -
First At-Home Device Approved for Depression
via medpagetoday.com(MedPage Today) -- The FDA on Thursday approved a transcranial direct current stimulation (tDCS) device as the first at-home non-drug therapy for major depression in adults, maker Flow Neuroscience announced.
Dubbed FL-100, the prescription headset... -
Senate Rejects Extension of Obamacare Subsidies
via medpagetoday.com(MedPage Today) -- The Senate on Thursday rejected legislation to extend Affordable Care Act (ACA) tax credits, essentially guaranteeing that millions of Americans will see a steep rise in costs in 2026.
Senators rejected a Democratic bill to... -
Senators Urge More Localized Use of Donor Organs
via medpagetoday.com(MedPage Today) -- More needs to be done to make sure donated organs are transplanted to recipients within the local geographic area whenever possible, several senators said Thursday at a hearing on the future of the organ procurement and transplantation... -
GLP-1 Drugs Linked to Lower Epilepsy Risk in Diabetes Patients
via medpagetoday.com(MedPage Today) -- GLP-1 receptor agonists were tied to a lower risk of developing epilepsy in adults with type 2 diabetes, a large U.S. study showed.
Compared with DPP-4 inhibitors, GLP-1 receptor agonist use was associated with a 16% lower risk... -
FDA Approves New Type of Antibiotic for Gonorrhea, First in Decades
via medpagetoday.com(MedPage Today) -- The FDA approved gepotidacin (Blujepa), an oral option for the treatment of uncomplicated urogenital gonorrhea among patients ages 12 years and older, GSK announced on Thursday.
Gepotidacin is the first in a new class of antibiotics... -
RFK Jr.’s Former Group Urges FDA to Revoke COVID Vax Licenses
via medpagetoday.com(MedPage Today) -- An anti-vaccine organization founded by HHS Secretary Robert F. Kennedy Jr. is urging the FDA he now oversees to pull the licenses of Pfizer's and Moderna's COVID-19 vaccines.
Children's Health Defense (CHD) filed a citizen... -
Florida Sues Medical Groups Over Youth Gender-Affirming Care
via medpagetoday.com(MedPage Today) -- Florida Attorney General James Uthmeier targeted three major medical organizations in a lawsuit over gender-affirming care for youth.
The lawsuit alleges that the World Professional Association for Transgender Health (WPATH... -
Uterine Fibroids Point to Risk of Heart Disease Down the Line
via medpagetoday.com(MedPage Today) -- Women with uterine fibroids were more prone to atherosclerotic cardiovascular disease (ASCVD), according to observational research.
Based on a large study of the commercially insured U.S. population, there was an uptick in incident...
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