(MedPage Today) -- Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week.
ACIP Chair's Hot Mic
The new chair of the CDC's Advisory Committee on Immunization Practices...
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ACIP Chair's Hot Mic; Don't Deny COVID Vax Deaths; Abortion Drug Review Stalled
via medpagetoday.com -
Lung Cancer Screening Follow-Up Often Inadequate
via medpagetoday.com(MedPage Today) -- After finding abnormalities on low-dose CT lung cancer screening, many patients don't get the recommended level of follow-up care, a Medicare-linked registry analysis showed.
Only 59.7% of such patients received guideline-concordant... -
Blockbuster Drug Lands First-Line Indication for HER2-Positive Breast Cancer
via medpagetoday.com(MedPage Today) -- The FDA approved trastuzumab deruxtecan (T-DXd; Enhertu) in combination with pertuzumab (Perjeta) for the first-line treatment of adults with unresectable or metastatic HER2-positive breast cancer.
Approval was based on results... -
Second Oral Antibiotic for Gonorrhea Gets FDA Green Light
via medpagetoday.com(MedPage Today) -- The FDA on Friday announced approval of zoliflodacin (Nuzolvence) as an oral treatment for gonorrhea, a day after approving oral gepotidacin (Blujepa) for the same indication.
Zoliflodacin is the first of a new class of antibiotics... -
Women Getting Bad Advice on Cannabis Use in Pregnancy, Study Finds
via medpagetoday.com(MedPage Today) -- While most cannabis retailers recommended women not use blunts or tobacco while pregnant, about one in five suggested prenatal cannabis use was safe, according to a cross-sectional study of California retailers.
Out of 505 cannabis... -
Burden of Postpartum Hemorrhage May Be Greater Than Previously Thought
via medpagetoday.com(MedPage Today) -- Rates of postpartum hemorrhage and severe postpartum hemorrhage were markedly higher with the use of objective blood loss assessment methods, suggesting that subjective assessment methods may be underestimating the prevalence... -
Look to the States to Lead on Public Health
via medpagetoday.com(MedPage Today) -- The scientifically unsound "Make America Healthy Again" (MAHA) initiative is devastating our country's scientific infrastructure, medical research capacity, epidemiologic surveillance, and public health response capacity. MAHA... -
Walking Away With Purpose …
via medpagetoday.com(MedPage Today) -- Editor's Note: This will be David Nash's final "Focus on Policy" column for MedPage Today. Nash has been a pioneer in the field of population health, pushing for its recognition years before anyone else was paying attention... -
Myeloma Combination Cuts Line for FDA Approval After Strong ASH Results
via medpagetoday.com(MedPage Today) -- Under a program designed to accelerate the approval of products that could address key national priorities, the FDA awarded a national priority voucher to teclistamab (Tecvayli) in combination with daratumumab (Darzalex) for... -
Akeega Approved for BRCA2-Mutated Prostate Cancer
via medpagetoday.com(MedPage Today) -- The FDA approved niraparib and abiraterone acetate (Akeega) in combination with prednisone for treating BRCA2-mutated metastatic castration-sensitive prostate cancer (mCSPC), the agency announced on Friday.
The once-daily, fixed... -
Etripamil Gets FDA Approval for At-Home Tachycardia Conversion
via medpagetoday.com(MedPage Today) -- The FDA approved etripamil (Cardamyst) nasal spray for at-home treatment of paroxysmal supraventricular tachycardia (PSVT), maker Milestone Pharmaceuticals announced.
The rapid-acting L-type calcium channel blocker is indicated... -
Novel Pills Promising in Relapsed/Refractory Multiple Myeloma
via medpagetoday.com(MedPage Today) -- All-oral therapies provide an attractive treatment option for patients with relapsed/refractory multiple myeloma, given their administration, the convenience of outpatient dosing, and the decreased need for hospital visits.... -
Longevity Forever!
via medpagetoday.com(MedPage Today) -- "So, Dr. Pelzman, can you tell me what I should do about all this stuff?"
I've written before about patients who've seen outside providers and then bring us their results to interpret, as well as patients who see specialists... -
Outcomes Remain Poor in Blast-Phase CML, Despite Modern TKIs
via medpagetoday.com(MedPage Today) -- At the recent American Society of Hematology annual meeting, researchers presented real-world outcomes for patients with blast-phase chronic myeloid leukemia (CML) using data from a multi-institution U.S. cohort.
In this MedPage... -
Awareness of BRCA Status Drives Aggressive Surgery in Early-Onset Breast Cancer
via medpagetoday.com(MedPage Today) -- At the San Antonio Breast Cancer Symposium, investigators from an international consortium reported that knowledge of BRCA1/2 mutation status strongly influenced surgical decision-making in young patients with stages I-III breast... -
House Speaker Unveils Healthcare Plan as Divided GOP Scrambles for an Alternative
via medpagetoday.com(MedPage Today) -- The Senate failed to get anywhere on healthcare last week. Now it's the House's turn to show what it can do.
Speaker Mike Johnson (R-La.) unveiled a Republican alternative late Friday, a last-minute sprint as his party refuses... -
Woman’s Ice-Skating Fall Produces Striking X-Ray, Rare Forearm Break
via medpagetoday.com(MedPage Today) -- The weather outside might be frightful--but so is a radiograph of the arm one woman broke while ice skating.
The 26-year-old arrived at the emergency department at Far Eastern Memorial Hospital in Taipei City, Taiwan, with... -
Are Our Patients Underestimating the Incidence and Impact of Shingles?
via medpagetoday.com(MedPage Today) -- Girgis is a paid spokesperson for GSK.
As doctors, we advise our patients to get their mammograms, schedule their colon cancer screenings, and get their annual influenza vaccines. Preventing shingles should be on that same list... -
Smart Pill Bottle Boosts Adherence to Endocrine Therapy in Early Breast Cancer
via medpagetoday.com(MedPage Today) -- At the San Antonio Breast Cancer Symposium, researchers reported that real-time monitoring with smart pill bottles significantly improved adherence to adjuvant endocrine therapy compared with standard-of-care monitoring.
In... -
Fellow Nurses: Is Nursing Weighing You Down … Literally?
via medpagetoday.com(MedPage Today) -- Long shifts, short staffing, and families who think "the call light is a suggestion" ... it's no wonder many nurses end the day clutching a vending-machine pastry like it's a life raft. When you're tired and stressed, a donut... -
The King's Cancer Update; VA to Slash Thousands of Health Jobs; 2025's Top Research
via medpagetoday.com(MedPage Today) -- Note that some links may require registration or subscription.
Crediting early detection, King Charles III said that treatment for his undisclosed type of cancer will be reduced in the new year and encouraged others to get screened... -
Preop RT May Boost Response to Chemo-Immunotherapy in High-Risk Early Breast Cancer
via medpagetoday.com(MedPage Today) -- SAN ANTONIO--Preoperative radiotherapy (RT) plus PD-1 inhibitor pembrolizumab (Keytruda) significantly increased immune activation and tumor response in node-positive hormone receptor-positive (HR+)/HER2-negative breast cancer... -
'Terrible Distortion of All the Facts': What We Heard This Week
via medpagetoday.com(MedPage Today) -- "What you have said is a terrible, terrible distortion of all the facts."--CDC Advisory Committee on Immunization Practices (ACIP) member Cody Meissner, MD, of Dartmouth College in Hanover, New Hampshire, responding to a... -
I Co-Discovered HIV. Here Are Lessons to Help Prepare for the Next Threat.
via medpagetoday.com(MedPage Today) -- Science progresses when people share what they learn, not when they retreat behind borders or institutions.
That was true when my colleagues and I first discovered a protein, known today as interleukin-2, which enabled growth... -
No Increased Breast Cancer Risk With Menopausal Estrogen in BRCA Carriers
via medpagetoday.com(MedPage Today) -- SAN ANTONIO--Menopausal hormone therapy (MHT) did not increase breast cancer risk in women with BRCA mutations, according to a study reported here.
In fact, women who used estrogen-only MHT had a significantly lower risk... -
How Were GLP-1 Drugs and Bone Health Linked?
via medpagetoday.com(MedPage Today) -- You passed medical training, now see if you can pass our weekly quiz -
Pain and Functioning; AI Decision Support for Stroke Treatment
via medpagetoday.com(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of Texas Tech Health El Paso, look at the top medical... -
Fragile Students Won't Last in Medicine
via medpagetoday.com(MedPage Today) -- When I first read about the Samantha Fulnecky and Mel Curth debacle that captivated the nation last week, I thought: "Well that's the most creative grade negotiation I've ever seen."
Fulnecky, a pre-med junior at University... -
Florida Plows Ahead on Push to Roll Back Certain Vaccine Mandates for Schoolchildren
via medpagetoday.com(MedPage Today) -- Florida officials are plowing ahead with a proposal to roll back certain vaccine mandates for the state's schoolchildren, after Republican Gov. Ron DeSantis called for the state to become the first in the nation to eliminate... -
One GLP-1 Drug May Be Better Than Rivals for Glaucoma Risk
via medpagetoday.com(MedPage Today) -- Use of the dual GIP/GLP-1 drug tirzepatide (Mounjaro, Zepbound) was associated with a significantly reduced risk of glaucoma compared with GLP-1 drugs among patients with type 2 diabetes, a large retrospective cohort study suggested...
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