• Shaky on Payment? Here's a Primer

    Bonnie Kirschenbaum, MS, FASHP,FCSHP“Reimbursement Matters” is a tool for maintaining your health system’s fiscal health. Please email the author at [email protected] with suggestions on reimbursement issues that you would like to see covered.This column is an introduction (or refresher) for new graduates joining the workforce and coming face-to-face with the realities of how medications are paid for in outpatient environments such as infusion clinics or ambulatory s
  • A Synergy of CAR-T Hematotoxicity Scoring Tools

    Two scoring tools used to predict hematologic toxicity after chimeric antigen receptor T-cell (CAR-T) therapy demonstrated comparable overall accuracy in a single-center retrospective study, but a closer look at their performance revealed a meaningful difference that suggests each tool may be best suited to a different phase of patient care, according to study results (poster TR002).The study compared CAR-HEMATOTOX and KyoTox in 60 adults with B-cell lymphoma who received CD19-directed CAR-T the
  • Cefepime-Induced Neurotoxicity Can Occur Even With Guideline-Directed Dosing

    More than half of patients received potentially neurotoxic doses of cefepime, according to a new retrospective analysis. Even guideline-directed dosing resulted in excessive cefepime trough levels.“Ninety-six percent of these patients did achieve target attainment. This suggests a low risk of treatment failure,” said presenting author Jillian Lachapelle, PharmD, a PGY-2 critical care pharmacy resident at MaineHealth Maine Medical Center, in Portland. The concern is not cefepime's the
  • Short-Course Abx Therapy Appropriate For Hospital-Acquired Pneumonia in ICUs

    Short-course antibiotic therapy is just as effective as longer courses for preventing pneumonia recurrence in ICU patients, investigators at the University of Missouri Health Care, in Columbia, reported.Shorter courses are known to be effective at reducing recurrence after ventilator-associated pneumonia; for the study, researchers investigated whether shorter courses also have benefit for non-ventilated ICU patients with hospital-acquired pneumonia (HAP).“We met noninferiority for our sho
  • Advertisement

  • Better Follow-up Needed for Patients With Actinomyces Infections

    A University of Kentucky (UK) HealthCare study found that although some patients admitted for surgery received appropriate antibiotics during their stay for Actinomyces species infection, there was a steep dropoff in such prescribing at discharge, including delayed treatment starts.As a result, “there were some patients who had more than one readmission,” noted Ann Margaret Routon, PharmD, a PGY-2 critical care pharmacy resident who presented UK HealthCare's analysis.The study began
  • The Benefits of a Structured Pediatric HPN Discharge Model

    By Gina ShawFor children with intestinal failure, discharge on home parenteral nutrition (HPN) represents a high-risk transition. At the ASPEN 2026 Nutrition Science & Practice Conference, in Long Beach, California, clinicians from Boston Children's Hospital outlined a structured, multidisciplinary approach designed to reduce complications, prevent ambulatory central line–associated bloodstream infections (CLABSIs), and support families managing complex therapy at home.“Home pare
  • Malnutrition in Solid-Organ Transplant Calls for Timely PN Application

    By Susan KreimerMalnutrition is prevalent in patients undergoing solid-organ transplant and influences the initiation and selection of enteral (EN) and parenteral (PN) nutrition strategies, speakers said at the ASPEN 2026 Nutrition Science & Practice Conference, in Long Beach, California.The speakers emphasized the importance of interprofessional healthcare team collaboration to optimize nutrition support in patients receiving transplants.“Transplant patients are becoming increasingly
  • Clinical Characterization and Multimodal Management Of Pediatric Acute-Onset Neuropsychiatric Syndrome

    Amy E. Clarke, DNP, RN, IgCN®Chief Clinical OfficerImmunoglobulin National SocietyCalabasas, CaliforniaLuba Sobolevsky, PharmD, IgCP®President and CEOImmunoglobulin National SocietyCalabasas, CaliforniaPediatric acute-onset neuropsychiatric syndrome (PANS) is a constellation of psychiatric and neurologic symptoms characterized by abrupt, dramatic onset and functional disruption. Although the underlying pathophysiology remains incompletely defined, PANS is conceptualized as a postinfectio
  • Advertisement

  • Biosimilar Uptake Surges After Order Set Change at an Academic Center

    Switching the default product in electronic order sets from originator biologics to preferred formulary biosimilars dramatically increased biosimilar utilization for commonly prescribed oncology infusion agents, according to a presentation from researchers at the University of Arkansas for Medical Sciences (UAMS).Those results offer a model for health-system pharmacists seeking to accelerate biosimilar adoption without a major overhaul to clinical workflows, said presenting author Sidney Keisner
  • Gut Check: Gastric and Esophageal Cancer Treatment Evolves

    Oncology pharmacists managing patients with gastric and esophageal cancers now have a novel therapeutic agent to work with.Zolbetuximab (Vyloy, Astellas), the first-in-class CLDN18.2-targeting monoclonal antibody approved last year for first-line HER2-negative gastric and esophagogastric junction (EGJ) adenocarcinoma, can extend overall survival (OS) beyond the 18-month mark for eligible patients, explained Jeremy Pappacena, PharmD, BCOP, a clinical pharmacy specialist in medical oncology at All
  • Tackling Burnout in Pharmacy Technicians

    By Naveed Saleh, MD, MSRates of burnout among pharmacy technicians are concerningly high, and more than two-thirds of survey respondents reported that burnout has a significant impact on well-being at their institution, according to a study presented at the ASHP Midyear 2025 Clinical Meeting & Exhibition, in Las Vegas (poster 8-195). The authors also reported that lower grit and resilience among survey respondents corresponded with higher levels of emotional exhaustion and depersonalization.
  • Building a Sterile Compounding Program With a High Reliability Model

    By Gina ShawLauren Bristow, PharmDAs regulatory expectations increase and operational complexity grows, compounding teams are searching for frameworks that can help them deliver consistent safety in an inherently unstable environment.During a recent webinar on cleanroom collaboration, pharmacy leaders discussed how the principles of high reliability organizations (HROs) can offer one such framework.“What drew me to high reliability in healthcare is that its principles come from high-stakes

Follow @newsl_pharmacy on Twitter!