(MedPage Today) -- An FDA panel said that trial data did not provide substantial evidence showing that investigational deramiocel was effective in treating cardiomyopathy among patients with Duchenne muscular dystrophy.
In a 9-3 vote, the FDA...
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-
FDA Committee Votes Down Duchenne Drug
via medpagetoday.com -
Study on Vaginal Estrogen for UTI Prevention Backs a Less Messy Approach
via medpagetoday.com(MedPage Today) -- Periurethral application of a smaller amount of estradiol cream with a finger was noninferior to standard intravaginal application with an applicator among postmenopausal patients with recurrent urinary tract infections (UTIs... -
Senate Considers Vote to Hold Fauci in Contempt
via medpagetoday.com(MedPage Today) -- A Senate committee plans to vote next week on whether to recommend holding Anthony Fauci, MD, in contempt following a hearing on Wednesday that centered on how the infectious disease expert handled the COVID-19 pandemic as well... -
Sodium Channel Blocker Cuts Post-Surgery Pain
via medpagetoday.com(MedPage Today) -- The sodium channel blocker LTG-001, an investigational selective Nav1.8 inhibitor, reduced pain scores more than placebo for 2 days after abdominoplasty, a phase IIb trial showed.
The primary endpoint was the time-weighted sum... -
CAR T-Cell Therapy in Pregnant Autoimmune Patients: Safe for Baby?
via medpagetoday.com(MedPage Today) -- So far, pregnancies among the first women treated with chimeric antigen receptor (CAR) T-cell therapy for autoimmune rheumatologic diseases have proceeded without any concerns, researchers reported.
With 14 pregnancies occurring... -
Senate Dems Question if RFK Jr.'s Family Will Profit From Vax Settlement
via medpagetoday.com(MedPage Today) -- Four Democratic lawmakers have questioned whether HHS Secretary Robert F. Kennedy Jr.'s family will profit from a sizeable settlement involving Merck's human papillomavirus (HPV) vaccine (Gardasil).
In a letter dated July 28... -
FDA Licenses First Freeze-Dried Plasma Product
via medpagetoday.com(MedPage Today) -- The FDA licensed Ezplaz, the first freeze-dried plasma product available to adults in need of transfusion, on Wednesday.
Ezplaz is intended for patients who need plasma--such as those who are bleeding, need massive transfusion... -
CDC Suggests Threat of Mold-Associated Illnesses May Be Underappreciated
via medpagetoday.com(MedPage Today) -- A first-of-its-kind U.S. study suggests invasive mold infections may be an underappreciated--and potentially deadly--threat.
The researchers detected about 450 cases in Atlanta-area hospitals over 5 years. About a third... -
Sugar Rationing in Early Life Linked to Lower Dementia Risk Decades Later
via medpagetoday.com(MedPage Today) -- People who consumed less sugar in utero and before age 2 had a lower risk of developing dementia later in life, data from 65,000 U.K. Biobank participants suggested.
The study used the abrupt end of World War II sugar rationing... -
Surgery Underused for Primary Hyperparathyroidism With End-Organ Damage, Study Says
via medpagetoday.com(MedPage Today) -- Only a small fraction of patients with primary hyperparathyroidism (PHPT)-associated end-organ damage underwent surgical treatment, a large national cohort study found.
Among over 43,000 adults with biochemically diagnosed PHPT... -
Leadership Shakeup at CDC's Ebola Response Team
via medpagetoday.com(MedPage Today) -- Amid the ongoing Ebola outbreak in the Democratic Republic of Congo, the CDC has relieved the two top leaders of its Ebola response team of their positions.
Incident manager Satish Pillai, MD, MPH, and deputy incident manager... -
Florida Warns on Psych Meds in Kids; Binge Drinking While Pregnant; ADHD in Females
via medpagetoday.com(MedPage Today) -- Florida health officials released new guidance discouraging the use of psychiatric medications for children with anxiety, depression, attention deficit-hyperactivity disorder (ADHD), and behavioral disorders.
A twice-daily dose... -
The Double Standard in the Peptide Vote
via medpagetoday.com(MedPage Today) -- Before I write a prescription for chronic insomnia, I want to know what molecule I am handing the patient, at what dose, and on what basis. Those are ordinary requirements. Yet, last week, a federal advisory committee recommended... -
Precision Medicine Shows Promise for Pediatric Diffuse Hemispheric Glioma
via medpagetoday.com(MedPage Today) -- At the International Symposium on Pediatric Neuro-Oncology (ISPNO), it was reported that personalized treatment guided by deep molecular profiling produced encouraging survival outcomes in a subset of children with H3 G34-altered... -
Social care reform is a test of UK politics
via ft.comEfforts to fix England’s broken system must answer the question: who pays? -
Oz Declined Shot at HHS Top Job; Gene Editing Death; CDC Ordered Border Detentions
via medpagetoday.com(MedPage Today) -- CMS Administrator Mehmet Oz, MD, reportedly passed up an opportunity to step into the HHS Secretary's shoes amid a White House overhaul of the agency earlier this year. Here's how Oz gained the trust of the president, Robert... -
Uganda Declares Itself Free of Ebola as Congo Continues to Struggle
via medpagetoday.com(MedPage Today) -- Authorities in Uganda declared the East Africa nation free of Ebola on Tuesday following the discharge of the country's last patient in mid-June, a delicate milestone as the virus continues to plague neighboring Congo.
Uganda... -
Two Drugs Matched Three for Untreated HIV
via medpagetoday.com(MedPage Today) -- A two-drug regimen was noninferior to a three-drug regimen as initial antiretroviral therapy (ART) for adults with HIV, a phase IIIb trial showed.
At week 48, an HIV-1 RNA level of less than 50 copies/mL was achieved by 89... -
Fauci Invokes 5th Amendment; Medicare Subsidies to End; Blood Supply Crisis
via medpagetoday.com(MedPage Today) -- Note that some links may require registration or subscription.
Anthony Fauci, MD, on Wednesday invoked the 5th Amendment and declined to answer questions from senators in a Republican-led committee hearing about his handling... -
Burnham opens door to tax rises to pay for social care overhaul
via ft.comPrime minister says he wants to avoid people having to sell their homes to pay for care
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