Medical news

• RFK Jr. Unveils Autism Patient Database Project

  07-05-2025 23:14 via medpagetoday.com
  (MedPage Today) -- The NIH and the Centers for Medicare & Medicaid Services (CMS) will build a data platform to conduct research across claims data, electronic health record (EHR) data, and consumer wearables, HHS announced Wednesday.
  The...
  
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• U.S. Signs New Health Deals With 9 African Countries That Mirror Trump's Priorities

  23-12-2025 22:50 via medpagetoday.com
  (MedPage Today) -- The U.S. government has signed health deals with at least nine African countries, part of its new approach to global health funding, with agreements that reflect the Trump administration's interests and priorities and are geared...
  
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• Overcoming CDK4/6 Inhibitor Resistance in HR-Positive/HER2-Negative Breast Cancer

  23-12-2025 21:32 via medpagetoday.com
  (MedPage Today) -- In the decade since palbociclib (Ibrance) received FDA approval, results from multiple clinical trials have provided a strong evidence base to make cyclin-dependent kinase (CDK)4/6 inhibitors, in combination with endocrine therapy...
  
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• Alzheimer's Paper Retracted; Lipoic Acid and MS; Botched Autism Drug Rollout

  23-12-2025 20:26 via medpagetoday.com
  (MedPage Today) -- Science Signaling retracted a 2017 paper that linked a specific amyloid form (amyloid-beta 56) to tau pathology after an investigation into allegations of data manipulation. Author Sylvain Lesné, PhD, who resigned from the...
  
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• Assessing Non-Glandular Manifestations of Sjogren's Disease

  23-12-2025 19:19 via medpagetoday.com
  (MedPage Today) -- Beyond sicca symptoms, Sjögren's disease can involve non-glandular manifestations such as dysautonomia and small fiber neuropathy that are often difficult to assess and manage. At this year's American College of Rheumatology...
  
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• Prediabetes Reversal Benefits; Many Seniors Quit GLP-1s in a Year; Testosterone Fads

  23-12-2025 19:07 via medpagetoday.com
  (MedPage Today) -- Achieving prediabetes remission was tied to a decades-long benefit--a reduction in risk of cardiovascular death or hospitalization for heart failure--in a post-hoc analysis of two landmark diabetes prevention trials...
  
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• The Midterms Are Coming. Vaccines May Play a Role.

  23-12-2025 18:58 via medpagetoday.com
  (MedPage Today) -- Restricting access to vaccines and discouraging the development of new vaccines are grave public policy and public health mistakes. This will eventually have a catastrophic impact on children's health, be a major hit to workplace...
  
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• Long-Term Tofersen Use May Slow ALS Progression, 3-Year Data Suggest

  23-12-2025 18:46 via medpagetoday.com
  (MedPage Today) -- Early initiation of tofersen (Qalsody) was associated with a numerically slower decline in people with SOD1 amyotrophic lateral sclerosis (ALS) compared with delayed treatment, according to data from the VALOR trial and its open...
  
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• 'Armored' CAR T Cells Show Early Promise in Relapsed B-Cell ALL

  23-12-2025 18:16 via medpagetoday.com
  (MedPage Today) -- At the recent American Society of Hematology annual meeting, phase I data highlighted a next-generation, CD19-targeted, interleukin-18-secreting "armored" CAR T-cell therapy that is designed to enhance persistence and antileukemic...
  
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• FDA Approves First Oral Medication for Iron Deficiency in Kids

  23-12-2025 18:02 via medpagetoday.com
  (MedPage Today) -- The FDA has expanded the indication of ferric maltol (Accrufer) capsules for the treatment of iron deficiency to include adolescents.
  The approval makes the drug the first prescription oral medicine for iron deficiency in pediatric...
  
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• Blood-Based Immune Markers May Predict Response to Preoperative Therapy in TNBC

  23-12-2025 17:27 via medpagetoday.com
  (MedPage Today) -- At the San Antonio Breast Cancer Symposium, investigators reported findings from a retrospective study exploring whether routine blood-based immune markers could help predict response to neoadjuvant chemoimmunotherapy in early...
  
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• Reassuring Findings for Use of Common Sleep Medications in Pregnancy

  23-12-2025 17:14 via medpagetoday.com
  (MedPage Today) -- Exposure to nonbenzodiazepine sedative hypnotics, known as Z-drugs, in the first trimester of pregnancy was not associated with an increased risk of congenital malformations, a population-based cohort study suggested.
  Among...
  
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• Medicaid Paid More Than $207 Million for Dead People. A New Law Could Help Fix That.

  23-12-2025 16:40 via medpagetoday.com
  (MedPage Today) -- Medicaid programs made more than $200 million in improper payments to healthcare providers between 2021 and 2022 for people who had already died, according to a new report from the independent watchdog for the Department of Health...
  
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• The Promise of Biomarkers to Direct Chronic Spontaneous Urticaria Therapy

  23-12-2025 15:30 via medpagetoday.com
  (MedPage Today) -- Pathophysiologic biomarkers for chronic spontaneous urticaria (CSU) are emerging, which can help better target therapies for the potentially debilitating condition.
  Heterogeneity in CSU--characterized by spontaneous occurrence...
  
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• FDA Approves Wegovy Weight-Loss Pill

  23-12-2025 15:25 via medpagetoday.com
  (MedPage Today) -- The FDA approved a pill version of the GLP-1 receptor agonist semaglutide (Wegovy), making it the first oral GLP-1 agent indicated for weight loss, Novo Nordisk announced on Monday.
  The once-daily 25 mg pill is approved to lower...
  
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• Can You Pass a Health Scam Quiz? Trial Death Reported; Views on MMR Vax Slide

  23-12-2025 15:10 via medpagetoday.com
  (MedPage Today) -- Note that some links may require registration or subscription.
  Amid a heightened volume of health scams, this quiz may help determine your risk of falling for one. (New York Times)
  Pfizer said a patient in a trial of its hemophilia...
  
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• FcRn Blockers Vie to Become First Approved Drug for Sjogren's Disease

  23-12-2025 14:49 via medpagetoday.com
  (MedPage Today) -- The first FDA-approved treatment option for Sjögren's disease might be on the horizon, as neonatal Fc receptor (FcRn) blockers show promise in early data.
  B-cell activation in Sjögren's disease results in immunoglobulin...
  
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• Here's Where Measles Case Counts Are Highest

  23-12-2025 14:30 via medpagetoday.com
  (MedPage Today) -- Map highlights total U.S. cases in 2025 and past-week increases
  
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• Once-Weekly Oral Combo for HIV Maintains High Rates of Virologic Suppression

  22-12-2025 23:42 via medpagetoday.com
  (MedPage Today) -- A once-weekly oral combination of islatravir plus lenacapavir (Sunlenca) for HIV maintained similarly high rates of virologic suppression compared with standard daily oral treatment in an open-label phase II trial.
  In 104 virologically...
  
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• I've Survived Two School Shootings. I Implore You to Speak Up.

  22-12-2025 23:12 via medpagetoday.com
  (MedPage Today) -- If you've read the news recently, chances are you have seen the headlines about the mass shooting at Brown University that killed two of my fellow Brown students and injured nine others. You might have also seen me on the news...
  
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• More Americans Experience Troublesome Healthcare Costs Than Previously Thought

  22-12-2025 23:03 via medpagetoday.com
  (MedPage Today) -- A greater share of Americans than previously suggested experience burdensome healthcare costs, according to results from a nationally representative cohort study.
  Among more than 12,600 survey participants, 6.5% said they experienced...
  
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• Air Pollution Linked to Depression

  22-12-2025 22:07 via medpagetoday.com
  (MedPage Today) -- Long-term exposure to pollution from fine particulate matter and its major components--soil dust, sulfate, and elemental carbon--correlated with a greater risk of depression among older adults, a U.S. study showed.
  In...
  
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• Nirsevimab Might Top Maternal Vax for Infants' RSV Protection

  22-12-2025 21:50 via medpagetoday.com
  (MedPage Today) -- Infants given the monoclonal antibody nirsevimab (Beyfortus) to provide passive immunity against respiratory syncytial virus (RSV) had a lower rate of related hospitalizations and severe outcomes than those whose mothers got...
  
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• Benzodiazepines Linked With Adverse Pregnancy Outcomes

  22-12-2025 21:25 via medpagetoday.com
  (MedPage Today) -- Use of benzodiazepines during pregnancy, particularly in the second trimester, was linked to some adverse pregnancy outcomes, a Taiwanese cohort study found.
  Among 454,477 pregnancies, benzodiazepine use was associated with...
  
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• FDA Opens Door to Quicker Approval of Osteoporosis Drugs

  22-12-2025 21:19 via medpagetoday.com
  (MedPage Today) -- The FDA gave the greenlight to use total hip bone mineral density (BMD) as a validated surrogate endpoint for clinical osteoporosis drug trials, the FDA announced on Friday.
  A BMD test measures calcium and other bone minerals...
  
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• CMS Funds 400 New Residency Slots

  22-12-2025 21:07 via medpagetoday.com
  (MedPage Today) -- The decision to fund 400 new medical residency positions at hospitals across the U.S. marks a meaningful--though limited--step toward addressing a looming physician shortage expected to worsen over the next decade, public...
  
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• Half of Transgender, Gender Diverse Youth Report Suicidal Thoughts

  22-12-2025 20:55 via medpagetoday.com
  (MedPage Today) -- Nearly one in two transgender and gender diverse (TGD) youth reported suicidal ideation or self-injury, and one in four attempted suicide, a global meta-analysis showed.
  In a study of 131,429 TGD individuals ages 25 and younger...
  
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• Twins Joined at the Heart: Single Embryo Transfer Results in Unusual Case

  22-12-2025 19:17 via medpagetoday.com
  (MedPage Today) -- When a woman in her mid-40s underwent a single, genetically normal embryo transfer, clinicians expected--and counseled for--a singleton pregnancy.
  What followed instead was one of the rarest outcomes in assisted reproduction...
  
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• Study: Keep Hydroxychloroquine Doses High in Lupus

  22-12-2025 19:13 via medpagetoday.com
  (MedPage Today) -- Hydroxychloroquine (HCQ) doses of at least 400 mg/day provided better symptom relief for Taiwanese people with systemic lupus erythematosus (SLE) compared with lower doses, with the added benefit of less risk for cardiovascular...
  
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• Adding Tucatinib in First-Line Maintenance Boosts PFS in HER2-Positive Breast Cancer

  22-12-2025 18:56 via medpagetoday.com
  (MedPage Today) -- At the San Antonio Breast Cancer Symposium, investigators presented results from HER2CLIMB-05, a registrational trial evaluating the addition of tucatinib (Tukysa) to trastuzumab (Herceptin) and pertuzumab (Perjeta) maintenance...
  
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