Science news

• [Review] Revisiting protein kinase-substrate interactions: Toward therapeutic development

  22-03-2016 23:50 via stke.sciencemag.org
  Identifying conformational interactions between kinases and their substrates may improve the development and clinical success of kinase inhibitors.
  
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• [Research Article] A peptide of the RGS domain of GRK2 binds and inhibits Gaq to suppress pathological cardiac hypertrophy and dysfunction

  22-03-2016 23:50 via stke.sciencemag.org
  A GRK2-derived peptide inhibits pathological cardiac hypertrophy and may prevent heart failure.
  
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• [Research Article] A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals

  22-03-2016 23:50 via stke.sciencemag.org
  Recruitment of intracellular vesicles containing the large GTPase CRACR2A to the immunological synapse mediates T cell receptor signaling.
  
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• [Podcast] Science Signaling Podcast for 22 March 2016: Preventing heart failure with GRK2

  22-03-2016 23:50 via stke.sciencemag.org
  A GRK2-derived peptide reduces pathological cardiac hypertrophy in mice.
  
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• [Editors' Choice] SOX to be fat

  22-03-2016 23:50 via stke.sciencemag.org
  Increased abundance of the transcription factor SOX6 may contribute to the tendency of low-birthweight neonates to develop obesity later in life.
  
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• [Editors' Choice] New connections: Understanding GRK2 signaling to treat disease

  22-03-2016 23:50 via stke.sciencemag.org
  Understanding the effects of GRK2 signaling in vitro, in cells, and in organisms could result in novel therapeutic strategies.
  
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• [Editors' Choice] LIGHTing up the tumor microenvironment

  22-03-2016 23:50 via stke.sciencemag.org
  Two new ways of targeting immune cells may help kill cancer.
  
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• [Editors' Choice] IGF-1 modulates neuronal function

  22-03-2016 23:50 via stke.sciencemag.org
  Insulin-like growth factor 1 mediates changes in neuronal circuitry induced by sensory experience.
  
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• [Editors' Choice] A food clock in the VMH

  22-03-2016 23:50 via stke.sciencemag.org
  A circadian clock in the ventromedial hypothalamus controlled by light and nutrients regulates brown adipose metabolism.
  
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• 'So You Say There's a Chance': Yuri's Night Offers Patch for Astronaut Applicants

  22-03-2016 23:31
  
  So many people applied — almost three times as many as NASA's earlier record — that Yuri's Night, the world space party that celebrates the past, present and future of human spaceflight, thinks that it merits a badge of honor, literally. On Tuesday (March 22), Yuri's Night began selling the new "#BeAnAstronaut patch,"commemorating the tremendous turnout for the 2017 NASA astronaut recruitment. "It's a way to celebrate the record-breaking response to the next astronaut-selection proce
  
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• China says Philippines fishermen used fire bombs in South China Sea

  22-03-2016 22:30
  Philippines fishermen threw fire bombs at Chinese law enforcement vessels in the South China Sea, China's Foreign Ministry said on Tuesday, after Philippines media reported that fishermen had been struck by bottles hurled from China's coast guard ships. The reports said that a clash occurred at Scarborough Shoal, an area China seized control of after a three-month stand-off with the Philippine coast guard in 2012.
  
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• Liberals keep most of their green election promises in 1st budget

  22-03-2016 22:26 via cbc.ca
  
  The Liberal government will spend $5 billion over the next five years on greening Canada's infrastructure and another $1.75 billion over the next two years toward developing a clean economy and protecting the environment.
  
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• Brain holds more than one road to fear

  22-03-2016 22:00
  
  A study on rare patients suggests that fear can take many paths through the brain.
  
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• New 3D View of Richard III's Humble Grave Revealed

  22-03-2016 21:03
  
  Richard III's lost skeleton was discovered under a parking lot in Leicester in 2012. In honor of this one-year anniversary, the University of Leicester has released a digital 3D model of Richard III's original grave.
  
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• Congo president set for re-election, early results show

  22-03-2016 20:54
  By Roch Bouka BRAZZAVILLE (Reuters) - Congo Republic's President Denis Sassou Nguesso was on course on Tuesday to extend his long rule, according to preliminary election results that the opposition dismissed as fraudulent as police and troops patrolled the capital's streets. Election commission president Henri Bouka told reporters that Sassou Nguesso, who has ruled Congo for 32 of the last 37 years, won 67 percent of the vote in Sunday's election based on results from 72 of 111 voting districts.
  
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• U.S. offers $100,000 for info leading to Syrian Electronic Army hacking arrests

  22-03-2016 20:11 via cbc.ca
  
  Three current or former members of the so-called Syrian Electronic Army have been charged with computer hacking-related conspiracies that targeted the U.S. government, media and private-sector companies, the Justice Department announced Wednesday.
  
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• 3 accused Syrian Electronic Army hackers face U.S. charges

  22-03-2016 20:11 via cbc.ca
  
  Three current or former members of the so-called Syrian Electronic Army have been charged with computer hacking-related conspiracies that targeted the U.S. government, media and private-sector companies, the Justice Department announced Wednesday.
  
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• First Retailer in Orbit: Lowe's and Made In Space Send 3D Printer to Station

  22-03-2016 20:02
  
  Outer space is about to get its first pop-up retail shop. Lowe's, the home-improvement store, has teamed up with Made In Space, the company behind the world's first zero-G 3D printer, to launch the first commercial manufacturing facility on the International Space Station. The Additive Manufacturing Facility (AMF), as it is called, is an advanced, permanent 3D printer that will be available for use not only by NASA and its station partners, but also by researchers, educational organizations
  
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• Meteor-Tracking Experiment Headed to Space After 2 Failed Launches

  22-03-2016 19:46
  
  After two explosive setbacks, a meteor experiment designed to track "shooting stars" from space is again poised to launch to the International Space Station — and scientists are hoping the third time's the charm. Michael Fortenberry, principal investigator on the mission, called Meteor Composition Determination (Meteor for short), and a researcher at Southwest Research Institute in San Antonio, is eager to finally turn the tool's high-resolution camera toward the many meteor showers that r
  
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• First Space Shuttle Astronauts to Celebrate Flights' 35th Anniversaries

  22-03-2016 19:46
  
  Thirty-five years after they launched on board the "world's greatest all-electric flying machine," the astronauts who flew aboard NASA's first two space shuttle missions are set to land in Houston this September for an anniversary celebration. STS-1 pilot Robert Crippen, STS-2 commander Joe Engle and STS-2 pilot Richard Truly, who with Engle proved that the space shuttle was reusable, will be the honored guests at a dinner on Sept. 17 at Space Center Houston in Texas, the Astronaut Scholars
  
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• Meditation may be able to calm your chronic back pain as well as your mind

  22-03-2016 19:31
  
  Researchers found that training the brain to respond differently to pain signals could be more effective than traditional pain relief.
  
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• Congo's Sassou Nguesso leading in presidential poll

  22-03-2016 19:12
  By Roch Bouka BRAZZAVILLE (Reuters) - Congo Republic's President Denis Sassou Nguesso held a clear lead in Sunday's election to extend his long rule, preliminary results showed on Tuesday, as an internet and phone blackout was extended into a third day. Election commission president Henri Bouka told reporters that Sassou Nguesso, who has ruled Congo for 32 of the last 37 years, had won 67 percent of the vote in Sunday's election based on results from 72 of 111 voting districts. Former minister G
  
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• Space Fire! Special Experiment Launching on Cygnus Cargo Spacecraft

  22-03-2016 18:49
  
  The robotic Cygnus cargo spacecraft is scheduled to launch toward the International Space Station (ISS) tonight (March 22) atop a United Launch Alliance Atlas V rocket from Florida's Cape Canaveral Air Force Station at 11:05 p.m. EDT (0305 GMT on March 23). Cygnus is packed with nearly 4 tons of supplies and scientific hardware, most of which will be offloaded by astronauts after the freighter arrives at the orbiting lab this weekend.
  
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• Beetle's chemical signal tells mate, 'Honey, I'm not in the mood'

  22-03-2016 18:47
  
  WASHINGTON (Reuters) - When a female "burying beetle" is focused on caring for babies and not making new ones, she releases a chemical signal to her libidinous mate that says in no uncertain terms, "Honey, I'm not in the mood."
  
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• Physicists Unleash AI to Devise Unthinkable Experiments

  22-03-2016 18:45 via rss.sciam.com
  
  Researchers trying to divine the bizarre nature of quantum particle behavior are getting some help from software that designs counterintuitive experiments
  -- Read more on ScientificAmerican.com
  
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• Female burying beetle uses chemical cue to douse love life

  22-03-2016 17:00
  
  While raising their young, burying beetle mothers produce a chemical compound that limits their male partner’s desire to mate.
  
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• High Anxiety Risk in Adolescence Linked to One Gene

  22-03-2016 15:54
  Anxiety disorders often emerge in adolescence, when the brain goes through massive changes and new genes are expressed. Now, researchers have found a gene that may be a factor in the general peak of anxiety during this time. They also found that carrying a common version of this gene may protect people from anxiety.
  
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• New Patch Analyzes Sweat to Detect Blood Sugar Levels

  22-03-2016 15:53
  A stick-on patch that tracks, and even regulates, blood sugar levels could be used by people with diabetes one day, according to a new study. Unlike finger pricking — the traditional method of monitoring levels of the blood sugar glucose — the new patch detects the levels of glucose in a person's sweat. Research has shown that glucose levels in sweat accurately reflect glucose levels in the blood, the researchers said.
  
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• CO2 is flooding atmosphere at highest rate since Age of Dinosaurs

  22-03-2016 15:51 via cbc.ca
  
  The rate of carbon emissions is higher than at any time in fossil records stretching back 66 million years to the age of the dinosaurs, according to a study that sounds an alarm about risks to nature from man-made global warming.
  
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• Bedford student's water purification system wins spot at international science fair

  22-03-2016 15:47 via cbc.ca
  
  A 14-year-old Bedford student, inspired by Malala Yousafzai to create a water purification system, has landed a coveted spot at the Intel International Science and Engineering Fair.
  
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• Facebook to end support for BlackBerry app

  22-03-2016 15:39 via cbc.ca
  
  BlackBerry said it is "extremely disappointed" that the BlackBerry version of the Facebook app will no longer be supported.
  
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• Modern Peanut's Wild Cousin, Thought Extinct, Found in Andes

  22-03-2016 15:00 via rss.sciam.com
  
  A new study reveals how two ancient species of this legume were combined 10,000 years ago, in Andean valleys, to create the modern peanut
  -- Read more on ScientificAmerican.com
  
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• Private Cygnus Cargo Ship Launches to Space Station Tonight: Watch It Live

  22-03-2016 14:18
  
  An Orbital ATK Cygnus spacecraft is scheduled to launch toward the International Space Station tonight (March 22), and you can watch the liftoff live online. The robotic cargo spacecraft is set to launch atop a United Launch Alliance Atlas V rocket from Cape Canaveral's Launch Complex 41 at 11:05 p.m. EDT (0305 GMT on March 23). Currently, NASA's current weather forecast predicts a 90% chance of good weather for the launch. You can watch the launch live here on Space.com, courtesy of NASA T
  
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• Google kickstarts plan to boost internet speeds in Cuba

  22-03-2016 14:16 via cbc.ca
  
  President Barack Obama says Google's efforts in Cuba are part of a wider plan to improve access to the internet across the island.
  
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• Space Station Cargo Launch Tonight May Be Visible Along East Coast

  22-03-2016 13:59
  
  People in eastern North America have a chance to see a private cargo spacecraft launch toward the International Space Station tonight (March 22). Orbital ATK's robotic Cygnus spacecraft is scheduled to launch atop a United Launch Alliance Atlas V rocket from Cape Canaveral Air Force Station in Florida tonight at 11:05 p.m. EDT (0305 GMT on Wednesday, March 23). The launch will take Cygnus on a path nearly parallel to the U.S. East Coast, and the glow created by the Atlas V's engines should there
  
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• Minor Lunar Eclipse to Darken Part of Moon Wednesday: What to Expect

  22-03-2016 13:59
  
  Earth's shadow will darken part of the moon Wednesday morning (March 23) in a lunar eclipse that will be visible from much of the globe, including central and western North America. Wednesday's lunar eclipse is of the penumbral variety, and the effect will therefore be subtle and subdued compared to the jaw-dropping "blood moons" caused by total lunar eclipses. Earth's shadow is composed of two parts: the dark, inner umbra and a faint, outer portion called the penumbra.
  
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• Incoming Comet to Buzz Earth in Historic Close Flyby

  22-03-2016 13:54
  
  Comet 252P was discovered by MIT's Lincoln Near Earth Asteroid Research (LINEAR) survey in April 2000; the University of Hawaii's Pan-STARRS telescope found Comet P/2016 BA14 just two months ago, on Jan. 22, 2016.
  
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• Pharaoh Ramesses III Killed by Multiple Assailants, Radiologist Says

  22-03-2016 13:38
  
  The New Kingdom Pharaoh Ramesses III was assassinated by multiple assailants — and given postmortem cosmetic surgery to improve his mummy's appearance. Those are some of the new tidbits on ancient Egyptian royalty detailed in a new book by Egyptologist Zahi Hawass and Cairo University radiologist Sahar Saleem, "Scanning the Pharaohs: CT Imaging of the New Kingdom Royal Mummies" (American University in Cairo Press, 2016). Hawass and Saleem studied royal mummies from the 18th to 20th dynasti
  
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• 'Boaty McBoatface' Tops Poll to Name Polar Research Vessel

  22-03-2016 13:35
  
  "Name our ship!" This was the call from the Natural Environment Research Council (NERC) in an online poll soliciting names for a U.K. polar research vessel. The whimsical suggestion captured the public imagination and rocketed the humorous moniker into first place, trouncing even recommendations honoring beloved British icons like Sir Richard Attenborough and recently deceased musician David Bowie. The British Antarctic Survey (BAS) currently boasts two polar research vessels — a stately p
  
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• 'Boaty McBoatface' Controversy: How Ships Get Named

  22-03-2016 13:35
  "Name our ship!" This was the call from the Natural Environment Research Council (NERC) in an online poll soliciting names for a U.K. polar research vessel. And the Internet responded in the most predictable way possible: The people have spoken — and the name they want is "Boaty McBoatface."
  
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• Flint's Lead-Tainted Water May Not Cause Permanent Brain Damage

  22-03-2016 13:00 via rss.sciam.com
  
  The contamination of drinking water was a public health disaster, but children who were exposed can still be helped
  -- Read more on ScientificAmerican.com
  
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• Iraq seeks financial agreement with Kurds before pumping crude to Turkey

  22-03-2016 12:52
  Iraq will not resume pumping crude through a Kurdish pipeline to Turkey unless it reaches a financial agreement with the Kurdish regional government, the Iraqi oil minister said on Tuesday. Adel Abdul Mahdi confirmed on his Facebook page that the central Iraqi government had decided to stop pumping crude from fields under the management of its state-run company in northern Iraq through the pipeline.He said state-run North Oil Company previously fed 150,000 barrels a day into the pipeline that ca
  
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• DNA data storage could last thousands of years

  22-03-2016 12:43
  
  Researchers in Switzerland have developed a method for writing vast amounts of information in DNA and storing it inside a synthetic fossil, potentially for thousands of years.
  
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• Apparently many studies claiming that moderate alcohol consumption is healthy are 'biased'

  22-03-2016 10:51
  
  Sorry about that.
  
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• China says Philippine fishermen used fire bombs in South China Sea

  22-03-2016 10:13
  Philippine fishermen threw fire bombs at Chinese law enforcement vessels in the South China Sea, China's Foreign Ministry on Tuesday, after Philippine media said fishermen had been struck by bottles hurled from Chinese coast guard ships. China and the Philippines have long exchanged accusations about each other's behaviour in the disputed South China Sea. China claims most of the energy-rich waters through which about $5 trillion in ship-borne trade passes every year.
  
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• On World Water Day, here's a look at some of the places that don't have enough

  22-03-2016 10:00 via cbc.ca
  
  The UN estimates that some 650 million people, or one in 10 of the world's population, lack access to clean water, putting them at risk of infectious diseases and death. To mark World Water Day, held on March 22, here's a look at some of the places that don't have enough of the precious resource.
  
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• 7 places you won't believe scientists are looking for new antibiotics

  22-03-2016 07:31
  
  Leafants, marine sponges, soil and even men’s beards…
  
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• Why sexual harassment is worse than other types of abuse online

  22-03-2016 05:00
  
  (Ohio State University) While many women gamers can shrug off much of the name-calling and abuse they receive while playing online video games, sexual harassment sticks with them even when they're offline.
  
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