Medical Industry news

• First Drug for Deadly Transplant Complication Gets FDA's Blessing

  24-12-2025 20:12 via medpagetoday.com
  (MedPage Today) -- The FDA has approved narsoplimab (Yartemlea) as the first treatment for hematopoietic stem cell transplant (HSCT)-associated thrombotic microangiopathy (TA-TMA) in adults and kids ages 2 years and up, said maker Omeros on Wednesday...
  
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• Nick Reiner's Schizophrenia Meds; Depression and Heart Risk; State Mental Hospitals

  24-12-2025 18:25 via medpagetoday.com
  (MedPage Today) -- Nick Reiner, who has schizophrenia, had his medications changed prior to the killings of his parents, according to sources familiar with the case. (NBC News)
  The FDA recommended Reviva Pharmaceuticals conduct another phase III...
  
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• FDA Approves Mitapivat for Thalassemia-Related Anemia

  24-12-2025 18:19 via medpagetoday.com
  (MedPage Today) -- The FDA approved mitapivat (Aqvesme) as a disease-modifying treatment for anemia in adults with alpha- or beta-thalassemia, a rare inherited blood disease that affects hemoglobin production.
  An oral pyruvate kinase (PK) activator...
  
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• 19 States Sue HHS Over Move to Curtail Youth Gender-Affirming Care

  24-12-2025 18:09 via medpagetoday.com
  (MedPage Today) -- A coalition of 19 states and the District of Columbia on Tuesday sued HHS, its secretary Robert F. Kennedy Jr., and its inspector general over a declaration that could complicate access to gender-affirming care for young people...
  
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• Incretin Therapies After Bariatric Surgery Linked to Lower Risk of Alcohol Disorder

  24-12-2025 17:49 via medpagetoday.com
  (MedPage Today) -- Treatment with incretin-based weight-loss medications, like GLP-1 receptor agonists, after bariatric surgery was associated with significantly lower risks of alcohol use disorder (AUD) and initiation of medications for AUD compared...
  
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• Psoriasis Advances That Could Change Daily Practice

  24-12-2025 17:24 via medpagetoday.com
  (MedPage Today) -- In the second half of his Maui Derm recap, George Martin, MD, founder and program director of the meeting, highlights new strategies on the horizon for psoriasis--from an interleukin (IL)-23 biologic dosed just once or twice...
  
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• Who's Really Running NIH? Kennedy Promotes CDC Contact; Toxic Airplane Fumes

  24-12-2025 16:44 via medpagetoday.com
  (MedPage Today) -- Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week.
  Who's Really in Charge at NIH?
  Inside the NIH, some have described director Jay Bhattacharya...
  
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• Statins Linked to IBD Benefit; Hormones and IBS; Quicker Hep C Cure Confirmation?

  24-12-2025 16:17 via medpagetoday.com
  (MedPage Today) -- Statin use in patients with moderate-to-severe inflammatory bowel disease (IBD) was associated with a 49% lower odds of IBD-related surgery, a retrospective study found. (Inflammatory Bowel Diseases)
  Meanwhile, tonsillectomy...
  
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• HPV Vaccine Protection Extends to High-Grade Vulvovaginal Precancers

  24-12-2025 16:03 via medpagetoday.com
  (MedPage Today) -- Women vaccinated against human papillomavirus (HPV) had a significantly lower risk of high-grade vulvovaginal lesions, a large cohort study from Sweden showed.
  Vaccinated women had a 37% lower risk of developing lesions, which...
  
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• Deck the Halls With Ow's From Folly: What the Numbers Tell Us About Holiday Injuries

  24-12-2025 16:00 via medpagetoday.com
  (MedPage Today) -- Jingle bells don't belong in the esophagus. Santa's lap isn't a safe zone for the fall-prone. And men might not want to try certain alternative sexual maneuvers after loading up on eggnog and pumpkin pie.
  These are just a few...
  
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• Outbreak Hospitalizes 20; Former Senator's 'Death Sentence'; World's Oldest Doc Dies

  24-12-2025 15:01 via medpagetoday.com
  (MedPage Today) -- Note that some links may require registration or subscription. Also note that MedPage Today will be closed Thursday and Friday in observance of the Christmas holiday. Look for Morning Break again on Monday, Dec. 29.
  Raw oysters...
  
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• The Ins and Outs of Respiratory Virus Vaccines for Immunocompromised Patients

  24-12-2025 15:00 via medpagetoday.com
  (MedPage Today) -- When it comes to questions about respiratory virus vaccination in immunocompromised children and adults, the answers may be clearer than many clinicians think, according to a panel of infectious disease experts.
  In a presentation...
  
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• U.S. Signs New Health Deals With 9 African Countries That Mirror Trump's Priorities

  23-12-2025 22:50 via medpagetoday.com
  (MedPage Today) -- The U.S. government has signed health deals with at least nine African countries, part of its new approach to global health funding, with agreements that reflect the Trump administration's interests and priorities and are geared...
  
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• Overcoming CDK4/6 Inhibitor Resistance in HR-Positive/HER2-Negative Breast Cancer

  23-12-2025 21:32 via medpagetoday.com
  (MedPage Today) -- In the decade since palbociclib (Ibrance) received FDA approval, results from multiple clinical trials have provided a strong evidence base to make cyclin-dependent kinase (CDK)4/6 inhibitors, in combination with endocrine therapy...
  
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• Alzheimer's Paper Retracted; Lipoic Acid and MS; Botched Autism Drug Rollout

  23-12-2025 20:26 via medpagetoday.com
  (MedPage Today) -- Science Signaling retracted a 2017 paper that linked a specific amyloid form (amyloid-beta 56) to tau pathology after an investigation into allegations of data manipulation. Author Sylvain Lesné, PhD, who resigned from the...
  
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• Assessing Non-Glandular Manifestations of Sjogren's Disease

  23-12-2025 19:19 via medpagetoday.com
  (MedPage Today) -- Beyond sicca symptoms, Sjögren's disease can involve non-glandular manifestations such as dysautonomia and small fiber neuropathy that are often difficult to assess and manage. At this year's American College of Rheumatology...
  
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• Prediabetes Reversal Benefits; Many Seniors Quit GLP-1s in a Year; Testosterone Fads

  23-12-2025 19:07 via medpagetoday.com
  (MedPage Today) -- Achieving prediabetes remission was tied to a decades-long benefit--a reduction in risk of cardiovascular death or hospitalization for heart failure--in a post-hoc analysis of two landmark diabetes prevention trials...
  
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• The Midterms Are Coming. Vaccines May Play a Role.

  23-12-2025 18:58 via medpagetoday.com
  (MedPage Today) -- Restricting access to vaccines and discouraging the development of new vaccines are grave public policy and public health mistakes. This will eventually have a catastrophic impact on children's health, be a major hit to workplace...
  
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• Long-Term Tofersen Use May Slow ALS Progression, 3-Year Data Suggest

  23-12-2025 18:46 via medpagetoday.com
  (MedPage Today) -- Early initiation of tofersen (Qalsody) was associated with a numerically slower decline in people with SOD1 amyotrophic lateral sclerosis (ALS) compared with delayed treatment, according to data from the VALOR trial and its open...
  
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• 'Armored' CAR T Cells Show Early Promise in Relapsed B-Cell ALL

  23-12-2025 18:16 via medpagetoday.com
  (MedPage Today) -- At the recent American Society of Hematology annual meeting, phase I data highlighted a next-generation, CD19-targeted, interleukin-18-secreting "armored" CAR T-cell therapy that is designed to enhance persistence and antileukemic...
  
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• FDA Approves First Oral Medication for Iron Deficiency in Kids

  23-12-2025 18:02 via medpagetoday.com
  (MedPage Today) -- The FDA has expanded the indication of ferric maltol (Accrufer) capsules for the treatment of iron deficiency to include adolescents.
  The approval makes the drug the first prescription oral medicine for iron deficiency in pediatric...
  
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• Blood-Based Immune Markers May Predict Response to Preoperative Therapy in TNBC

  23-12-2025 17:27 via medpagetoday.com
  (MedPage Today) -- At the San Antonio Breast Cancer Symposium, investigators reported findings from a retrospective study exploring whether routine blood-based immune markers could help predict response to neoadjuvant chemoimmunotherapy in early...
  
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• Reassuring Findings for Use of Common Sleep Medications in Pregnancy

  23-12-2025 17:14 via medpagetoday.com
  (MedPage Today) -- Exposure to nonbenzodiazepine sedative hypnotics, known as Z-drugs, in the first trimester of pregnancy was not associated with an increased risk of congenital malformations, a population-based cohort study suggested.
  Among...
  
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• Medicaid Paid More Than $207 Million for Dead People. A New Law Could Help Fix That.

  23-12-2025 16:40 via medpagetoday.com
  (MedPage Today) -- Medicaid programs made more than $200 million in improper payments to healthcare providers between 2021 and 2022 for people who had already died, according to a new report from the independent watchdog for the Department of Health...
  
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• The Promise of Biomarkers to Direct Chronic Spontaneous Urticaria Therapy

  23-12-2025 15:30 via medpagetoday.com
  (MedPage Today) -- Pathophysiologic biomarkers for chronic spontaneous urticaria (CSU) are emerging, which can help better target therapies for the potentially debilitating condition.
  Heterogeneity in CSU--characterized by spontaneous occurrence...
  
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• FDA Approves Wegovy Weight-Loss Pill

  23-12-2025 15:25 via medpagetoday.com
  (MedPage Today) -- The FDA approved a pill version of the GLP-1 receptor agonist semaglutide (Wegovy), making it the first oral GLP-1 agent indicated for weight loss, Novo Nordisk announced on Monday.
  The once-daily 25 mg pill is approved to lower...
  
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• Can You Pass a Health Scam Quiz? Trial Death Reported; Views on MMR Vax Slide

  23-12-2025 15:10 via medpagetoday.com
  (MedPage Today) -- Note that some links may require registration or subscription.
  Amid a heightened volume of health scams, this quiz may help determine your risk of falling for one. (New York Times)
  Pfizer said a patient in a trial of its hemophilia...
  
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• FcRn Blockers Vie to Become First Approved Drug for Sjogren's Disease

  23-12-2025 14:49 via medpagetoday.com
  (MedPage Today) -- The first FDA-approved treatment option for Sjögren's disease might be on the horizon, as neonatal Fc receptor (FcRn) blockers show promise in early data.
  B-cell activation in Sjögren's disease results in immunoglobulin...
  
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• Here's Where Measles Case Counts Are Highest

  23-12-2025 14:30 via medpagetoday.com
  (MedPage Today) -- Map highlights total U.S. cases in 2025 and past-week increases
  
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• Once-Weekly Oral Combo for HIV Maintains High Rates of Virologic Suppression

  22-12-2025 23:42 via medpagetoday.com
  (MedPage Today) -- A once-weekly oral combination of islatravir plus lenacapavir (Sunlenca) for HIV maintained similarly high rates of virologic suppression compared with standard daily oral treatment in an open-label phase II trial.
  In 104 virologically...
  
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• I've Survived Two School Shootings. I Implore You to Speak Up.

  22-12-2025 23:12 via medpagetoday.com
  (MedPage Today) -- If you've read the news recently, chances are you have seen the headlines about the mass shooting at Brown University that killed two of my fellow Brown students and injured nine others. You might have also seen me on the news...
  
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• More Americans Experience Troublesome Healthcare Costs Than Previously Thought

  22-12-2025 23:03 via medpagetoday.com
  (MedPage Today) -- A greater share of Americans than previously suggested experience burdensome healthcare costs, according to results from a nationally representative cohort study.
  Among more than 12,600 survey participants, 6.5% said they experienced...
  
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• Air Pollution Linked to Depression

  22-12-2025 22:07 via medpagetoday.com
  (MedPage Today) -- Long-term exposure to pollution from fine particulate matter and its major components--soil dust, sulfate, and elemental carbon--correlated with a greater risk of depression among older adults, a U.S. study showed.
  In...
  
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• Nirsevimab Might Top Maternal Vax for Infants' RSV Protection

  22-12-2025 21:50 via medpagetoday.com
  (MedPage Today) -- Infants given the monoclonal antibody nirsevimab (Beyfortus) to provide passive immunity against respiratory syncytial virus (RSV) had a lower rate of related hospitalizations and severe outcomes than those whose mothers got...
  
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• Benzodiazepines Linked With Adverse Pregnancy Outcomes

  22-12-2025 21:25 via medpagetoday.com
  (MedPage Today) -- Use of benzodiazepines during pregnancy, particularly in the second trimester, was linked to some adverse pregnancy outcomes, a Taiwanese cohort study found.
  Among 454,477 pregnancies, benzodiazepine use was associated with...
  
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• FDA Opens Door to Quicker Approval of Osteoporosis Drugs

  22-12-2025 21:19 via medpagetoday.com
  (MedPage Today) -- The FDA gave the greenlight to use total hip bone mineral density (BMD) as a validated surrogate endpoint for clinical osteoporosis drug trials, the FDA announced on Friday.
  A BMD test measures calcium and other bone minerals...
  
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• CMS Funds 400 New Residency Slots

  22-12-2025 21:07 via medpagetoday.com
  (MedPage Today) -- The decision to fund 400 new medical residency positions at hospitals across the U.S. marks a meaningful--though limited--step toward addressing a looming physician shortage expected to worsen over the next decade, public...
  
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• Half of Transgender, Gender Diverse Youth Report Suicidal Thoughts

  22-12-2025 20:55 via medpagetoday.com
  (MedPage Today) -- Nearly one in two transgender and gender diverse (TGD) youth reported suicidal ideation or self-injury, and one in four attempted suicide, a global meta-analysis showed.
  In a study of 131,429 TGD individuals ages 25 and younger...
  
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• Twins Joined at the Heart: Single Embryo Transfer Results in Unusual Case

  22-12-2025 19:17 via medpagetoday.com
  (MedPage Today) -- When a woman in her mid-40s underwent a single, genetically normal embryo transfer, clinicians expected--and counseled for--a singleton pregnancy.
  What followed instead was one of the rarest outcomes in assisted reproduction...
  
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• Study: Keep Hydroxychloroquine Doses High in Lupus

  22-12-2025 19:13 via medpagetoday.com
  (MedPage Today) -- Hydroxychloroquine (HCQ) doses of at least 400 mg/day provided better symptom relief for Taiwanese people with systemic lupus erythematosus (SLE) compared with lower doses, with the added benefit of less risk for cardiovascular...
  
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• Adding Tucatinib in First-Line Maintenance Boosts PFS in HER2-Positive Breast Cancer

  22-12-2025 18:56 via medpagetoday.com
  (MedPage Today) -- At the San Antonio Breast Cancer Symposium, investigators presented results from HER2CLIMB-05, a registrational trial evaluating the addition of tucatinib (Tukysa) to trastuzumab (Herceptin) and pertuzumab (Perjeta) maintenance...
  
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• Next-Gen Oral SERD Cuts Recurrence Risk in Early Breast Cancer

  22-12-2025 18:28 via medpagetoday.com
  (MedPage Today) -- At the San Antonio Breast Cancer Symposium, investigators reported phase III results showing that the oral selective estrogen-receptor degrader (SERD) giredestrant significantly reduced recurrence risk compared with standard...
  
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• Bispecific Antibody Effective in Untreated Follicular Lymphoma

  22-12-2025 18:08 via medpagetoday.com
  (MedPage Today) -- At the recent American Society of Hematology (ASH) annual meeting, phase II data were presented on a bispecific antibody for patients with previously untreated follicular lymphoma with a high tumor burden.
  In this MedPage Today...
  
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• New Drug Approved for Hypertrophic Cardiomyopathy

  22-12-2025 18:06 via medpagetoday.com
  (MedPage Today) -- The FDA on Friday approved aficamten (Myqorzo) for symptomatic obstructive hypertrophic cardiomyopathy (HCM), drugmaker Cytokinetics announced.
  Aficamten is an allosteric and reversible inhibitor of cardiac myosin motor activity...
  
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• Trump Announces Lower Drug Price Deals With 9 Pharmaceutical Companies

  22-12-2025 17:20 via medpagetoday.com
  (MedPage Today) -- President Trump announced on Friday that nine drugmakers have agreed to lower the cost of their prescription drugs in the U.S.
  Pharmaceutical companies Amgen, Bristol Myers Squibb, Boehringer Ingelheim, Genentech, Gilead Sciences...
  
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• Polatuzumab-Based Combination Continues to Impress in Real-World DLBCL Analyses

  22-12-2025 16:55 via medpagetoday.com
  (MedPage Today) -- At the recent American Society of Hematology annual meeting, real-world analyses examined how polatuzumab vedotin (Polivy) with rituximab, cyclophosphamide, doxorubicin, and prednisone (pola-R-CHP) is being adopted outside of...
  
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• Sniffing Out the Optimal Radiation Dose for Head and Neck Cancer

  22-12-2025 16:44 via medpagetoday.com
  (MedPage Today) -- Sense of smell in patients with head and neck cancer began to deteriorate at a radiation dose of 22 Gy and increased in a dose-related fashion, a small prospective study showed.
  Fewer than 20% of the 63 patients developed noticeable...
  
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• Fellow Nurses: Did You (or Will You) Go to Your Staff Christmas Party?

  22-12-2025 16:20 via medpagetoday.com
  (MedPage Today) -- It's the time of year again to deck the halls and get on your jingle jolly way, and with my holiday party date fast approaching I wondered--as I do every year--should I go? Did I really want to hang out with my coworkers...
  
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• Cheddar Cheese Recalled; Nick Reiner's Medication Change; How Safe Is U.S. Food?

  22-12-2025 15:28 via medpagetoday.com
  (MedPage Today) -- Note that some links may require registration or subscription.
  Some cheddar cheese products branded as Charlevoix Cheese Company Farm have been recalled due to potential Listeria contamination.
  Flu activity is high or very...
  
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• 'Parents Are Going to Be Very Scared for No Reason': What We Heard This Week

  21-12-2025 22:00 via medpagetoday.com
  (MedPage Today) -- "Parents are going to be very scared for no reason to get the COVID-19 vaccine."--Flor Munoz-Rivas, MD, of the Baylor College of Medicine in Houston, commenting on confusing federal vaccine recommendations in light of a new...
  
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