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-
Giant craters in Canada's melting permafrost impacting climate change: researchers
via cbc.caResearchers are investigating large craters of melting permafrost in northern Canada, which they say are both a consequence of climate change and a contributing factor. -
Google wants to bring augmented reality to '100 million' devices this winter
via cbc.caAll you'll need is a recent Android smartphone — no specialized hardware required. -
Whale gets entangled in cruise ship anchor for hours in southeast Alaska
via cbc.caA humpback whale became entangled in an anchor line on a small cruise ship in southeast Alaska, getting stuck for roughly 12 hours while federal authorities and the boat's crew worked to free it. -
How gut bacteria may affect anxiety
Microbes may tamper with the production of tiny molecules in brain regions that help control anxiety. -
Warming oceans may cause the world's fish to shrink, study suggests
via cbc.caAs climate change continues to warm the world's oceans, a new study suggests the fish that inhabit them may, in response, shrink in size as much as 30 per cent in the next 30 years. -
CRTC orders wholesale high speed access for small ISPs in Ontario and Quebec
via cbc.caThe CRTC is mandating that Canada's big telecom companies give smaller internet providers access to their wholesale high-speed services over fibre-optic networks, first in Quebec and Ontario, before rolling out across the rest of the country. -
Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling
Cytoskeletal reorganization in osteoclasts to form actin rings is necessary for these cells to attach to bone and resorb bone matrices. We delineated the pathway through which Wnt5a signaling through receptor tyrosine kinase–like orphan receptor 2 (Ror2) promoted the bone-resorbing activity of osteoclasts. Wnt5a binding to Ror2 stimulated Rho, a small GTPase involved in cytoskeletal reorganization. Subsequently, the Rho effector kinase Pkn3 bound to and enhanced the activity of c-Src, a no -
Papers of note in Science Translational Medicine 9 (404)
This week’s articles describe potential therapeutic strategies to reduce hydrocephaly in infants, to kill liver cancer cells, and to improve MeCP2-associated neurological disorders. -
Papers of note in Science 357 (6353)
This week’s articles describe the signals mediating gut microbe activation of T cells, skin patterning in development, and photosynthesis. -
Papers of note in Nature 548 (7668)
This week’s articles describe how the stroma promotes tissue regeneration in the stomach; show how mitosis, the DNA sensor cGAS, and CDK inhibitors contribute to antitumor immunity; and describe the mechanism of action of an allosteric beta blocker. -
Blockade of surface-bound TGF-{beta} on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment
Regulatory T cells (Tregs) suppress antitumor immunity by inhibiting the killing of tumor cells by antigen-specific CD8+ T cells. To better understand the mechanisms involved, we used ex vivo three-dimensional collagen-fibrin gel cultures of dissociated B16 melanoma tumors. This system recapitulated the in vivo suppression of antimelanoma immunity, rendering the dissociated tumor cells resistant to killing by cocultured activated, antigen-specific T cells. Immunosuppression was not observed when -
An epigenetic tactic to treat RMS
BET inhibitors may be an effective treatment for some rhabdomyosarcomas. -
Activation of master virulence regulator PhoP in acidic pH requires the Salmonella-specific protein UgtL
Acidic conditions, such as those inside phagosomes, stimulate the intracellular pathogen Salmonella enterica to activate virulence genes. The sensor PhoQ responds to a mildly acidic pH by phosphorylating, and thereby activating, the virulence regulator PhoP. This PhoP/PhoQ two-component system is conserved in a subset of Gram-negative bacteria. PhoQ is thought to be sufficient to activate PhoP in mildly acidic pH. However, we found that the Salmonella-specific protein UgtL, which was horizontall -
Ship that sank in Cambridge Bay 87 years ago finally on journey home to Norway
via cbc.caIt’s a milestone seven years in the making: 87 years since the Maud sank near Cambridge Bay, Nunavut, the vessel is finally on its journey home. -
Uber will stop tracking customers after ride is over
via cbc.caUber Technologies Inc. is pulling a heavily criticized feature from its app that allowed it to track riders for up to five minutes after a trip, its security chief told Reuters, as the ride-hailing company tries to fix its poor reputation for customer privacy. -
Mothers master tricky timing to give babies a boost, squirrel study suggests
via cbc.caSome squirrels mate like rabbits during seasons of abundance — bolstering the survival rates of their young, a new study from the University of Alberta suggests. -
How science has fed stereotypes about women
A new book, Inferior, shows how biased research branded women as inferior and aims to set the record straight. -
Smelly clue to bird navigation skills
via bbc.co.ukBirds rely on smell to find their bearings when land is out of sight, according to a study. -
Mark Zuckerberg and family welcome new baby
via cbc.caFacebook CEO Mark Zuckerberg and his wife are welcoming a new baby, another daughter. -
Domino's tests pizza delivery by self-driving cars
via cbc.caDomino's and Ford are teaming up to see if customers will warm to the idea of pizza delivered by driverless cars. Bonus: You don't need to tip the driver. -
James Webb Space Telescope Surrounded by Rising Floodwaters
via rss.sciam.comIsolated in a giant thermal vacuum chamber, NASA’s $8.6 billion next-generation observatory is riding out the worst of Hurricane Harvey
-- Read more on ScientificAmerican.com -
Bones reveal what it was like to grow up dodo
Scientists take a first look at the inside of dodo bones. -
Newfound Material on the Moon Could Offer Clues to Our Planet's Early Years
via rss.sciam.comA spacecraft has uncovered in lunar soil some traces of Earth’s ancient atmosphere that werekey to the development of complex life
-- Read more on ScientificAmerican.com -
Endangered P.E.I. plovers saved by pizza pan
via cbc.caA plover nest was saved from being washed out when Parks Canada staff used a pizza pan to scoop the area of sand further up on the beach. -
Canada's electronic spy agency to get new rules for sharing data with allies
via cbc.caThe office of Defence Minister Harjit Sajjan is crafting a directive for how Canada’s electronic spy agency shares its foreign signals intelligence with its closest allies, the Five Eyes partners. -
Look at the stars: Gros Morne gunning for dark sky designation
via cbc.caGros Morne could soon be joining nine other national parks across Canada in getting a special designation to help with stargazing and astronomy. -
Lummi Nation fishermen catch an estimated 20,000 Atlantic salmon following fish farm collapse
via cbc.caIt's unclear how many Atlantic salmon escaped from the pen. The Lummi Nation says tribal fishermen have removed 20,000 from the Puget Sound. Washington state officials says Cooke Aquaculture has recovered 120,000 fish from the pen and that more are still inside. -
Why does rubbing a balloon on your hair make it stick?
(Case Western Reserve University) New research led by Case Western Reserve University indicates that tiny holes and cracks in a material -- changes in the microstructure -- can control how the material becomes electrically charged through friction. -
Where's the line? Managing extreme speech on social media
(University of Missouri-Columbia) A new study from the University of Missouri School of Journalism shows that while people tend to dislike extreme speech on social media, there is less support for outright censorship. Instead, people believe sites need to do a better job promoting healthy discourse online. -
When it comes to antennas, size matters
(Northeastern University) In a paper published online in Nature Communications, Nian Sun, professor of electrical and computer engineering at Northeastern, and his colleagues describe a new approach to designing antennas. The discovery enables researchers to construct antennas that are up to a thousand times smaller than currently available antennas, Sun said. -
Weightlessness affects health of cosmonauts at molecular level
(Moscow Institute of Physics and Technology) It is widely known that space conditions influence metabolism, thermoregulation, heart biorhythms, muscle tone and other physiological aspects. However, the molecular mechanisms which drive the physiological changes caused by space flights remain unknown.Scientists analyzed the effect of space conditions on the protein composition in blood samples of 18 Russian cosmonauts. The results indicated many significant changes in the human body caused by spac -
The eyes have it
(University of California - Santa Barbara) Postdoctoral Fellow Georgina Stooke-Vaughan investigates the mechanical development of the eye. -
Tears in tiny bone cells called osteocytes appear an important step to better bones
(Medical College of Georgia at Augusta University) The force gravity and physical activity put on our bones causes tiny tears in the membranes of the tiny cells that enable us to make or break down bone, scientists say.While that may sound bad, it's actually a key piece of how the force we put on our bones helps keep them strong, they report in the Journal of Orthopaedic Research. -
Researchers validate UV light's use in improving semiconductors
(DOE/National Renewable Energy Laboratory) A discovery by two scientists at the Energy Department's National Renewable Energy Laboratory could aid the development of next-generation semiconductor devices. -
Recipients of George Michael Memorial High Performance Computing Fellowships announced
(Association for Computing Machinery) The Association for Computing Machinery and the IEEE Computer Society jointly announced today that Shaden Smith of the University of Minnesota and Yang You of the University of California, Berkeley, are the recipients of the 2017 ACM/IEEE-CS George Michael Memorial HPC Fellowships. -
Preventing sudden death in hypertrophic cardiomyopathy: ESC guidelines (HCM-EVIDENCE)
(European Society of Cardiology) A large study conducted across North America, Europe, the Middle East and Asia has validated the ESC recommendations for predicting and preventing sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM). -
Potential Tropical Cyclone 10 soaks Mid-Atlantic
(NASA/Goddard Space Flight Center) NOAA's GOES East satellite provided an image of Potential Tropical Cyclone 10 as it continued moving north along the US East Coast. -
Placenta-on-a-chip: Microsensor simulates malaria in the womb to develop treatments
(Florida Atlantic University) By combining microbiology with engineering technologies, researchers from Florida Atlantic University are developing a first-of-its-kind 3-D model that uses a single microfluidic sensing chip to study the complicated processes that take place in malaria-infected placenta as well as other placenta-related diseases and pathologies. The chip will mimic the microenvironment of placental malaria, specifically the maternal-fetal interface. -
Pinpointing the origins of autism
(McGill University) The origins of autism remain mysterious. What areas of the brain are involved, and when do the first signs appear? New findings published in Biological Psychiatry brings us closer to understanding the pathology of autism, and the point at which it begins to take shape in the human brain. Such knowledge will allow earlier interventions in the future and better outcomes for autistic children. -
Obesity prevention guidelines are not followed for preschool children
(Cincinnati Children's Hospital Medical Center) In a study of nearly 400 preschool children, only one child adhered to obesity prevention guidelines over the course of a single day at child care and at home. -
Obese people lack cells with satiety hormones
(University of Basel) Individuals with severe overweight have an inhibited sense of satiation -- they release fewer satiety hormones than people of normal weight. The reason: the responsible cells in the gastrointestinal tract of obese people are severely reduced. This report by Swiss doctors is in the journal Scientific Reports. Surgical weight-loss procedures can repair this disorder. -
NTU scientists use brewery waste to grow yeast needed for beer making
(Nanyang Technological University) Scientists from Nanyang Technological University, Singapore (NTU Singapore) have invented a new process to turn spent brewery grains into a valuable product that can grow beer yeast. -
NSF grant will study Kansans' inequality of broadband access
(University of Kansas) University of Kansas researchers have received a $300,000 National Science Foundation grant to study digital inequalities in Kansas and begin designing a set of cybersecurity and privacy tools to protect public broadband users. -
NREL updates baseline cost and performance data for electricity generation technologies
(DOE/National Renewable Energy Laboratory) The Energy Department's National Renewable Energy Laboratory has released the 2017 Annual Technology Baseline (ATB), updating a key source of reliable electricity generation technology cost and performance data used to support and inform electric sector analysis in the United States. Now in its third year, the ATB documents technology-specific information on a broad spectrum of electricity generation technologies, including wind, solar, geothermal, hydr -
NREL, Swiss scientists power past solar efficiency records
(DOE/National Renewable Energy Laboratory) Collaboration between researchers at the US Department of Energy's National Renewable Energy Laboratory, the Swiss Center for Electronics and Microtechnology, and the École Polytechnique Fédérale de Lausanne shows the high potential of silicon-based multijunction solar cells. -
NREL analysis identifies where commercial customers might benefit from energy storage
(DOE/National Renewable Energy Laboratory) Commercial electricity customers who are subject to high demand charges may be able to reduce overall costs by using battery energy storage to manage demand, according to research by the US Department of Energy's National Renewable Energy Laboratory. -
Non-thermal atmospheric pressure plasma treatment
(Bentham Science Publishers) India is a second largest producer of leather, and being so, leather production and dyeing significantly contribute to pollution of water resources in India. Consistent dyeing of leather is difficult due to the unique nature of the raw material (matrix of collagen fibers), thus leather dyeing and finishing involves numerous wet chemical treatments having huge environmental impacts. -
New research strengthens link between mental health and retirement savings
(Medica Research Institute) The question of how mental health status affects decisions regarding retirement savings is becoming a pressing issue in the United States. Key factors contributing to this issue include the tenuous state of the Social Security system, greater use of defined-contribution pension plans by employers, longer lifespans, and the rise of depression and other mental health issues in older Americans. -
New mini tool has massive implications
(Brigham Young University) Researchers have created a miniaturized, portable version of a tool now capable of analyzing Mars' atmosphere -- and that's just one of its myriad possible uses. -
NASA's Lunar mission captures solar eclipse as seen from the moon
(NASA/Goddard Space Flight Center) LRO captured an image of the Moon's shadow over a large region of the United States, centered just north of Nashville, Tennessee.
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